KEGG   Homo sapiens (human): 286
Entry
286               CDS       T01001                                 
Symbol
ANK1, ANK, SPH1, SPH2, ankyrin-1
Name
(RefSeq) ankyrin 1
  KO
K10380  ankyrin-1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05205  Proteoglycans in cancer
Disease
H00230  Hereditary spherocytosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    286 (ANK1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    286 (ANK1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filament-binding proteins
    286 (ANK1)
SSDB
Motif
Pfam: Ank Ank_2 Ank_4 Ank_3 Ank_5 UPA_2 ZU5 Death
Other DBs
NCBI-GeneID: 286
NCBI-ProteinID: NP_065209
OMIM: 612641
HGNC: 492
Ensembl: ENSG00000029534
UniProt: P16157
Structure
Position
8:complement(41653225..41896741)
AA seq 1881 aa
MPYSVGFREADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKM
VVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQ
ENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIA
ARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI
TPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA
KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK
GAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIV
KNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARI
GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL
HVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAW
NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN
GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL
LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYI
SVTDVLKVVTDETSFVLVSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEE
KELLDFVPKLDQVVESPAIPRIPCAMPETVVIRSEEQEQASKEYDEDSLIPSSPATETSD
NISPVASPVHTGFLVSFMVDARGGSMRGSRHNGLRVVIPPRTCAAPTRITCRLVKPQKLS
TPPPLAEEEGLASRIIALGPTGAQFLSPVIVEIPHFASHGRGDRELVVLRSENGSVWKEH
RSRYGESYLDQILNGMDEELGSLEELEKKRVCRIITTDFPLYFVIMSRLCQDYDTIGPEG
GSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATFSPIVTVEPRRRK
FHRPIGLRIPLPPSWTDNPRDSGEGDTTSLRLLCSVIGGTDQAQWEDITGTTKLVYANEC
ANFTTNVSARFWLSDCPRTAEAVNFATLLYKELTAVPYMAKFVIFAKMNDPREGRLRCYC
MTDDKVDKTLEQHENFVEVARSRDIEVLEGMSLFAELSGNLVPVKKAAQQRSFHFQSFRE
NRLAMPVKVRDSSREPGGSLSFLRKAMKYEDTQHILCHLNITMPPCAKGSGAEDRRRTPT
PLALRYSILSESTPGSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENP
NSLLEQSVALLNLWVIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHT
DRDYSLSPSQMNGYSSLQDELLSPASLGCALSSPLRADQYWNEVAVLDAIPLAATEHDTM
LEMSDMQVWSAGLTPSLVTAEDSSLECSKAEDSDATGHEWKLEGALSEEPRGPELGSLEL
VEDDTVDSDATNGLIDLLEQEEGQRSEEKLPGSKRQDDATGAGQDSENEVSLVSGHQRGQ
ARITHSPTVSQVTERSQDRLQDWDADGSIVSYLQDAAQGSWQEEVTQGPHSFQGTSTMTE
GLEPGGSQEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTFTQVVQGN
EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVTVEGPLEDPSE
LEVDIDYFMKHSKDHTSTPNP
NT seq 5646 nt   +upstreamnt  +downstreamnt
atgccctattctgtgggcttccgcgaagccgatgctgctaccagctttctgagagcagca
agatcaggtaacttggacaaagctttggatcacctgcggaatggggtagatattaacacc
tgtaaccagaatgggttgaatggcttgcatctggcttctaaggaaggccatgtgaaaatg
