KEGG   Homo sapiens (human): 262
Entry
262               CDS       T01001                                 
Symbol
AMD1, ADOMETDC, AMD, SAMDC
Name
(RefSeq) adenosylmethionine decarboxylase 1
  KO
K01611  S-adenosylmethionine decarboxylase [EC:4.1.1.50]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00270  Cysteine and methionine metabolism
hsa00330  Arginine and proline metabolism
hsa01100  Metabolic pathways
Module
hsa_M00034  Methionine salvage pathway
Drug target
Mitoguazone: D07258
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    262 (AMD1)
   00330 Arginine and proline metabolism
    262 (AMD1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.50  adenosylmethionine decarboxylase
     262 (AMD1)
SSDB
Motif
Pfam: SAM_decarbox
Other DBs
NCBI-GeneID: 262
NCBI-ProteinID: NP_001625
OMIM: 180980
HGNC: 457
Ensembl: ENSG00000123505
UniProt: P17707 B4DZ60 A0A088AWN0 Q6N0B2
Structure
Position
6:110814617..110895713
AA seq 334 aa
MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQ
EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP
SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEIL
MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYW
TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQ
KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
NT seq 1005 nt   +upstreamnt  +downstreamnt
atggaagctgcacattttttcgaagggaccgagaagctgctggaggtttggttctcccgg
cagcagcccgacgcaaaccaaggatctggggatcttcgcactatcccaagatctgagtgg
gacatacttttgaaggatgtgcaatgttcaatcataagtgtgacaaaaactgacaagcag
gaagcttatgtactcagtgagagtagcatgtttgtctccaagagacgtttcattttgaag
acatgtggtaccaccctcttgctgaaagcactggttcccctgttgaagcttgctagggat
tacagtgggtttgactcaattcaaagcttcttttattctcgtaagaatttcatgaagcct
tctcaccaagggtacccacaccggaatttccaggaagaaatagagtttcttaatgcaatt
ttcccaaatggagcagcatattgtatgggacgtatgaattctgactgttggtacttatat
actctggatttcccagagagtcgggtaatcagtcagccagatcaaaccttggaaattctg
atgagtgagcttgacccagcagttatggaccagttctacatgaaagatggtgttactgca
aaggatgtcactcgtgagagtggaattcgtgacctgataccaggttctgtcattgatgcc
acaatgttcaatccttgtgggtattcgatgaatggaatgaaatcggatggaacttattgg
actattcacatcactccagaaccagaattttcttatgttagctttgaaacaaacttaagt
cagacctcctatgatgacctgatcaggaaagttgtagaagtcttcaagccaggaaaattt
gtgaccaccttgtttgttaatcagagttctaaatgtcgcacagtgcttgcttcgccccag
aagattgaaggttttaagcgtcttgattgccagagtgctatgttcaatgattacaatttt
gtttttaccagttttgctaagaagcagcaacaacagcagagttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (12)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (42)   
   RefSeq(nuc) (10)   
   GenBank (16)   
   EMBL (16)   
3D Structure (25)   
   PDB (25)   
Protein domain (1)   
   Pfam (1)   
All databases (108)   

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