KEGG   Homo sapiens (human): 253152
Entry
253152            CDS       T01001                                 
Symbol
EPHX4, ABHD7, EH4, EPHXRP
Name
(RefSeq) epoxide hydrolase 4
  KO
K22369  epoxide hydrolase 4 [EC:3.3.-.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05207  Chemical carcinogenesis - receptor activation
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06251  CYP-mediated ROS formation (cancer)
  Element
N01401  Benzo[a]pyrenre to CYP-mediated metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    253152 (EPHX4)
   05208 Chemical carcinogenesis - reactive oxygen species
    253152 (EPHX4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    253152 (EPHX4)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S33
   253152 (EPHX4)
SSDB
Motif
Pfam: Abhydrolase_1 Abhydrolase_6 Hydrolase_4 Ndr PGAP1
Other DBs
NCBI-GeneID: 253152
NCBI-ProteinID: NP_775838
OMIM: 617401
HGNC: 23758
Ensembl: ENSG00000172031
UniProt: Q8IUS5
Position
1:92029985..92063538
AA seq 362 aa
MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPP
ACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEY
RVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAI
CYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKH
LFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTL
LLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRK
KD
NT seq 1089 nt   +upstreamnt  +downstreamnt
atggcgaggctgcgggattgcctgccccgcctgatgctcacgctccggtccctgctcttc
tggtccctggtctactgctactgcgggctctgcgcctccatccacctgctcaaacttttg
tggagcctcggcaaggggccggcgcagaccttccggcggcccgcccgggagcaccctccc
gcgtgcctgagcgacccctccttgggcacccactgctacgtgcggatcaaggattcaggg
ttaagatttcactatgttgctgctggagaaagaggcaaaccacttatgctgctgcttcat
ggatttccagaattctggtattcttggcgttaccaactgagagaatttaaaagtgaatat
cgagttgtagcactggatttgagaggttatggagaaacagatgctcccattcatcgacag
aattataaattggattgtctaattacagatataaaggatattttagattctttagggtat
agcaaatgtgttcttattggccatgactgggggggcatgattgcttggctaattgccatc
tgttatcctgaaatggtgatgaagcttattgttattaacttccctcatccaaatgtattt
acagaatatattttacgacaccctgctcagctgttgaaatccagttattattacttcttc
caaataccatggttcccagaatttatgttctcaataaatgatttcaaggttttgaaacat
ctgtttaccagtcacagcactggcattggaagaaaaggatgccaattaacaacagaggat
cttgaagcttatatttatgtcttttctcagcctggagcattaagtggcccaattaaccat
taccgaaatatcttcagctgcctgcctctcaaacatcacatggtgaccactccaacacta
ctactgtggggagagaatgacgcattcatggaggttgagatggctgaagtcacaaagatt
tatgttaaaaactatttcaggctaactattttgtcagaagccagtcattggcttcagcaa
gaccaacctgacatagtgaacaaattgatatggacatttctaaaagaagaaacaagaaaa
aaagattga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (40)   

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