KEGG   Homo sapiens (human): 26019
Entry
26019             CDS       T01001                                 
Symbol
UPF2, HUPF2, RENT2, smg-3
Name
(RefSeq) UPF2 regulator of nonsense mediated mRNA decay
  KO
K14327  regulator of nonsense transcripts 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    26019 (UPF2)
   03015 mRNA surveillance pathway
    26019 (UPF2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    26019 (UPF2)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Surveillance complex
     26019 (UPF2)
   mRNA cycle factors
    P-body specific factors
     26019 (UPF2)
SSDB
Motif
Pfam: MIF4G Upf2
Other DBs
NCBI-GeneID: 26019
NCBI-ProteinID: NP_056357
OMIM: 605529
HGNC: 17854
Ensembl: ENSG00000151461
UniProt: Q9HAU5
Structure
Position
10:complement(11920022..12043170)
AA seq 1272 aa
MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL
EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ
MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT
ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL
LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE
SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF
TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL
DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA
ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA
EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN
RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI
ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES
HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY
KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED
VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG
VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE
VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK
DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT
DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV
AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN
QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN
ADLIFKTGGRRR
NT seq 3819 nt   +upstreamnt  +downstreamnt
atgccagctgagcgtaaaaagccagcaagtatggaagaaaaagactctttaccaaacaac
aaggaaaaagactgcagtgaaaggcggacagtgagcagcaaggagaggccaaaagacgat
atcaagctcactgccaagaaggaggtcagcaaggcccctgaagacaagaagaagagactg
gaagatgataagagaaaaaaggaagacaaggaacgcaagaaaaaagacgaagaaaaggtg
aaggcagaggaagaatcaaagaaaaaagaagaggaagaaaaaaagaaacatcaagaggaa
gagagaaagaagcaagaagagcaggccaaacgtcagcaagaagaagaagcagctgctcag
atgaaagaaaaagaagaatccattcagcttcatcaggaagcttgggaacgacatcattta
agaaaggaacttcgtagcaaaaaccaaaatgctccggacagccgaccagaggaaaacttc
ttcagccgcctcgactcaagtttgaagaaaaatactgcttttgtcaagaaactaaaaact
attacagaacaacagagagactccttgtcccatgattttaatggcctaaatttaagcaaa
tacattgcagaagctgtagcttccatcgtggaagcaaaactaaaaatctctgatgtgaac
tgtgctgtgcacctctgctctctctttcaccagcgttatgctgactttgccccatcactt
cttcaggtctggaaaaaacattttgaagcaaggaaagaggagaaaacacctaacatcacc
aagttaagaactgatttgcgttttattgcagaattgacaatagttgggattttcactgac
aaggaaggtctttccttaatctatgaacagctaaaaaatattattaatgctgatcgggag
tcccacactcatgtctctgtagtgattagtttctgtcgacattgtggagatgatattgct
ggacttgtaccaaggaaagtaaagagtgctgcagagaagtttaatttgagttttcctcct
