KEGG   Homo sapiens (human): 2584
Entry
2584              CDS       T01001                                 
Symbol
GALK1, GALK, GK1, HEL-S-19
Name
(RefSeq) galactokinase 1
  KO
K00849  galactokinase [EC:2.7.1.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00052  Galactose metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
hsa01100  Metabolic pathways
hsa01250  Biosynthesis of nucleotide sugars
Module
hsa_M00554  Nucleotide sugar biosynthesis, galactose => UDP-galactose
hsa_M00632  Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
Network
nt06023  Galactose degradation
  Element
N00847  Galactose degradation
Disease
H00070  Galactosemia
H02009  Galactokinase deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    2584 (GALK1)
   00520 Amino sugar and nucleotide sugar metabolism
    2584 (GALK1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2584 (GALK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.6  galactokinase
     2584 (GALK1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2584 (GALK1)
SSDB
Motif
Pfam: GalKase_gal_bdg GHMP_kinases_C GHMP_kinases_N
Other DBs
NCBI-GeneID: 2584
NCBI-ProteinID: NP_000145
OMIM: 604313
HGNC: 4118
Ensembl: ENSG00000108479
UniProt: P51570 V9HWE7
Structure
Position
17:complement(75751469..75765192)
AA seq 392 aa
MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM
TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAA
PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGM
PCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRR
RQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDY
RAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA
APHAMRHIQEHYGGTATFYLSQAADGAKVLCL
NT seq 1179 nt   +upstreamnt  +downstreamnt
atggctgctttgagacagccccaggtcgcggagctgctggccgaggcccggcgagccttc
cgggaggagttcggggccgagcccgagctggccgtgtcagcgccgggccgcgtcaacctc
atcggggaacacacggactacaaccagggcctggtgctgcctatggctctggagctcatg
acggtgctggtgggcagcccccgcaaggatgggctggtgtctctcctcaccacctctgag
ggtgccgatgagccccagcggctgcagtttccactgcccacagcccagcgctcgctggag
cctgggactcctcggtgggccaactatgtcaagggagtgattcagtactacccagctgcc
cccctccctggcttcagtgcagtggtggtcagctcagtgcccctggggggtggcctgtcc
agctcagcatccttggaagtggccacgtacaccttcctccagcagctctgtccagactcg
ggcacaatagctgcccgcgcccaggtgtgtcagcaggccgagcacagcttcgcagggatg
ccctgtggcatcatggaccagttcatctcacttatgggacagaaaggccacgcgctgctc
attgactgcaggtccttggagaccagcctggtgccactctcggaccccaagctggccgtg
ctcatcaccaactctaatgtccgccactccctggcctccagcgagtaccctgtgcggcgg
cgccaatgtgaagaagtggcccgggcgctgggcaaggaaagcctccgggaggtacaactg
gaagagctagaggctgccagggacctggtgagcaaagagggcttccggcgggcccggcac
gtggtgggggagattcggcgcacggcccaggcagcggccgccctgagacgtggcgactac
agagcctttggccgcctcatggtggagagccaccgctcactcagagacgactatgaggtg
agctgcccagagctggaccagctggtggaggctgcgcttgctgtgcctggggtttatggc
agccgcatgacgggcggtggcttcggtggctgcacggtgacactgctggaggcctccgct
gctccccacgccatgcggcacatccaggagcactacggcgggactgccaccttctacctc
tctcaagcagccgatggagccaaggtgctgtgcttgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
3D Structure (20)   
   PDB (20)   
Protein domain (3)   
   Pfam (3)   
All databases (85)   

Download RDF
DBGET integrated database retrieval system