KEGG   Homo sapiens (human): 2648
Entry
2648              CDS       T01001                                 
Symbol
KAT2A, GCN5, GCN5L2, PCAF-b, hGCN5
Name
(RefSeq) lysine acetyltransferase 2A
  KO
K06062  histone acetyltransferase [EC:2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03250  Viral life cycle - HIV-1
hsa04330  Notch signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa05166  Human T-cell leukemia virus 1 infection
hsa05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    2648 (KAT2A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    2648 (KAT2A)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    2648 (KAT2A)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    2648 (KAT2A)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    2648 (KAT2A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    2648 (KAT2A)
   03036 Chromosome and associated proteins [BR:hsa03036]
    2648 (KAT2A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     2648 (KAT2A)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Coactivators
    SAGA/TFTC/STAGA complex
     2648 (KAT2A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    2648 (KAT2A)
   HAT complexes
    PCAF complex
     2648 (KAT2A)
    STAGA complex
     2648 (KAT2A)
    TFTC complex
     2648 (KAT2A)
    SAGA complex
     2648 (KAT2A)
    SLIK complex
     2648 (KAT2A)
    ADA-HAT complex
     2648 (KAT2A)
    HAT-A2 complex
     2648 (KAT2A)
    ATAC complex
     2648 (KAT2A)
SSDB
Motif
Pfam: PCAF_N Bromodomain Acetyltransf_1 Acetyltransf_7 Acetyltransf_10
Other DBs
NCBI-GeneID: 2648
NCBI-ProteinID: NP_066564
OMIM: 602301
HGNC: 4201
Ensembl: ENSG00000108773
UniProt: Q92830
Structure
Position
17:complement(42113111..42121367)
AA seq 837 aa
MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT
GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC
NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE
NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ
YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH
VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL
SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS
LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL
SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA
RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE
YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP
YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG
KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE
RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK
NT seq 2514 nt   +upstreamnt  +downstreamnt
atggcggaaccttcccaggccccgaccccggccccggctgcgcagccccggccccttcag
tccccagcccctgccccaactccgactcctgcacccagcccggcttcagccccgattccg
actcccaccccggcaccagcccctgccccagctgcagccccagccggcagcacagggact
ggggggcccggggtaggaagtgggggggccgggagcgggggggatccggctcgacctggc
ctgagccagcagcagcgcgccagtcagaggaaggcgcaagtccgggggctgccgcgcgcc
aagaagcttgagaagctaggggtcttctcggcttgcaaggccaatgaaacctgtaagtgt
aatggctggaaaaaccccaagccccccactgcaccccgcatggatctgcagcagccagct
gccaacctgagtgagctgtgccgcagttgtgagcaccccttggctgaccacgtatcccac
ttggagaatgtgtcagaggatgagataaaccgactgctggggatggtggtggatgtggag
aatctcttcatgtctgttcacaaggaagaggacacagacaccaagcaggtctatttctac
ctcttcaagctactgcggaaatgcatcctgcagatgacccggcctgtggtggaggggtcc
ctgggcagccctccatttgagaaacctaatattgagcagggtgtgctgaactttgtgcag
tacaagtttagtcacctggctccccgggagcggcagacgatgttcgagctctcaaagatg
ttcttgctctgccttaactactggaagcttgagacacctgcccagtttcggcagaggtct
caggctgaggacgtggctacctacaaggtcaattacaccagatggctctgttactgccac
gtgccccagagctgtgatagcctcccccgctacgaaaccactcatgtctttgggcgaagc
cttctccggtccattttcaccgttacccgccggcagctgctggaaaagttccgagtggag
aaggacaaattggtgcccgagaagaggaccctcatcctcactcacttccccaaattcctg
tccatgctggaggaggagatctatggggcaaactctccaatctgggagtcaggcttcacc
atgccaccctcagaggggacacagctggttccccggccagcttcagtcagtgcagcggtt
gttcccagcacccccatcttcagccccagcatgggtgggggcagcaacagctccctgagt
ctggattctgcaggggccgagcctatgccaggcgagaagaggacgctcccagagaacctg
accctggaggatgccaagcggctccgtgtgatgggtgacatccccatggagctggtcaat
gaggtcatgctgaccatcactgaccctgctgccatgctggggcctgagacgagcctgctt
tcggccaatgcggcccgggatgagacagcccgcctggaggagcgccgcggcatcatcgag
ttccatgtcatcggcaactcactgacgcccaaggccaaccggcgggtgttgctgtggctc
gtggggctgcagaatgtcttttcccaccagctgccgcgcatgcctaaggagtatatcgcc
cgcctcgtctttgacccgaagcacaagactctggccttgatcaaggatgggcgggtcatc
ggtggcatctgcttccgcatgtttcccacccagggcttcacggagattgtcttctgtgct
gtcacctcgaatgagcaggtcaagggttatgggacccacctgatgaaccacctgaaggag
tatcacatcaagcacaacattctctacttcctcacctacgccgacgagtacgccatcggc
tacttcaaaaagcagggtttctccaaggacatcaaggtgcccaagagccgctacctgggc
tacatcaaggactacgagggagcgacgctgatggagtgtgagctgaatccccgcatcccc
tacacggagctgtcccacatcatcaagaagcagaaagagatcatcaagaagctgattgag
cgcaaacaggcccagatccgcaaggtctacccggggctcagctgcttcaaggagggcgtg
aggcagatccctgtggagagcgttcctggcattcgagagacaggctggaagccattgggg
aaggagaaggggaaggagctgaaggaccccgaccagctctacacaaccctcaaaaacctg
ctggcccaaatcaagtctcaccccagtgcctggcccttcatggagcctgtgaagaagtcg
gaggcccctgactactacgaggtcatccgcttccccattgacctgaagaccatgactgag
cggctgcgaagccgctactacgtgacccggaagctctttgtggccgacctgcagcgggtc
atcgccaactgtcgcgagtacaaccccccggacagcgagtactgccgctgtgccagcgcc
ctggagaagttcttctacttcaagctcaaggagggaggcctcattgacaagtag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
3D Structure (13)   
   PDB (13)   
Protein domain (5)   
   Pfam (5)   
All databases (73)   

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