KEGG   Homo sapiens (human): 27329
Entry
27329             CDS       T01001                                 
Symbol
ANGPTL3, ANG-5, ANGPT5, ANL3, FHBL2
Name
(RefSeq) angiopoietin like 3
  KO
K22288  angiopoietin-like 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04979  Cholesterol metabolism
Disease
H01270  Familial hypobetalipoproteinemia
Drug target
Evinacumab: D11753<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    27329 (ANGPTL3)
SSDB
Motif
Pfam: Fibrinogen_C FAM186A-B_C Crescentin DUF4201 DUF3209 ISG65-75 DUF1664
Other DBs
NCBI-GeneID: 27329
NCBI-ProteinID: NP_055310
OMIM: 604774
HGNC: 491
Ensembl: ENSG00000132855
UniProt: Q9Y5C1
Structure
Position
1:62597520..62606313
AA seq 460 aa
MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDF
VHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLEL
NSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQ
TVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHD
GIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWE
NYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTL
HLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKP
RAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgttcacaattaagctccttctttttattgttcctctagttatttcctccagaattgat
caagacaattcatcatttgattctctatctccagagccaaaatcaagatttgctatgtta
gacgatgtaaaaattttagccaatggcctccttcagttgggacatggtcttaaagacttt
gtccataagacgaagggccaaattaatgacatatttcaaaaactcaacatatttgatcag
tctttttatgatctatcgctgcaaaccagtgaaatcaaagaagaagaaaaggaactgaga
agaactacatataaactacaagtcaaaaatgaagaggtaaagaatatgtcacttgaactc
aactcaaaacttgaaagcctcctagaagaaaaaattctacttcaacaaaaagtgaaatat
ttagaagagcaactaactaacttaattcaaaatcaacctgaaactccagaacacccagaa
gtaacttcacttaaaacttttgtagaaaaacaagataatagcatcaaagaccttctccag
accgtggaagaccaatataaacaattaaaccaacagcatagtcaaataaaagaaatagaa
aatcagctcagaaggactagtattcaagaacccacagaaatttctctatcttccaagcca
agagcaccaagaactactccctttcttcagttgaatgaaataagaaatgtaaaacatgat
ggcattcctgctgaatgtaccaccatttataacagaggtgaacatacaagtggcatgtat
gccatcagacccagcaactctcaagtttttcatgtctactgtgatgttatatcaggtagt
ccatggacattaattcaacatcgaatagatggatcacaaaacttcaatgaaacgtgggag
aactacaaatatggttttgggaggcttgatggagaattttggttgggcctagagaagata
tactccatagtgaagcaatctaattatgttttacgaattgagttggaagactggaaagac
aacaaacattatattgaatattctttttacttgggaaatcacgaaaccaactatacgcta
catctagttgcgattactggcaatgtccccaatgcaatcccggaaaacaaagatttggtg
ttttctacttgggatcacaaagcaaaaggacacttcaactgtccagagggttattcagga
ggctggtggtggcatgatgagtgtggagaaaacaacctaaatggtaaatataacaaacca
agagcaaaatctaagccagagaggagaagaggattatcttggaagtctcaaaatggaagg
ttatactctataaaatcaaccaaaatgttgatccatccaacagattcagaaagctttgaa
tga

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (56)   

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