KEGG   Homo sapiens (human): 246778
Entry
246778            CDS       T01001                                 
Symbol
IL27, IL-27, IL-27A, IL27A, IL27p28, IL30, p28
Name
(RefSeq) interleukin 27
  KO
K22629  interleukin 27 subunit alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04659  Th17 cell differentiation
Network
nt06518  JAK-STAT signaling
  Element
N01556  IL6 family to Jak-STAT signaling pathway
N01559  Type II interferon to Jak-STAT signaling pathway
Drug target
Casdozokitug: D12784
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    246778 (IL27)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    246778 (IL27)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    246778 (IL27)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    246778 (IL27)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Interleukins
   246778 (IL27)
SSDB
Other DBs
NCBI-GeneID: 246778
NCBI-ProteinID: NP_663634
OMIM: 608273
HGNC: 19157
Ensembl: ENSG00000197272
UniProt: Q8NEV9
Structure
Position
16:complement(28499362..28506834)
AA seq 243 aa
MGQTAGDLGWRLSLLLLPLLLVQAGVWGFPRPPGRPQLSLQELRREFTVSLHLARKLLSE
VRGQAHRFAESHLPGVNLYLLPLGEQLPDVSLTFQAWRRLSDPERLCFISTTLQPFHALL
GGLGTQGRWTNMERMQLWAMRLDLRDLQRHLRFQVLAAGFNLPEEEEEEEEEEEEERKGL
LPGALGSALQGPAQVSWPQLLSTYRLLHSLELVLSRAVRELLLLSKAGHSVWPLGFPTLS
PQP
NT seq 732 nt   +upstreamnt  +downstreamnt
atgggccagacggcaggcgaccttggctggcggctcagcctgttgctgcttcccttgctc
ctggttcaagctggtgtctggggattcccaaggcccccagggaggccccagctgagcctg
caggagctgcggagggagttcacagtcagcctgcatctcgccaggaagctgctctccgag
gttcggggccaggcccaccgctttgcggaatctcacctgccaggagtgaacctgtacctc
ctgcccctgggagagcagctccctgatgtttccctgaccttccaggcctggcgccgcctc
tctgacccggagcgtctctgcttcatctccaccacgcttcagcccttccatgccctgctg
ggagggctggggacccagggccgctggaccaacatggagaggatgcagctgtgggccatg
aggctggacctccgcgatctgcagcggcacctccgcttccaggtgctggctgcaggattc
aacctcccggaggaggaggaggaggaagaggaggaggaggaggaggagaggaaggggctg
ctcccaggggcactgggcagcgccttacagggcccggcccaggtgtcctggccccagctc
ctctccacctaccgcctgctgcactccttggagctcgtcttatctcgggccgtgcgggag
ttgctgctgctgtccaaggctgggcactcagtctggcccttggggttcccaacattgagc
ccccagccctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
3D Structure (3)   
   PDB (3)   
All databases (33)   

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