agtgagataattagtccagagaaacaacagcccttccagaatcttttaaaagagtacttt
acgtctttgaccaaacacctgaaaagggaccacagggagctccagaatactgagagacaa
aacaggcgcattctacattctaaaggggagctcagtgaagatagacataaacagtatgag
gaatttgctatgtcttaccagaagctgctggcaaattctcaatccttagcagaccttttg
gatgaaaatatgccagatcttcctcaagacaaaccaacaccagaagaacatgggcctgga
attgatatattcacacctggtaaacctggagaatatgacttggaaggtggtatatgggaa
gatgaagatgctcggaatttttatgagaacctcattgatttgaaggcttttgtcccagcc
atcttgtttaaagacaatgaaaaaagttgtcagaataaagagtccaacaaagatgatacc
aaagaggcaaaagaatctaaggagaataaggaggtatcaagtcccgatgatttggaactt
gagttggagaatctagaaattaatgatgacaccttagaattagagggtggagatgaagct
gaagatcttacaaagaaacttcttgatgaacaagaacaagaagatgaggaagccagcact
ggatctcatctcaagctcatagtagatgctttcctacagcagttacccaactgtgtcaac
cgagatctgatagacaaggcagcaatggatttttgcatgaacatgaacacaaaagcaaac
aggaagaagttggtacgggcactcttcatagttcctagacaaaggttggatttgctacca
ttttatgcaagattggttgctacattgcatccctgcatgtctgatgtagcagaggatctt
tgttccatgctgaggggggatttcagatttcatgtacggaaaaaggaccagatcaatatt
gaaacaaagaataaaactgttcgttttataggagaactaactaagtttaagatgttcacc
aaaaatgacacactgcattgtttaaagatgcttctgtcagacttctctcatcaccatatt
gaaatggcatgcaccctgctggagacatgtggacggtttcttttcagatctccagaatct
cacctgaggaccagtgtacttttggagcaaatgatgagaaagaagcaagcaatgcatctt
gatgcgagatacgtcacaatggtagagaatgcatattactactgcaacccacctccagct
gaaaaaaccgtgaaaaagaaacgtcctcctctccaggaatatgtccggaaacttttgtac
aaggatctctctaaggttaccaccgagaaggttttgagacagatgcgaaagctgccctgg
caggaccaagaagtgaaagactatgttatttgttgtatgataaacatctggaatgtgaaa
tataatagtattcattgtgtagccaacctcttagcaggactagtgctctaccaagaggat
gttgggatccacgttgtggatggagtgttagaagatattcgattaggaatggaggttaat
caacctaaatttaatcagaggcgcatcagcagtgccaagttcttaggagaactttacaat
taccgaatggtggaatcagctgttattttcagaactctgtattcttttacctcatttggt
gttaatcctgatggctctccaagttccctggacccacctgagcatcttttcagaattaga
ctcgtatgcactattctggacacatgtggccagtactttgacagaggttccagtaaacga
aaacttgattgtttccttgtatattttcagcgttatgtttggtggaagaaaagtttggag
gtttggacaaaagaccatccatttcctattgatatagattacatgatcagtgatacacta
gaactgctaagaccaaagatcaaactctgtaattctctggaagaatccatcaggcaggta
caagacttggaacgagaattcttaataaaactaggcctagtaaatgacaaagactcaaaa
gattctatgacagaaggagaaaatcttgaagaggatgaagaagaagaagaaggtggggct
gaaacagaagaacaatctggaaatgaaagtgaagtaaatgagccagaagaagaggagggt
tctgataatgatgatgatgagggagaagaagaggaggaagagaatacagattaccttaca
gattccaataaggaaaatgaaaccgatgaagagaatactgaggtaatgattaaaggcggt
ggacttaagcatgtaccttgtgtagaagatgaggacttcattcaagctctggataaaatg
atgctagaaaatctacagcaacgaagtggtgaatctgttaaagtgcaccaactagatgtt
gccattcctttgcatctcaaaagccagctgaggaaagggcccccactgggaggtggggaa
ggagaggctgagtctgcagacacaatgccgtttgtcatgttaacaagaaaaggcaataaa
cagcagtttaagatccttaatgtacccatgtcctctcaacttgctgcaaatcactggaac
cagcaacaggcagaacaagaagagaggatgagaatgaaaaagctcacactagatatcaat
gaacggcaagaacaagaagattatcaagaaatgttgcagtctcttgcacagcgcccagct
ccagcaaacaccaatcgtgagaggcggcctcgctaccaacatccgaagggagcacctaat
gcagatctaatctttaagactggtgggaggagacgttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (49)   
   RefSeq(nuc) (7)   
   GenBank (21)   
   EMBL (21)   
3D Structure (6)   
   PDB (6)   
Protein domain (2)   
   Pfam (2)   
All databases (97)   

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