KEGG   Homo sapiens (human): 25778
Entry
25778             CDS       T01001                                 
Symbol
DSTYK, CAKUT1, DustyPK, HDCMD38P, RHDNS1, RIP5, RIPK5, SPG23
Name
(RefSeq) dual serine/threonine and tyrosine protein kinase
  KO
K16288  dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
Organism
hsa  Homo sapiens (human)
Disease
H00266  Hereditary spastic paraplegia
H01867  Congenital anomalies of kidney and urinary tract
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    25778 (DSTYK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.1  dual-specificity kinase
     25778 (DSTYK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  Other
   25778 (DSTYK)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Haspin_kinase Kdo Kinase-like
Other DBs
NCBI-GeneID: 25778
NCBI-ProteinID: NP_056190
OMIM: 612666
HGNC: 29043
Ensembl: ENSG00000133059
UniProt: Q6XUX3
Position
1:complement(205142505..205211702)
AA seq 929 aa
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN
HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD
CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH
QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL
VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER
SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK
ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI
VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL
ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM
LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF
AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR
GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY
NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL
KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWY
ICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLG
IVQPMLQGIMNRLCKSNSEQPNRGLDDST
NT seq 2790 nt   +upstreamnt  +downstreamnt
atggagggcgacggggtgccatggggcagcgagcccgtctcgggtcccggccccggcggc
ggcggaatgatccgcgagctgtgccggggcttcggccgctaccgccgctacctgggacgg
ctgcgacagaacctgcgcgagacccagaagttcttccgcgacatcaagtgctcccacaac
cacacttgtctctcctccctcacgggcggcggcggggccgagcgcggccctgcaggcgat
gtcgccgaaaccgggctgcaggcgggccaactgagctgcatttccttcccacctaaggaa
gagaagtacctccagcagattgtggactgcctcccttgcatactgatcctcggccaggat
tgtaacgtcaagtgccagctgttgaatctgctgttgggggtgcaggtgcttcccaccacc
aagctgggcagtgaggagagctgtaagcttcggcgcctccgcttcacctatgggactcag
actcgggtcagcctggcgctccctggacagtatgaactagtgcacacgctggttgctcat
cagggcaactgggagaccatccctgaggaggatctggaggtccaagagaacaatgaggat
gctgctcatgttttagcggaactggaggtaacgatgcaccatgctctcttacaggaagtg
gacgttgtggtagcaccatgccaaggcctccggcccacagtggatgttctgggtgacttg
gtgaatgatttcttgcctgtgataacctatgcactccacaaagatgaactctctgagagg
gatgagcaagagcttcaggaaatccgaaagtatttctcctttcctgtattctttttcaaa
gtgccgaaactgggctcggagataatagactcctcaaccaggagaatggagagcgaaaga
tcaccgctttatcgccagctaattgacctgggctatctgagcagcagtcactggaactgt
ggggctcctggccaggatactaaagctcagagcatgttggtggaacagagtgaaaagctg
agacacttgagcacattttctcaccaggtgttacagactcgcctggtggatgcagccaag
gccctgaacctggtgcactgccactgccttgacatctttattaaccaggcatttgacatg
cagcgggacctgcagatcactcccaaacgtctggaatatactcgaaaaaaggagaatgag
ttgtatgaatcattgatgaatattgccaaccgaaagcaggaggaaatgaaggatatgatt
gttgagacacttaataccatgaaggaggaacttctggatgatgctactaacatggagttt
aaagacgtcattgtccctgagaatggagaaccagtaggcaccagagagatcaaatgctgc
atccgacagatccaggaactcatcatctcccgacttaatcaggcagtggctaataagctg
atcagctcagtggattacctgagggaaagcttcgtcggaaccctggaacgatgtctgcag
agcctggagaagtctcaggatgtctcagttcacatcaccagtaattatctcaaacagatc
ttaaatgctgcctatcatgttgaagtcacgtttcactcagggtcgtcagttacaaggatg
ctatgggagcaaatcaaacagatcatccagcgcatcacatgggtgagcccacctgccatc
actctggaatggaagaggaaggtggcccaggaagccattgagagcctcagcgcctccaaa
ttggctaagagcatttgcagccaattccggactcggctcaatagttcccacgaggctttt
gcagcctccttgcggcagctggaagctggccactcaggccggttagagaaaacggaagat
ctatggctgagggttcggaaagatcatgctccccgcctggcccgcctttctctggaaagc
tgttctttacaggatgtcttgcttcatcgtaaacctaaactgggacaggaactgggccgg
ggccagtatggtgtggtatacctgtgtgacaactggggaggacacttcccttgtgccctc
aaatcagttgtccctccagatgagaagcactggaatgatctggctttggaatttcactat
atgaggtctctgccgaagcatgagcgattggtggatctccatggttcagtcattgactac
aactatggtggtggctccagcattgctgtgctcctcattatggagcggctacaccgggat
ctctacacagggctgaaggctgggctgaccctggagacacgtttgcagatagcactagat
gtggtggagggaatccgcttcctgcacagccagggacttgtccatcgtgatatcaaactg
aaaaatgtgctgctggataagcagaaccgtgccaagatcactgacttaggattctgcaag
ccagaggccatgatgtcaggcagcattgtggggacaccaatccatatggcccctgaactt
ttcacagggaagtacgataattccgtggatgtctacgcttttggaattcttttctggtat
atctgctcaggctctgtcaagctccctgaggcatttgagaggtgtgctagcaaagaccat
ctctggaacaatgtgcggaggggggctcgcccagaacgtcttcctgtgtttgatgaggag
tgctggcagttgatggaagcctgttgggatggcgaccccttgaagaggcctctcttgggc
attgtccagcccatgctccagggcatcatgaatcggctctgcaagtccaattctgagcag
ccaaacagaggactagatgattctacttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (16)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (64)   
   RefSeq(nuc) (14)   
   GenBank (25)   
   EMBL (25)   
Protein domain (6)   
   Pfam (6)   
All databases (126)   

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