KEGG   Homo sapiens (human): 257218
Entry
257218            CDS       T01001                                 
Symbol
SHPRH, RAD5, bA545I5.2
Name
(RefSeq) SNF2 histone linker PHD RING helicase
  KO
K15710  E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    257218 (SHPRH)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     257218 (SHPRH)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    257218 (SHPRH)
SSDB
Motif
Pfam: SNF2-rel_dom SHPRH_helical-1st SHPRH_helical-2nd Linker_histone Helicase_C zf-RING_UBOX PHD zf-C3HC4 zf-RING_2 zf-C3HC4_2 zf-C3HC4_3 zf-RING_5 TPR_12 TPR_10
Other DBs
NCBI-GeneID: 257218
NCBI-ProteinID: NP_001036148
OMIM: 608048
HGNC: 19336
Ensembl: ENSG00000146414
UniProt: Q149N8 B3KX98
Structure
Position
6:complement(145857838..145964358)
AA seq 1683 aa
MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
ELE
NT seq 5052 nt   +upstreamnt  +downstreamnt
atgagcagccgacggaaacgtgctcctccagtgagggtagatgaggaaaagaggcagcag
cttcattggaatatgcatgaggacagaaggaatgaacctatcatcataagtgatgatgac
gagcagccctgcccaggttcagatacctcttctgctcattatatcattctaagtgatagt
ctaaaggaagaagtggctcacagagataagaagaggtgttcaaaagtggtgagcttctca
aaaccaattgaaaaagaagagactgttggtattttttcccctttgtctgtaaagttaaat
attgtgatttctccctatcattttgataattcctggaaagcatttctaggagaattaact
cttcagcttcttcctgcacagagtttaattgaaaatttttccgaaaggagtattacattg
atgagttcagagtcaagcaatcagttcctgatttatgttcattcaaaaggtgaagatgta
gagaaacaaaaaaaagaaccgatgagtatttgtgacaagggtattctggtggagtcatcc
ttcagtggtgaaatgttagaagatttggggtggctacaaaagaagagaagaataaaactc
tatcagaaaccagaaggaaatcacattatcaaggttggaatttatcttttggaagctggc
ctagcaaaactagacttcttgagtgatgcaaattcaagaatgaaaaagttcaatcagctc
atgaagaaagtaatggaaaagttacacaattctattattccagatgtgttggaagaggat
gaagatgatccggagagtgagccagagggacaagacattgacgagctgtatcactttgtg
aaacaaacacatcagcaagaaacgcagtccatccaagtggatgtccagcatcctgcattg
atccctgtgttgagaccctaccaaagagaggctgtcaattggatgctacaacaagagtgt
ttcagaagcagtcctgctactgaaagtgccctgcacttcttatggcgagagattgttaca
tctgagggtctgaaactctactataatccatatacaggctgcatcattcgtgagtaccca
aattctgggccgcagttgcttggtggaattttagcagatgagatgggtcttggaaagaca
gtggaggttttggctctgattctgacacatactcgacaagatgtcaagcaagatgctctc
actcttcccgagggaaaagtggtgaattattttattccgtcacattattttggaggaaaa
ctgaaaaagacagaaatccagaatatcgaatttgaaccaaaagaaaaagttcaatgccct
cctacacgtgtgatgatactgacagctgtgaaagaaatgaatggaaaaaaaggagtgtcc
atcctttccatctataagtatgtcagttctatatatagatacgatgttcaacggaacagg
agtcttttgaaacggatgctgaaatgtttaatttttgaaggtctcgtgaaacagatcaaa
ggccatggtttttctgggacttttacattgggaaagaattacaaggaagaggatatatgt
gataaaacaaaaaagcaggcagtagggagtccaaggaaaattcagaaagaaactagaaaa
tcagggaacaaggacacagattctgaatacttgccatcagacacctctgatgatgatgat
gatccttactattattattataagtccaggagaaatcgcagtaaattgaggaaaaagctt
gttccatccacaaaaaaaggaaaaagtcaaccatttatcaatcccgattcacaaggtcac
tgtccagctactagcgactctggaataactgatgttgctatgtctaaaagtacatgtatc
tctgaattcaaccaagaacatgaaacagaggactgtgctgaatctctaaatcatgctgat
agtgatgtaccaccttctaataccatgagtccctttaacacctctgattaccgctttgag
tgtatatgtggtgaacttgatcagatagatcgtaagcctcgtgttcaatgcctgaagtgt
cacctgtggcaacatgcaaagtgtgtgaattatgatgagaaaaatctgaagatcaagcct
ttttactgcccccactgccttgttgcaatggaaccagtgtcaacaagagcaactctgatc
atctctccaagttccatctgtcaccagtgggtggatgagatcaacaggcatgtgaggtcg
tcatctcttcgagtcttggtatatcaaggagtgaagaaagatggctttttacaacctcat
