KEGG   Homo sapiens (human): 26061
Entry
26061             CDS       T01001                                 
Symbol
HACL1, 2-HPCL, HPCL, HPCL2, PHYH2
Name
(RefSeq) 2-hydroxyacyl-CoA lyase 1
  KO
K12261  2-hydroxyacyl-CoA lyase [EC:4.1.2.63]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04146  Peroxisome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    26061 (HACL1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.63  2-hydroxyacyl-CoA lyase
     26061 (HACL1)
SSDB
Motif
Pfam: TPP_enzyme_M TPP_enzyme_N TPP_enzyme_C CO_dh PcrB
Other DBs
NCBI-GeneID: 26061
NCBI-ProteinID: NP_036392
OMIM: 604300
HGNC: 17856
Ensembl: ENSG00000131373
UniProt: Q9UJ83
Position
3:complement(15560699..15601569)
AA seq 578 aa
MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNE
QAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMG
AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVN
VNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY
KLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVK
FIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSN
EAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDA
GTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVV
NNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQK
SLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNM
NT seq 1737 nt   +upstreamnt  +downstreamnt
atgccggacagtaacttcgcagagcgcagcgaggagcaggtgtctggtgctaaagtcatc
gctcaggccctgaaaacgcaagatgtggagtacatatttggcatcgtaggcatcccagtg
accgaaatcgccattgctgcccagcagctaggcatcaagtacatcgggatgaggaatgag
caagcggcttgttatgctgcctccgcgattggatatctgacaagcaggccaggagtctgc
cttgttgtttctggcccaggtctcatccatgccttgggcggtatggcaaatgcaaacatg
aactgctggcccttgcttgtgattggtggttcctctgaaagaaaccaagaaacaatggga
gctttccaggagtttcctcaggttgaagcttgtagattatataccaagttctctgcccgc
ccaagcagcatagaagctattccttttgttattgaaaaggcagtgagaagcagtatctat
ggtcgtccaggtgcttgctatgttgacataccagcagattttgtgaaccttcaggtgaat
gtgaattctataaagtacatggaacgctgcatgtcacctcctattagcatggcagaaacc
tctgctgtgtgcacggcggcttctgttattaggaatgccaaacaaccccttcttatcatc
gggaaaggtgctgcttacgctcatgcagaagagagtatcaagaaattggtggagcaatat
aaactgccatttttgcccacccctatggggaagggtgttgtccctgacaaccatccatac
tgtgtaggtgcagccagatccagggctttgcaatttgctgatgtaattgtgttatttggt
gccagactaaattggattttacattttggactgcctccaagatatcagccagatgtgaag
tttatccaggttgatatctgtgcagaagaattggggaataatgtaaagcccgctgttact
ttgctaggaaacatacatgctgtcactaagcagcttttagaggaacttgataaaacacca
tggcagtatcctccagagagcaagtggtggaaaactctgagagaaaaaatgaagagcaat
gaagctgcatccaaggaactagcttctaaaaaatccctgcctatgaattattacacagta
ttctaccatgttcaagaacaactacctagagactgtttcgtggtaagtgaaggagcaaat
actatggacattggacggactgtgcttcagaactaccttcctcgtcacaggcttgatgct
ggtactttcggaacaatgggagttggtttgggatttgctattgcagctgccgtggtggct
aaagatagaagccctgggcaatggatcatctgtgtggaaggagacagtgcatttgggttt
tctggcatggaggtagaaaccatctgcaggtacaacttgccaatcatactgttggtagtg
aataacaatggaatttaccaaggttttgatacagatacttggaaagaaatgttaaaattt
caagatgctactgcagtggtccctccaatgtgtttgctgccaaattcacattatgagcaa
gtcatgactgcatttggaggcaaagggtattttgtacaaacaccagaagaactccaaaaa
tccctgaggcagagcctagcagacacaactaaaccttctcttatcaacatcatgattgag
ccacaagccacacggaaggcccaggattttcattggctgacccgctctaatatgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
Protein domain (5)   
   Pfam (5)   
All databases (62)   

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