KEGG   Homo sapiens (human): 29761
Entry
29761             CDS       T01001                                 
Symbol
USP25, USP21
Name
(RefSeq) ubiquitin specific peptidase 25
  KO
K11849  ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04657  IL-17 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    29761 (USP25)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    29761 (USP25)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    29761 (USP25)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     29761 (USP25)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   29761 (USP25)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    29761 (USP25)
SSDB
Motif
Pfam: UCH UIM UBA_4
Other DBs
NCBI-GeneID: 29761
NCBI-ProteinID: NP_037528
OMIM: 604736
HGNC: 12624
Ensembl: ENSG00000155313
UniProt: Q9UHP3
Structure
Position
21:15729982..15880064
AA seq 1055 aa
MTVEQNVLQQSAAQKHQQTFLNQLREITGINDTQILQQALKDSNGNLELAVAFLTAKNAK
TPQQEETTYYQTALPGNDRYISVGSQADTNVIDLTGDDKDDLQRAIALSLAESNRAFRET
GITDEEQAISRVLEASIAENKACLKRTPTEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWF
SAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYV
DPSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFY
GRFLAVGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSENSGKSGQE
HWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEIK
RLKDYLTVLQQRLERYLSYGSGPKRFPLVDVLQYALEFASSKPVCTSPVDDIDASSPPSG
SIPSQTLPSTTEQQGALSSELPSTSPSSVAAISSRSVIHKPFTQSRIPPDLPMHPAPRHI
TEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHE
GQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASAYCLMYINDKAQ
FLIQEEFNKETGQPLVGIETLPPDLRDFVEEDNQRFEKELEEWDAQLAQKALQEKLLASQ
KLRESETSVTTAQAAGDPEYLEQPSRSDFSKHLKEETIQIITKASHEHEDKSPETVLQSA
IKLEYARLVKLAQEDTPPETDYRLHHVVVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERC
HNIMKVAQAKLEMIKPEEVNLEEYEEWHQDYRKFRETTMYLIIGLENFQRESYIDSLLFL
ICAYQNNKELLSKGLYRGHDEELISHYRRECLLKLNEQAAELFESGEDREVNNGLIIMNE
FIVPFLPLLLVDEMEEKDILAVEDMRNRWCSYLGQEMEPHLQEKLTDFLPKLLDCSMEIK
SFHEPPKLPSYSTHELCERFARIMLSLSRTPADGR
NT seq 3168 nt   +upstreamnt  +downstreamnt
atgaccgtggagcagaacgtgctgcagcagagcgcggcgcagaagcaccagcagacgttt
ttgaatcaactgagagaaattacggggattaatgacacccagatactacagcaagccttg
aaggatagtaatggaaacttggaattagcagtggctttccttactgcgaagaatgctaag
acccctcagcaggaggagacaacttactaccaaacagcacttcctggcaatgatagatac
atcagtgtgggaagccaagcagatacaaatgtgattgatctcactggagatgataaagat
gatcttcagagagcaattgccttgagtttggccgaatcaaacagggcattcagggagact
ggaataactgatgaggaacaagccattagcagagttcttgaagccagcatagcagagaat
aaagcatgtttgaagaggacacctacagaagtttggagggattctcgaaacccttatgat
agaaaaagacaggacaaagctcccgttgggctaaagaatgttggcaatacttgttggttt
agtgctgttattcagtcattatttaatcttttggaatttagaagattagttctgaattac
aagcctccatcaaatgctcaagatttaccccgaaaccaaaaggaacatcggaatttgcct
tttatgcgtgagctgaggtatctatttgcacttcttgttggtaccaaaaggaagtatgtt
