KEGG   Homo sapiens (human): 27125
Entry
27125             CDS       T01001                                 
Symbol
AFF4, AF5Q31, CHOPS, MCEF
Name
(RefSeq) ALF transcription elongation factor 4
  KO
K15185  AF4/FMR2 family member 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03250  Viral life cycle - HIV-1
Disease
H01569  CHOPS syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    27125 (AFF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    27125 (AFF4)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Super elongation complex (SEC)
     27125 (AFF4)
SSDB
Motif
Pfam: AF-4 AFF4_CHD AF4_int
Other DBs
NCBI-GeneID: 27125
NCBI-ProteinID: NP_055238
OMIM: 604417
HGNC: 17869
Ensembl: ENSG00000072364
UniProt: Q9UHB7
Structure
Position
5:complement(132875395..132963634)
AA seq 1163 aa
MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYD
EMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS
QKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSS
PGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP
SLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI
PSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG
EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG
ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK
VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS
ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR
HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP
PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDL
NLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESK
KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSS
LKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK
PRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNA
QESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKEN
ALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASG
SSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASI
MTDLVRYTRQGLHWLRQDAKLIS
NT seq 3492 nt   +upstreamnt  +downstreamnt
atgaaccgtgaagaccggaatgtgctgcgtatgaaagaacgggaaaggcggaatcaggaa
attcagcagggcgaagacgccttcccacctagctctcctctctttgcagagccatacaaa
gttactagcaaagaagataagttatcaagtcgtattcagagtatgcttggaaactacgat
gaaatgaaggatttcataggagacagatctataccaaagcttgttgcaattcccaagcct
acagtaccaccatcagcagatgaaaaatctaacccaaatttctttgaacagagacatgga
ggctctcatcagagtagcaaatggactccagtaggacccgcacccagcacttctcagtct
cagaaacggtcctcaggcttacagagtggacatagtagccagcggaccagcgcaggtagc
agtagtggcactaacagtagtggtcagaggcacgaccgtgagtcatataacaatagtggg
agcagtagccggaaaaaaggccagcatggatcagaacactccaaatcacgttcttccagc
cctggaaaaccccaggctgtttcttcattaaactctagtcattccaggtctcatgggaat
gatcaccatagcaaggaacatcaacgctccaaatcacctcgggaccctgatgcaaactgg
gattctccttcccgtgtacctttttcaagtgggcagcactcaactcaatctttcccaccc
tcattgatgtcaaagtccaattcaatgttacagaaacccactgcctatgtgcggcccatg
gacggacaggagtccatggaaccaaagctgtcctctgagcactacagcagccaatcccat
ggcaacagcatgactgagctgaagcccagcagcaaagcacatctcaccaagctgaaaata
ccttcccaaccactggatgcatcagcttctggtgatgtgagctgtgtggatgaaatccta
aaagagatgacgcattcatggcctccccctctaacggctattcatacaccatgcaaaaca
gaaccttccaaatttccttttccaactaaggagtctcagcagtccaattttggcactgga
gaacaaaaaagatataatccttctaaaacttcaaatgggcaccagtctaaatctatgtta
aaagatgacttaaaactaagcagcagtgaagacagtgatggggaacaggattgtgataag
acaatgccgaggagtacaccaggaagtaactctgaaccttcacaccataatagtgaagga
gcagataactccagggatgattctagtagccacagtggatctgaaagcagctctggatct
gactcagagagtgaaagtagttccagtgacagtgaggcaaatgagccatcccagagtgca
tctcccgagcctgaacccccgccaacaaacaaatggcaacttgataattggctgaataaa
gtgaacccacataaagtgtcacccgcctcttcagtggacagtaacatcccatcatctcaa
ggctacaaaaaggaaggccgagagcagggcactgggaatagctacactgatacaagtgga
cctaaagaaacgagttccgctactccgggacgagactccaaaaccatccaaaagggatca
gaaagtgggcgtgggaggcagaaatctcctgcacagagtgacagcacaacacagagaaga
actgtaggcaaaaaacaacccaaaaaggctgagaaggcagctgctgaagagcctcgtgga
ggcctgaagatagaaagtgaaacccctgtagacttggctagcagcatgccctccagcaga
cacaaagcagccaccaaaggctcaaggaaacccaatataaagaaggagtctaagtcttcc
cctcgacctacagcagagaaaaagaaatataagtcaacaagtaaatcttcccagaaatca
agggaaatcatagaaacagatacctcatcctcagattcagatgaaagtgagagccttcct
ccttcctcacaaactcctaagtaccccgagagcaataggactcctgttaaaccctcctca
gtggaggaagaagatagcttttttcggcaacgaatgttctctcctatggaagagaaggaa
cttctttcacccctcagtgagcctgatgacaggtacccacttattgtgaagattgacctg
aatcttttgactagaataccaggaaagccttacaaagaaacagagccgcccaagggggaa
aagaaaaatgtgccagaaaagcacacgagagaggctcagaaacaagcctcagaaaaagtt
tccaacaaaggcaagaggaagcataagaatgaagatgataaccgagccagtgagagcaag
aaacccaaaacggaggacaagaattcagcaggccataagccatccagcaacagagagtca
tctaagcagagtgctgcaaaagaaaaggatttgttgccttctcccgctgggcctgttcct
tcaaaagatccaaaaacagagcatggctctcggaagaggactattagtcagtcttcttcc
ttaaagtcaagcagtaacagcaacaaggagacgagtggcagcagcaaaaacagttcctcc
acatcaaagcagaagaagaccgaagggaagacttccagtagctccaaggaggttaaggaa
aaggctccaagtagctcctctaactgtcctccatctgcaccaactcttgattcttctaag
cctcggagaacaaagcttgtctttgatgacagaaattattcagcagaccattatttacaa
gaagcaaaaaagctaaagcacaatgcagatgcattgtctgataggtttgagaaagctgta
tactatcttgatgctgtggtatctttcattgaatgtgggaatgcattagagaagaatgct
caggaatccaaatccccattccctatgtattcagagacggtggatctcatcaaatacact
atgaagctaaagaattacttggcaccagatgctacagctgcagataaacgactcacagta
ctttgcctgcgatgcgagtctttgctgtacctgaggctgttcaaactgaagaaggaaaat
gctctgaagtactcaaagacactgacagagcacctgaagaattcttataataattctcaa
gcaccatcgcctggcttgggaagcaaagctgtggggatgccttcccctgtttctccaaag
ctgtcaccaggcaattcaggaaattattcatctggggccagtagtgcttctgcaagtggt
tcttcagtgaccattccacagaagatccaccagatggcagccagctatgttcaggtcaca
tccaacttcctctatgccaccgaaatttgggaccaagctgaacagctttccaaagagcaa
aaagaattctttgctgaactggataaagtaatgggccctctcatctttaatgcaagcatc
atgacagatctagttcgttatacccggcagggactgcactggcttcgccaggatgccaag
ttgatatcttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (13)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (45)   
   RefSeq(nuc) (9)   
   GenBank (18)   
   EMBL (18)   
3D Structure (9)   
   PDB (9)   
Protein domain (3)   
   Pfam (3)   
All databases (113)   

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