tttttggcagaacaggatatagttatcattacctatgatgtactgcgttcagaattaaat
tatgtcgatatcccacatagcaatagtgaggatgggcgtcgcctacggaaccagaagcgc
tatatggctatcccgagccccctggtagctgtggagtggtggaggatctgccttgatgaa
gctcagatggttgagtgtcccacagtaaaagctgcagaaatggcccagcgtttgagtggg
attaatcgatggtgtatcagtggcactccagtacagagaggattagaggatctttttggg
ttagtggtctttcttggtattgaaccttactgtgtcaaacactggtgggttcgacttctc
tatcggccttactgcaagaagaatcctcagcatctctacagctttattgccaagatactg
tggaggtctgcaaagaaagatgtgattgaccaaatccaaataccaccacaaaccgaagaa
atacactggctccacttttctccagtggaaaggcatttctatcaccgtcagcatgaggtg
tgctgccaggatgtggtggtaaaactcaggaagatttctgactgggctctgaagctcagc
agcctagacagaaggactgtcacctctatcctgtatccattgctgaggctcagacaggcc
tgctgtcacccacaggctgttcgtggagagttcttgccactccaaaaaagcaccatgaca
atggaagagctgctgacatctttgcagaagaaatgtggaactgaatgtgaagaagcacat
cgacagctagtttgtgctctcaatggcttagcaggcattcatattattaaaggtgagtat
gccttggcagcagaattgtacagagaagtgttgcgctcctcggaggaacacaaaggaaaa
ctcaaaactgattcacttcaaagacttcatgctacccataacttgatggaattgttgata
gccaggcacccagggataccacctaccttgcgtgatggccgacttgaggaagaggccaaa
cagctgcgagagcactacatgagcaagtgtaatacagaagttgctgaagcccagcaagct
ttatatcctgtgcagcagaccatccatgagcttcaaagaaagattcattctaattctcct
tggtggctaaatgtgatccacagagcaatagaatttactattgatgaggagctagttcag
cgagtgcgaaatgaaataaccagcaactacaagcaacaaactggcaagctttctatgtca
gagaagttccgtgattgcagaggtcttcagttcttacttacaacacaaatggaagagcta
aataaatgccagaagctagtaagagaggctgtaaaaaacctggagggacctccatctcgt
aatgttattgagtctgcaacagtctgtcacctccgaccagccagacttcctctcaactgc
tgtgtcttttgtaaagctgatgaattgttcacagagtatgaatcaaagctattttccaac
acagtcaaaggccagactgcaatatttgaggagatgatagaagatgaagaaggactggtg
gatgatcgagcacctaccaccacccggggtctctgggcaataagtgagacagagcgatct
atgaaagcaatactatcatttgcaaaatcacataggtttgatgttgaatttgttgatgaa
ggaagcacttcaatggatctctttgaagcatggaagaaggaatataagttgcttcatgaa
tattggatggctctgaggaatcgtgtgtctgctgttgatgaacttgcaatggctacagaa
cgactaagagtgcgtgatcctagggagccaaagcctaatccgcctgttcttcatatcatt
gaaccacatgaggtagaacaaaaccgaataaaactactaaatgataaagctgttgctaca
tcacagcttcagaaaaaacttgggcagcttctttacctaactaatttggagaagtctcaa
gataaaacatcgggaggtgttaatccagaaccttgcccaatctgtgctcgacagctagga
aaacagtgggcggtactgacctgtggtcactgtttctgtaatgaatgcatttctataatt
attgaacaatacagcgtgggatctcacagaagctccattaagtgtgcaatctgccgccag
accacatctcacaaagaaatctcgtatgtctttacctcagagaaagcaaaccaggaggag
gacatccctgtgaagggcagccattctacaaaagtggaagctgtggtcagaactctgatg
aaaatacagcttagagatccaggggccaaagcactcgttttctcaacgtggcaagatgta
ttagatattatttcaaaagctcttactgacaacaacatggaatttgcacaaatcagtcgt
gttaagacatttcaggagaacctttcagcatttaaacgtgatccccaaatcaatattttg
ctgctgcccctgcacacaggttctaatggattaactatcattgaagcaactcatgttctc
ttggtggagcccatattgaaccctgcccatgagcttcaggccatagggagggtgcaccga
attggacagacaaaacctactattgtacacagattcttaattaaagcaacaatagaagaa
agaatgcaggcaatgctgaaaactgctgagagaagtcacacgaactcatcagcaaagcat
tcagaggcctctgtcttgactgtggctgacctggcagacctatttaccaaagaaactgaa
gagcttgaatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (31)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (28)   
DNA sequence (60)   
   RefSeq(nuc) (32)   
   GenBank (14)   
   EMBL (14)   
3D Structure (2)   
   PDB (2)   
Protein domain (14)   
   Pfam (14)   
All databases (145)   

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