gatccatcaagagcagttgaaattcttaaggatgctttcaaatcaaatgactcacagcag
caagatgtgagtgagtttacacacaaattattagattggttagaagatgccttccaaatg
aaagctgaagaggagacggatgaagagaagccaaagaaccccatggtagagttgttctat
ggcagattcctggctgtgggagtacttgaaggtaaaaaatttgaaaacactgaaatgttt
ggtcagtacccacttcaggtcaatgggttcaaagatctgcatgagtgcctagaagctgca
atgattgaaggagaaattgagtctttacattcagagaattcaggaaaatcaggccaagag
cattggtttactgaattaccacctgtgttaacatttgaattgtcaagatttgaatttaat
caggcattgggaagaccagaaaaaattcacaacaaattagaatttccccaagttttatat
ttggacagatacatgcacagaaacagagaaataacaagaattaagagggaagagatcaag
agactgaaagattacctcacggtattacaacaaaggctagaaagatatttaagctatggt
tccggtcccaaacgattccccttggtagatgttcttcagtatgcattggaatttgcctca
agtaaacctgtttgcacttctcctgttgacgatattgacgctagttccccacctagtggt
tccataccatcacagacattaccaagcacaacagaacaacagggagccctatcttcagaa
ctgccaagcacatcaccttcatcagttgctgccatttcatcgagatcagtaatacacaaa
ccatttactcagtcccggatacctccagatttgcccatgcatccggcaccaaggcacata
acggaggaagaactttctgtgctggaaagttgtttacatcgctggaggacagaaatagaa
aatgacaccagagatttgcaggaaagcatatccagaatccatcgaacaattgaattaatg
tactctgacaaatctatgatacaagttccttatcgattacatgccgttttagttcacgaa
ggccaagctaatgctgggcactactgggcatatatttttgatcatcgtgaaagcagatgg
atgaagtacaatgatattgctgtgacaaaatcatcatgggaagagctagtgagggactct
tttggtggttatagaaatgccagtgcatactgtttaatgtacataaatgataaggcacag
ttcctaatacaagaggagtttaataaagaaactgggcagccccttgttggtatagaaaca
ttaccaccggatttgagagattttgttgaggaagacaaccaacgatttgaaaaagaacta
gaagaatgggatgcacaacttgcccagaaagctttgcaggaaaagcttttagcgtctcag
aaattgagagagtcagagacttctgtgacaacagcacaagcagcaggagacccagaatat
ctagagcagccatcaagaagtgatttctcaaagcacttgaaagaagaaactattcaaata
attaccaaggcatcacatgagcatgaagataaaagtcctgaaacagttttgcagtcggca
attaagttggaatatgcaaggttggttaagttggcccaagaagacaccccaccagaaacc
gattatcgtttacatcatgtagtggtctactttatccagaaccaggcaccaaagaaaatt
attgagaaaacattactagaacaatttggagatagaaatttgagttttgatgaaaggtgt
cacaacataatgaaagttgctcaagccaaactggaaatgataaaacctgaagaagtaaac
ttggaggaatatgaggagtggcatcaggattataggaaattcagggaaacaactatgtat
ctcataattgggctagaaaattttcaaagagaaagttatatagattccttgctgttcctc
atctgtgcttatcagaataacaaagaactcttgtctaaaggcttatacagaggacatgat
gaagaattgatatcacattatagaagagaatgtttgctaaaattaaatgagcaagccgca
gaactcttcgaatctggagaggatcgagaagtaaacaatggtttgattatcatgaatgag
tttattgtcccatttttgccattattactggtggatgaaatggaagaaaaggatatacta
gctgtagaagatatgagaaatcgatggtgttcctaccttggtcaagaaatggaaccacac
ctccaagaaaagctgacagattttttgccaaaactgcttgattgttctatggagattaaa
agtttccatgagccaccgaagttaccttcatattccacgcatgaactctgtgagcgattt
gcccgaatcatgttgtccctcagtcgaactcctgctgatggaagataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (32)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (30)   
DNA sequence (56)   
   RefSeq(nuc) (30)   
   GenBank (13)   
   EMBL (13)   
3D Structure (7)   
   PDB (7)   
Protein domain (3)   
   Pfam (3)   
All databases (122)   

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