KEGG   Homo sapiens (human): 26
Entry
26                CDS       T01001                                 
Symbol
AOC1, ABP, ABP1, DAO, DAO1, KAO
Name
(RefSeq) amine oxidase copper containing 1
  KO
K11182  diamine oxidase [EC:1.4.3.22]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
Drug target
Pimagedine hydrochloride: D05479
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    26 (AOC1)
   00340 Histidine metabolism
    26 (AOC1)
   00380 Tryptophan metabolism
    26 (AOC1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.4  Acting on the CH-NH2 group of donors
   1.4.3  With oxygen as acceptor
    1.4.3.22  diamine oxidase
     26 (AOC1)
SSDB
Motif
Pfam: Cu_amine_oxid Cu_amine_oxidN2 Cu_amine_oxidN3 DUF1965
Other DBs
NCBI-GeneID: 26
NCBI-ProteinID: NP_001082
OMIM: 104610
HGNC: 80
Ensembl: ENSG00000002726
UniProt: P19801
Structure
Position
7:150852120..150861504
AA seq 751 aa
MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS
TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP
GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR
CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG
KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP
RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG
GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE
MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH
ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT
NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM
ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI
ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD
NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
NT seq 2256 nt   +upstreamnt  +downstreamnt
atgccggccctgggctgggccgtggctgccatcctgatgctgcagacggccatggcggag
ccctccccggggactctgcccaggaaggcaggggtgttttcagacctaagcaaccaagag
ctgaaggcagtgcacagcttcctctggtccaagaaggagctgaggctgcagccctccagt
accaccaccatggccaagaacaccgtgtttctcatcgagatgctgctgcccaagaagtac
catgtgctgaggtttctggataaaggtgaaaggcatcctgtgcgggaagcccgtgccgtc
atcttctttggtgaccaggagcatcccaatgtcaccgagtttgctgtggggcccctgcca
gggccctgctacatgcgagcactgtcccccaggcctgggtaccagtcctcctgggcatcg
aggcccatctccacagcagagtatgccctcctctaccacaccctgcaggaagccaccaag
cccctgcatcagttcttcctcaataccacaggcttctcattccaagactgccatgacaga
tgcctggccttcaccgatgtggccccccggggtgtggcttctggccagcgccgcagttgg
cttatcatacagcgctatgtagaaggctactttctgcaccccactgggctggagctcctc
gtggatcatgggagcacagatgctgggcactgggccgtggagcaggtgtggtacaacggg
aagttctatgggagcccagaggaactggctcggaagtatgcagatggagaggtggacgtg
gtggtcctggaggacccgctgcctgggggcaaggggcatgacagcacagaggagccgccc
ctcttctcctcccacaagccccgcggggacttccccagccccatccatgtgagcggcccc
cgcttggtccagccccacggccctcgcttcaggctggagggcaacgctgtgctctacggc
ggctggagctttgccttccggctgcgctcctcctccgggctgcaggtcctgaacgtgcac
ttcggcggagagcgcattgcctatgaggtcagcgtgcaagaggcagtggcgctgtatgga
ggacacacacctgcaggcatgcagaccaagtacctcgatgtcggctggggcctgggcagc
gtcactcatgagttagcccccggcatcgactgcccggagaccgccaccttcctggacact
ttccactactatgatgccgatgacccggtccattatccccgagccctctgcctctttgaa
atgcccacaggggtgccccttcggcggcactttaattccaactttaaaggtggcttcaac
ttctatgcggggctgaagggccaggtgctggtgctgcggacaacttcaactgtctacaat
tatgattacatttgggactttatcttctaccccaacggggtgatggaggccaagatgcat
gccactggctacgtccacgccaccttctacacccccgaggggctgcgccacggcactcgc
ctgcacacccacctgattggcaacatacacactcacttggtgcactaccgcgtagacctg
gatgtggcaggcaccaagaacagcttccagacactgcagatgaagctagaaaacatcacc
aacccctggagcccaagacaccgcgtggtccagccaactctggagcagacgcagtactcc
tgggagcgccaggcggccttccgcttcaaaaggaagctgcctaagtacctgctctttacc
agcccccaggagaacccctggggccacaagcgcacgtaccgcctgcagatccactccatg
gccgaccaggtgctgcccccaggctggcaggaggagcaggccatcacctgggcaaggtac
cccctggcagtgaccaagtaccgggagtcggagctgtgcagcagcagcatctaccaccag
aacgacccctggcacccgcccgtggtctttgagcagtttcttcacaacaacgagaacatt
gaaaatgaggacctggtggcctgggtgacggtgggcttcctgcacatcccccactcagag
gacattcccaacacagccacacctgggaactccgtgggcttcctgctccggccattcaac
ttcttcccagaggacccctccctggcatccagagacactgtgatcgtgtggcctcgggac
aacggccccaactacgtccagcgctggatccctgaggacagggactgctcgatgcctccc
ccttttagctacaatgggacctatagacctgtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (27)   
   RefSeq(nuc) (9)   
   GenBank (9)   
   EMBL (9)   
3D Structure (5)   
   PDB (5)   
Protein domain (4)   
   Pfam (4)   
All databases (87)   

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