gtggttgaacttctgcacaaagaaatcattctagaaacgacaaccaagaaggggaacacg
gccctgcacatcgctgctctagccgggcaggatgaggtggtccgggagcttgtcaactat
ggagccaacgtcaacgcccagtcacagaaaggttttacacccctgtacatggcagcacaa
gagaaccacttggaagtggttaagtttttactggaaaatggagctaaccagaatgtagcc
acagaagacggcttcacgcctctggcggtagccctgcagcagggccatgagaacgtcgtc
gcgcacctcatcaactacggcaccaaggggaaggtgcgcctcccggccctgcacatcgcg
gcccgcaacgacgacacgcgcacggctgcggtgctgctgcagaacgaccccaacccggac
gtgctttccaagacgggattcacgcccctgcacattgcggctcactacgagaacctcaac
gtggcccagttgctcctcaacagaggagccagcgtcaatttcacaccacagaacggcatc
acgccactgcacatcgcctcccgcaggggcaacgtgatcatggtgcggctgctgctggat
cggggagcccagatagaaaccaagaccaaggacgaattgacacctctccactgtgcagct
cgaaatgggcacgtgcgaatctcagagatcctgctggaccacggggcaccaatccaagcc
aaaaccaagaacggcctgtccccaattcacatggcggctcagggagaccacctcgactgt
gtccggctcctgttgcaatacgacgcagagatagacgacatcaccctggaccacctgacc
ccactccacgtggctgcccactgtggacaccacagggtggctaaggtccttctggataaa
ggggccaaacccaactccagagccctgaatggctttacccccttacacatcgcctgcaaa
aagaaccacgtccgtgtcatggagctgctgctgaagacgggagcctcgatcgacgcggtc
accgagtctggcctgacacctctccacgtggcctccttcatggggcaccttcccatcgtg
aagaacctcctgcagcggggggcgtcgcccaacgtctccaacgtgaaagtggagaccccg
ctacacatggcagccagagccgggcacacggaagtggccaaatatttactccagaacaaa
gccaaagtcaatgccaaggccaaggatgaccagaccccacttcactgtgcagctcgcatc
ggccacacaaacatggtgaagctcctgctggaaaataacgccaaccccaacctggccacc
accgccgggcacacccccctgcacattgcagcccgtgagggccatgtggaaacagtcctg
gcccttctggaaaaggaagcatcccaggcctgcatgaccaagaaaggatttacccctctg
cacgtggcggccaagtacgggaaggtgcgggtggcagagctgctgctggagcgggacgca
cacccgaatgctgccggaaaaaatggcctgacccccctgcacgtggccgtccatcacaac
aacctggacatcgtcaagctgctgcttccccggggcggctccccgcacagccctgcctgg
aatggctacacccctttgcacatcgctgccaagcagaaccaggtggaggtggcccgtagt
ctgctgcagtatgggggctcagcaaacgccgagtcggtgcaaggtgtgacgccccttcac
ctggccgcccaggagggccacgcagagatggtggctctgctgctctcgaaacaagccaat
ggcaacctggggaacaagagcggactcactcccctccatctggtagcacaagaaggccac
gttccagtggcagatgtgctgatcaaacacggcgtcatggtggacgccaccacccggatg
ggctacactcccctccatgtggccagtcactatggaaacatcaagctggtgaagtttctg
ctgcagcaccaggcagatgtcaatgccaagaccaagctaggatacagccccctgcaccag
gcagcccagcagggacacacagacatcgtgactctgcttctgaaaaacggtgcttcccca
aacgaggtcagctcggatggaaccacacctctggccatagccaagcgcttgggctacatt
tctgtcaccgacgtgctcaaggtcgtcacggatgaaaccagtttcgtgttagtcagtgat
aagcatcgaatgagtttccctgagacagttgatgagatcctggatgtctcggaagatgaa
ggggaagaactcatcagcttcaaggctgagaggcgggattccagggatgttgatgaagag
aaggagctgctggattttgtgccgaagctagaccaagtggtggaatctccagccatcccc
aggattccctgtgccatgcctgagacagtggtgatcaggtcagaagagcaggagcaggca
tctaaagagtatgatgaggactccctcatccccagcagcccggccaccgagacctcagac
aacatcagcccggtggccagcccggtgcatacagggtttctggtgagcttcatggttgac
gcccggggtggttccatgagaggaagtcgccacaacggcctgcgagtggtgatcccgcca
cggacgtgcgcagcgcccacccgcatcacctgccgcctggtcaagccccagaagctcagc
acgccgcccccactggccgaggaggagggcctggccagcaggatcatagcactggggccc
acgggggcacagttcctgagccctgtaatcgtggagatcccgcactttgcctcccatggc
cgtggagaccgcgagctcgtggttctgaggagcgaaaacggctccgtgtggaaggagcac
