KEGG   Homo sapiens (human): 257202
Entry
257202            CDS       T01001                                 
Symbol
GPX6, GPX5p, GPXP3, GPx-6, GSHPx-6, dJ1186N24, dJ1186N24.1
Name
(RefSeq) glutathione peroxidase 6
  KO
K00432  glutathione peroxidase [EC:1.11.1.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00480  Glutathione metabolism
hsa01100  Metabolic pathways
hsa04918  Thyroid hormone synthesis
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06026  Glutathione biosynthesis
nt06525  Ferroptosis
  Element
N01589  Glutathione biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    257202 (GPX6)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    257202 (GPX6)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    257202 (GPX6)
   05016 Huntington disease
    257202 (GPX6)
   05022 Pathways of neurodegeneration - multiple diseases
    257202 (GPX6)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.9  glutathione peroxidase
     257202 (GPX6)
SSDB
Motif
Pfam: GSHPx
Other DBs
NCBI-GeneID: 257202
NCBI-ProteinID: NP_874360
OMIM: 607913
HGNC: 4558
Ensembl: ENSG00000198704
UniProt: P59796
Position
6:complement(28503296..28515793)
AA seq 221 aa
MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA
GKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK
YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR
WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH
NT seq 666 nt   +upstreamnt  +downstreamnt
atgttccagcagttccaggcctcctgtcttgtcctgtttttcctggttggctttgctcag
cagaccctaaagcctcaaaataggaaggtggattgcaacaaaggggtaacaggcaccatc
tatgagtatggagccctcaccctcaacggcgaggagtacatccaattcaagcagtttgca
ggcaagcacgtcctgtttgtcaatgtggccgcctattgaggcttggcagctcagtatcct
gaactgaatgcactacaggaggagctgaagaattttggtgtcattgtgttggcctttccc
tgcaaccagtttggaaaacaagaaccaggaacaaactcagaaatacttcttggtctcaag
tatgtgtgtccaggtagtggctttgtccccagtttccagctctttgagaaaggggatgtg
aatggagaaaaagaacagaaggtctttactttcctgaagaactcctgccctccgacctct
gatcttttgggctcatcaagccaactcttctgggagcccatgaaggtccatgatatccgc
tggaactttgagaaatttctggtggggcccgatggagtccctgtcatgcattggttccac
caggctccagtcagcacagtcaagtcagacatcctggagtacctaaagcagttcaatacc
cactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (1)   
   Pfam (1)   
All databases (40)   

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