KEGG   Homo sapiens (human): 2934
Entry
2934              CDS       T01001                                 
Symbol
GSN, ADF, AGEL
Name
(RefSeq) gelsolin
  KO
K05768  gelsolin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05203  Viral carcinogenesis
Disease
H02322  Amyloidosis, Finnish type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    2934 (GSN)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    2934 (GSN)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    2934 (GSN)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    2934 (GSN)
   04147 Exosome [BR:hsa04147]
    2934 (GSN)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Gelsolin / villin
     2934 (GSN)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   2934 (GSN)
SSDB
Motif
Pfam: Gelsolin
Other DBs
NCBI-GeneID: 2934
NCBI-ProteinID: NP_000168
OMIM: 137350
HGNC: 4620
Ensembl: ENSG00000148180
UniProt: P06396 A0A384MEF1
Structure
Position
9:121201483..121332842
AA seq 782 aa
MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFL
KAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNEC
SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVV
PNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA
TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKL
YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK
TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERV
PFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY
RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFG
GKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPS
AAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDK
KMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEK
TEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAEL
AA
NT seq 2349 nt   +upstreamnt  +downstreamnt
atggctccgcaccgccccgcgcccgcgctgctttgcgcgctgtccctggcgctgtgcgcg
ctgtcgctgcccgtccgcgcggccactgcgtcgcggggggcgtcccaggcgggggcgccc
caggggcgggtgcccgaggcgcggcccaacagcatggtggtggaacaccccgagttcctc
aaggcagggaaggagcctggcctgcagatctggcgtgtggagaagttcgatctggtgccc
gtgcccaccaacctttatggagacttcttcacgggcgacgcctacgtcatcctgaagaca
gtgcagctgaggaacggaaatctgcagtatgacctccactactggctgggcaatgagtgc
agccaggatgagagcggggcggccgccatctttaccgtgcagctggatgactacctgaac
ggccgggccgtgcagcaccgtgaggtccagggcttcgagtcggccaccttcctaggctac
ttcaagtctggcctgaagtacaagaaaggaggtgtggcatcaggattcaagcacgtggta
cccaacgaggtggtggtgcagagactcttccaggtcaaagggcggcgtgtggtccgtgcc
accgaggtacctgtgtcctgggagagcttcaacaatggcgactgcttcatcctggacctg
ggcaacaacatccaccagtggtgtggttccaacagcaatcggtatgaaagactgaaggcc
acacaggtgtccaagggcatccgggacaacgagcggagtggccgggcccgagtgcacgtg
tctgaggagggcactgagcccgaggcgatgctccaggtgctgggccccaagccggctctg
cctgcaggtaccgaggacaccgccaaggaggatgcggccaaccgcaagctggccaagctc
tacaaggtctccaatggtgcagggaccatgtccgtctccctcgtggctgatgagaacccc
ttcgcccagggggccctgaagtcagaggactgcttcatcctggaccacggcaaagatggg
aaaatctttgtctggaaaggcaagcaggcaaacacggaggagaggaaggctgccctcaaa
acagcctctgacttcatcaccaagatggactaccccaagcagactcaggtctcggtcctt
cctgagggcggtgagaccccactgttcaagcagttcttcaagaactggcgggacccagac
cagacagatggcctgggcttgtcctacctttccagccatatcgccaacgtggagcgggtg
cccttcgacgccgccaccctgcacacctccactgccatggccgcccagcacggcatggat
gacgatggcacaggccagaaacagatctggagaatcgaaggttccaacaaggtgcccgtg
gaccctgccacatatggacagttctatggaggcgacagctacatcattctgtacaactac
cgccatggtggccgccaggggcagataatctataactggcagggtgcccagtctacccag
gatgaggtcgctgcatctgccatcctgactgctcagctggatgaggagctgggaggtacc
cctgtccagagccgtgtggtccaaggcaaggagcccgcccacctcatgagcctgtttggt
gggaagcccatgatcatctacaagggcggcacctcccgcgagggcgggcagacagcccct
gccagcacccgcctcttccaggtccgcgccaacagcgctggagccacccgggctgttgag
gtattgcctaaggctggtgcactgaactccaacgatgcctttgttctgaaaaccccctca
gccgcctacctgtgggtgggtacaggagccagcgaggcagagaagacgggggcccaggag
ctgctcagggtgctgcgggcccaacctgtgcaggtggcagaaggcagcgagccagatggc
ttctgggaggccctgggcgggaaggctgcctaccgcacatccccacggctgaaggacaag
aagatggatgcccatcctcctcgcctctttgcctgctccaacaagattggacgttttgtg
atcgaagaggttcctggtgagctcatgcaggaagacctggcaacggatgacgtcatgctt
ctggacacctgggaccaggtctttgtctgggttggaaaggattctcaagaagaagaaaag
acagaagccttgacttctgctaagcggtacatcgagacggacccagccaatcgggatcgg
cggacgcccatcaccgtggtgaagcaaggctttgagcctccctcctttgtgggctggttc
cttggctgggatgatgattactggtctgtggaccccttggacagggccatggctgagctg
gctgcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PROTHERM (4)   
Protein sequence (61)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (58)   
DNA sequence (118)   
   RefSeq(nuc) (58)   
   GenBank (30)   
   EMBL (30)   
3D Structure (58)   
   PDB (58)   
Protein domain (1)   
   Pfam (1)   
All databases (269)   

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