aggagccgctatggagagagctacctggatcagatcctcaacgggatggacgaagagctg
gggagcctggaggagctagagaagaagagggtgtgccgaatcatcaccaccgacttcccg
ctgtacttcgtgatcatgtcacggctctgccaggactacgacaccatcggtcccgaaggg
ggctccctgaagagcaagctggtgcccctggtacaggcaacgttcccggagaatgccgtc
accaagagagtgaagctggctctgcaggcccagcctgtcccggatgagcttgtcactaag
ctcctgggcaaccaggccacattcagccccattgtcaccgtggagccccggcgccggaag
ttccaccgccccattgggcttcggatcccactacctccttcctggaccgacaacccgagg
gacagcggggagggagacaccaccagcctgcgcctgctttgcagcgtcattggaggaaca
gaccaagcccagtgggaagacataacaggaaccaccaaacttgtatatgccaacgagtgc
gccaacttcaccaccaatgtctctgccaggttttggctgtcggactgtcctcggactgct
gaggctgtgaactttgccaccctgctgtacaaagagctcactgcagtgccctacatggcc
aaattcgtcatctttgccaagatgaatgacccccgagaggggcgcctgcgctgctactgc
atgacagatgataaagtggacaagaccctggagcagcatgagaacttcgtggaggtggcc
cggagcagggacatagaggtgttggaaggaatgtccctgtttgcagaactctctgggaac
ctggtgcctgtgaagaaagctgcccagcagcggagcttccacttccagtcatttcgggag
aaccgtctggccatgcctgtaaaggtgagggacagcagtcgagagccgggagggtccctg
tcgtttctgcgcaaggcgatgaagtacgaggacacccagcacattctctgccacctgaac
atcaccatgcccccctgcgccaagggaagtggagccgaagataggagaaggaccccgacg
cccctggccctgcgatacagcattctcagtgagtccacaccaggttctctcagtgggaca
gagcaggcagagatgaagatggctgttatctcagagcacctcggtctcagctgggcagag
ttggcccgggagctgcagttcagtgtggaagacatcaacaggatccgagtggaaaatccc
aactccctgttggagcagagtgtggccttgctgaacctctgggtcatccgtgaaggccaa
aacgcaaacatggagaatctgtacacagccctgcagagcattgaccgtggcgagatcgtg
aacatgctggagggttccggccgacagagccgcaacttgaagccagacaggcggcacacc
gaccgcgactactcgctgtcaccctcccagatgaatggttactcctcactgcaggacgag
ctgctgtcccctgcctccctgggctgtgcactttcctctccgctacgtgcagaccagtac
tggaatgaggtggccgtcctagacgccatccccttggcggccacggagcatgacaccatg
ctggagatgtctgacatgcaggtgtggtctgcgggcctcacgccttctctggtcactgct
gaggactcctctctggagtgtagcaaggctgaggactctgatgccacaggtcacgagtgg
aagttggagggggcactctcagaggaaccgcggggccccgagttgggctctctggaactt
gtggaggacgacacagtggattcagatgccacaaatggccttatcgatttgcttgaacag
gaggaaggtcagaggtcagaagagaagctgccaggttctaagaggcaggatgacgcgaca
ggtgcagggcaggactcagagaatgaagtgtctcttgtttcaggccatcagagggggcaa
gcccgaatcacacattcccccaccgtgagtcaggtgacggagaggagtcaggacagactg
caggactgggatgcagacggctcgattgtctcatacctgcaagatgctgcacaaggttcc
tggcaagaggaggtcacgcaaggtccacactcattccagggaacaagtaccatgactgaa
gggctagagcccggtggatctcaggagtacgagaaggtcctggtgtctgtaagtgagcac
acgtggacagaacagcccgaggctgagagctcccaggccgacagggaccggaggcagcaa
ggccaagaagagcaggtgcaggaggccaagaacaccttcacccaagtggtgcaggggaat
gagtttcagaatattccaggggagcaggtgacagaggagcaattcacggatgagcagggc
aacattgtcaccaagaagatcattcgcaaggtggttcgacagatagacttgtccagcgcc
gatgccgcccaggagcacgaggaggtgactgtagaggggcccctggaggatcccagtgag
ctggaggtcgatattgattactttatgaaacactccaaggatcacacctcgacacccaac
ccctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (56)   
   RefSeq(nuc) (10)   
   GenBank (23)   
   EMBL (23)   
3D Structure (21)   
   PDB (21)   
Protein domain (8)   
   Pfam (8)   
All databases (133)   

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