KEGG   Homo sapiens (human): 27072
Entry
27072             CDS       T01001                                 
Symbol
VPS41, HVPS41, HVSP41, SCAR29, hVps41p
Name
(RefSeq) VPS41 subunit of HOPS complex
  KO
K20184  vacuolar protein sorting-associated protein 41
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04148  Efferocytosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06532  Autophagy
  Element
N01300  Tethering of late endosomes and lysosomes
N01301  Salmonella SifA to Tethering of late endosomes and lysosomes
N01721  Autophagosome and lysosome fusion, tethering factor
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    27072 (VPS41)
   04148 Efferocytosis
    27072 (VPS41)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    27072 (VPS41)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    27072 (VPS41)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Tethering complex
   Hops complex
    27072 (VPS41)
SSDB
Motif
Pfam: Clathrin ANAPC4_WD40 Vps39_2 Vps39_1 zf-RING_5 Frtz RIG-I_C zf-RING_2 zf-rbx1
Other DBs
NCBI-GeneID: 27072
NCBI-ProteinID: NP_055211
OMIM: 605485
HGNC: 12713
Ensembl: ENSG00000006715
UniProt: P49754
Position
7:complement(38722974..38909191)
AA seq 854 aa
MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH
ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
KNRGPGSAILEMKK
NT seq 2565 nt   +upstreamnt  +downstreamnt
atggcggaagcagaggagcaggaaactgggtcccttgaagaatctacagatgagtctgag
gaagaagagagcgaagaggaacccaagctgaagtatgaaaggctttccaatggggtaact
gaaatacttcagaaggatgcagctagctgcatgacagtccatgacaagtttttggcattg
ggcacacattatggcaaggtttatttacttgatgtccaggggaacatcactcagaagttt
gatgtaagtcctgtgaagataaatcagattagcttggatgaaagtggagagcacatgggt
gtgtgttcagaggatggcaaggtgcaggtatttggactgtattctggagaagaatttcac
gagacttttgactgtcccattaaaattattgctgtgcacccacatttcgtgagatccagt
tgcaagcagtttgtgaccggagggaagaagctgctactgtttgaacggtcttggatgaac
agatggaagtctgctgttctgcatgaaggggaagggaacataaggagtgtgaagtggaga
ggccatctgattgcttgggccaataatatgggtgtgaagatttttgacatcatctcaaag
caaagaatcaccaatgtgccccgggatgatataagtcttcgcccagacatgtatccctgc
agcctctgctggaaggacaatgtgacactgattattggctgggggacttctgtcaaggtg
tgctcagtgaaggaacggcatgccagtgaaatgagggatttgccaagtcgatatgttgaa
atagtgtctcagtttgaaactgaattctacatcagtggacttgcacctctctgtgatcag
cttgttgtactttcgtatgtaaaggagatttcagaaaaaacggaaagagaatactgtgcc
aggcctagactggacatcatccagccactttctgagacttgtgaagagatctcttctgat
gctttgacagtcagaggctttcaggagaatgaatgtagagattatcatttagaatactct
gaaggggaatcacttttttacatcgtgagtccgagagatgttgtagtggccaaggaacga
gaccaagatgatcacattgactggctccttgaaaagaagaaatatgaagaagcattgatg
gcagctgaaattagccaaaaaaatattaaaagacataagattctggatattggcttggca
tatataaatcacctggtggagagaggagactatgacatagcagcacgcaaatgccagaaa
attcttgggaaaaatgcagcactctgggaatatgaagtttataaatttaaagaaattgga
cagcttaaggctattagtccttatttgccaagaggtgatccagttctgaaaccactcatc
tatgaaatgatcttacatgaatttttggagagtgattatgagggttttgccacattgatc
cgagaatggcctggagatctgtataataattcagtcatagttcaagcagttcgggatcat
ttgaagaaagatagtcagaacaagactttacttaaaaccctggcagaattgtacacctat
gacaagaactatggcaatgctctggaaatatacttaacattaagacataaagacgttttt
cagttgatccacaagcataatcttttcagttctatcaaggataaaattgttttattaatg
gattttgattcagagaaagctgttgacatgcttttggacaatgaagataaaatttcaatt
aaaaaggtagtggaagaattggaagacagaccagagctacagcatgtgtatttgcataag
cttttcaagagagaccaccataaggggcagcgttaccatgaaaaacagatcagtctttat
gctgaatatgatcgaccaaacttacttccctttctccgagacagtacccattgcccactt
gaaaaggctcttgagatctgtcaacagagaaactttgtagaagagacagtttatcttctg
agccgaatgggtaatagccgaagtgccctgaagatgattatggaggaattacatgatgtt
gataaagcaatcgaatttgccaaggagcaagatgatggagagctgtgggaagatttgatt
ttatattccattgacaaaccaccatttattactggcttgttaaacaacattggcacacat
gttgacccaattctactgattcaccgtattaaggaaggaatggagatccccaatttgaga
gattccttggttaaaattctgcaagactacaatttgcaaattctgcttcgtgaaggctgc
aagaagattctcgtagctgactctttgtccttactgaagaaaatgcaccgaactcaaatg
aaaggtgttcttgttgatgaggagaacatctgtgagtcgtgcctttcccctattcttcca
tcagatgcagctaagcccttcagcgtggtggtcttccattgccggcacatgttccacaag
gagtgcctgcccatgcccagcatgaactctgctgcacagttctgcaacatctgcagtgct
aagaaccgtggaccaggaagtgcaattttggagatgaaaaaatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (5)   
   KEGG NETWORK (5)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (24)   
   RefSeq(nuc) (6)   
   GenBank (9)   
   EMBL (9)   
Protein domain (9)   
   Pfam (9)   
All databases (67)   

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