KEGG   Homo sapiens (human): 2639
Entry
2639              CDS       T01001                                 
Symbol
GCDH, ACAD5, GCD
Name
(RefSeq) glutaryl-CoA dehydrogenase
  KO
K00252  glutaryl-CoA dehydrogenase [EC:1.3.8.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00071  Fatty acid degradation
hsa00310  Lysine degradation
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
Module
hsa_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Network
nt06036  Lysine degradation
  Element
N01687  Lysine degradation 3
Disease
H00178  Glutaric acidemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    2639 (GCDH)
  09105 Amino acid metabolism
   00310 Lysine degradation
    2639 (GCDH)
   00380 Tryptophan metabolism
    2639 (GCDH)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.8  With a flavin as acceptor
    1.3.8.6  glutaryl-CoA dehydrogenase (ETF)
     2639 (GCDH)
SSDB
Motif
Pfam: Acyl-CoA_dh_N Acyl-CoA_dh_1 Acyl-CoA_dh_M Acyl-CoA_dh_2
Other DBs
NCBI-GeneID: 2639
NCBI-ProteinID: NP_000150
OMIM: 608801
HGNC: 4189
Ensembl: ENSG00000105607
UniProt: Q92947
Structure
Position
19:12891129..12899999
AA seq 438 aa
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL
TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS
VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT
EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK
GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG
VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD
KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH
ALILGRAITGIQAFTASK
NT seq 1317 nt   +upstreamnt  +downstreamnt
atggccctgagaggcgtctccgtgcggctgctgagccgcggacccggcctgcacgtcctt
cgcacgtgggtctcgtcggcggcgcagaccgagaaaggcgggagaacacagagccaactg
gctaagtcctcgcgtcccgagtttgactggcaggacccgctggtgctggaggagcagctg
accacagatgagatcctcatcagggacaccttccgcacctactgccaggagagactcatg
cctcgcatcctgttggccaatcgcaacgaagtttttcatcgggagatcatttcggagatg
ggggagttgggtgtgctgggccccaccatcaaaggatatggctgtgctggggtttcgtct
gtggcctatgggctcctggcccgagagctggagcgggtggacagtggctacaggtcggcg
atgagtgtccagtcctccctcgtcatgcaccctatctatgcctatggcagcgaggaacag
cggcagaagtacctgccccagctggccaagggggagctcctgggctgcttcgggctcaca
gagcccaacagcggaagtgaccccagcagcatggagaccagagcccactacaactcatcc
aacaagagctacaccctcaatgggaccaagacctggatcacgaactcgcctatggccgat
ctgtttgtagtgtgggctcggtgtgaagatggctgcattcggggcttcctgctggagaag
gggatgcggggtctctcggcccccaggatccagggcaagttctcgctgcgggcctcagcc
acaggcatgatcatcatggacggtgtggaggtgccagaggagaatgtgctccctggtgca
tccagcctggggggtcccttcggctgcctgaacaacgcccggtacggcatcgcgtggggc
gtgcttggagcttcggagttctgcttgcacacagcccggcagtacgccctcgacaggatg
cagtttggtgtcccactggccaggaaccagctgattcagaagaagctggcagacatgctc
actgagattaccctgggccttcacgcctgcctgcagctcggccgcttgaaggaccaggac
aaggctgcccccgagatggtttctctgctgaagaggaataactgtgggaaagccctggac
atcgcccgccaggcccgagacatgctgggggggaatgggatttctgacgagtatcacgtg
atccggcacgccatgaacctggaggccgtgaacacctacgaaggtacacatgacattcac
gccctgatccttgggagagctatcacgggaatccaggcgttcacggccagcaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (106)   
   RefSeq(nuc) (4)   
   GenBank (51)   
   EMBL (51)   
3D Structure (4)   
   PDB (4)   
Protein domain (4)   
   Pfam (4)   
All databases (173)   

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