KEGG   Homo sapiens (human): 28960
Entry
28960             CDS       T01001                                 
Symbol
DCPS, ARS, DCS1, HINT-5, HINT5, HSL1, HSPC015
Name
(RefSeq) decapping enzyme, scavenger
  KO
K12584  m7GpppX diphosphatase [EC:3.6.1.59]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H01878  Al-Raqad syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    28960 (DCPS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    28960 (DCPS)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.59  5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase
     28960 (DCPS)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   5'-3' decay
    Other 5'-3' decay factors
     28960 (DCPS)
   3'-5' decay
    Other 3'-5' decay factors
     28960 (DCPS)
SSDB
Motif
Pfam: DcpS_C DcpS
Other DBs
NCBI-GeneID: 28960
NCBI-ProteinID: NP_054745
OMIM: 610534
HGNC: 29812
Ensembl: ENSG00000110063
UniProt: Q96C86 A0A384MTI8
Structure
Position
11:126304060..126350005
AA seq 337 aa
MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDK
IIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFP
PRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNIL
DKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPL
LRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAE
VIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS
NT seq 1014 nt   +upstreamnt  +downstreamnt
atggcggacgcagctcctcaactaggcaagaggaagcgcgaattggacgtggaggaggcc
cacgccgccagcacagaggaaaaggaggcaggagttggaaatggtacctgtgctcctgtc
cgcttaccgttctccggcttcagactgcagaaggtgctgagggagtctgcgcgggacaaa
atcattttcctacacgggaaggtgaatgaggcctctggggatggggatggagaggatgcc
gttgtgatcctggagaagacgccatttcaggtggaacaggtggctcagctcctgacgggc
agccctgagctccagttgcagttctccaatgatatctacagcacctatcacttgttccct
ccaagacaactgaatgatgtaaagacgaccgtggtttaccctgccacagagaaacacctg
cagaagtacctgcgccaggacctccgcctgatccgagagacgggagatgactacaggaat
attactttaccccacctggagtcccagagcctcagcatccagtgggtgtataacattctc
gacaagaaggctgaagcggaccggattgttttcgagaacccagatccctctgatggtttt
gtcctcatccctgacctcaagtggaaccaacagcagctcgatgacttgtacttgatcgcc
atctgccatcgccggggcatcagatccctacgcgaccttactccggagcacttgccgctg
ctcaggaacatcctccaccaggggcaggaggccatcctgcagcgctaccggatgaaggga
gaccatctgcgagtatacctgcactacctgccctcctactaccacctgcatgtgcacttc
accgccctgggcttcgaggcccccggctcaggcgtggagcgggcccacctgctggctgag
gtgatcgagaacttggagtgtgaccctaggcactaccagcagcgcacgctcaccttcgcc
ctcagggctgacgaccccctgctcaagctcttgcaggaggctcagcaaagctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
3D Structure (11)   
   PDB (11)   
Protein domain (2)   
   Pfam (2)   
All databases (73)   

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