KEGG   Homo sapiens (human): 2875
Entry
2875              CDS       T01001                                 
Symbol
GPT, AAT1, ALT, ALT1, GPT1, SGPT
Name
(RefSeq) glutamic--pyruvic transaminase
  KO
K00814  alanine transaminase [EC:2.6.1.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00220  Arginine biosynthesis
hsa00250  Alanine, aspartate and glutamate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    2875 (GPT)
   00220 Arginine biosynthesis
    2875 (GPT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    2875 (GPT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.2  alanine transaminase
     2875 (GPT)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   2875 (GPT)
SSDB
Motif
Pfam: Aminotran_1_2
Other DBs
NCBI-GeneID: 2875
NCBI-ProteinID: NP_005300
OMIM: 138200
HGNC: 4552
Ensembl: ENSG00000167701
UniProt: P24298
Position
8:144503068..144507172
AA seq 496 aa
MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPF
TEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSL
GAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRT
GVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVI
NPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPY
AGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDL
VVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQL
PPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLL
LEKLSRFHAKFTLEYS
NT seq 1491 nt   +upstreamnt  +downstreamnt
atggcctcgagcacaggtgaccggagccaggcggtgaggcatggactgagggcgaaggtg
ctgacgctggacggcatgaacccgcgtgtgcggagagtggagtacgcagtgcgtggcccc
atagtgcagcgagccttggagctggagcaggagctgcgccagggtgtgaagaagcctttc
accgaggtcatccgtgccaacatcggggacgcacaggctatggggcagaggcccatcacc
ttcctgcgccaggtcttggccctctgtgttaaccctgatcttctgagcagccccaacttc
cctgacgatgccaagaaaagggcggagcgcatcttgcaggcgtgtgggggccacagtctg
ggggcctacagcgtcagctccggcatccagctgatccgggaggacgtggcgcggtacatt
gagaggcgtgacggaggcatccctgcggaccccaacaacgtcttcctgtccacaggggcc
agcgatgccatcgtgacggtgctgaagctgctggtggccggcgagggccacacacgcacg
ggtgtgctcatccccatcccccagtacccactctactcggccacgctggcagagctgggc
gcagtgcaggtggattactacctggacgaggagcgtgcctgggcgctggacgtggccgag
cttcaccgtgcactgggccaggcgcgtgaccactgccgccctcgtgcgctctgtgtcatc
aaccctggcaaccccaccgggcaggtgcagacccgcgagtgcatcgaggccgtgatccgc
ttcgccttcgaagagcggctctttctgctggcggacgaggtgtaccaggacaacgtgtac
gccgcgggttcgcagttccactcattcaagaaggtgctcatggagatggggccgccctac
gccgggcagcaggagcttgcctccttccactccacctccaagggctacatgggcgagtgc
gggttccgcggcggctatgtggaggtggtgaacatggacgctgcagtgcagcagcagatg
ctgaagctgatgagtgtgcggctgtgcccgccggtgccaggacaggccctgctggacctg
gtggtcagcccgcccgcgcccaccgacccctcctttgcgcagttccaggctgagaagcag
gcagtgctggcagagctggcggccaaggccaagctcaccgagcaggtcttcaatgaggct
cctggcatcagctgcaacccagtgcagggcgccatgtactccttcccgcgcgtgcagctg
cccccgcgggcggtggagcgcgctcaggagctgggcctggcccccgatatgttcttctgc
ctgcgcctcctggaggagaccggcatctgcgtggtgccagggagcggctttgggcagcgg
gaaggcacctaccacttccggatgaccattctgccccccttggagaaactgcggctgctg
ctggagaagctgagcaggttccatgccaagttcaccctcgagtactcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (5)   
   GenBank (8)   
   EMBL (8)   
Protein domain (1)   
   Pfam (1)   
All databases (68)   

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