KEGG   Homo sapiens (human): 2986
Entry
2986              CDS       T01001                                 
Symbol
GUCY2F, CYGF, GC-F, GUC2DL, GUC2F, RETGC-2, ROS-GC2
Name
(RefSeq) guanylate cyclase 2F, retinal
  KO
K12322  guanylate cyclase 2F [EC:4.6.1.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
hsa04744  Phototransduction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    2986 (GUCY2F)
 09150 Organismal Systems
  09157 Sensory system
   04744 Phototransduction
    2986 (GUCY2F)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2986 (GUCY2F)
Enzymes [BR:hsa01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.2  guanylate cyclase
     2986 (GUCY2F)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  RGC family [OT]
   2986 (GUCY2F)
SSDB
Motif
Pfam: ANF_receptor Guanylate_cyc PK_Tyr_Ser-Thr Pkinase HNOBA JHBP Kinase-like TetR_C_11
Other DBs
NCBI-GeneID: 2986
NCBI-ProteinID: NP_001513
OMIM: 300041
HGNC: 4691
Ensembl: ENSG00000101890
UniProt: P51841
Position
X:complement(109372906..109482086)
AA seq 1108 aa
MFLGLGRFSRLVLWFAAFRKLLGHHGLASAKFLWCLCLLSVMSLPQQVWTLPYKIGVVGP
WACDSLFSKALPEVAARLAIERINRDPSFDLSYSFEYVILNEDCQTSRALSSFISHHQMA
SGFIGPTNPGYCEAASLLGNSWDKGIFSWACVNYELDNKISYPTFSRTLPSPIRVLVTVM
KYFQWAHAGVISSDEDIWVHTANRVASALRSHGLPVGVVLTTGQDSQSMRKALQRIHQAD
RIRIIIMCMHSALIGGETQMHLLECAHDLKMTDGTYVFVPYDALLYSLPYKHTPYRVLRN
NPKLREAYDAVLTITVESQEKTFYQAFTEAAARGEIPEKLEFDQVSPLFGTIYNSIYFIA
QAMNNAMKENGQAGAASLVQHSRNMQFHGFNQLMRTDSNGNGISEYVILDTNLKEWELHS
TYTVDMEMELLRFGGTPIHFPGGRPPRADAKCWFAEGKICHGGIDPAFAMMVCLTLLIAL
LSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFINPHFGSKRGSRASVSFQITSEVQS
GRSPRLSFSSGSLTPATYENSNIAIYEGDWVWLKKFSLGDFGDLKSIKSRASDVFEMMKD
LRHENINPLLGFFYDSGMFAIVTEFCSRGSLEDILTNQDVKLDWMFKSSLLLDLIKGMKY
LHHREFVHGRLKSRNCVVDGRFVLKVTDYGFNDILEMLRLSEEESSMEELLWTAPELLRA
PRGSRLGSFAGDVYSFAIIMQEVMVRGTPFCMMDLPAQEIINRLKKPPPVYRPVVPPEHA
PPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIR
ERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMS
EPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDI
LSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPY
RIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWLIGKKGFMKPLPVPPPVDKDG
QVGHGLQPVEIAAFQRRKAERQLVRNKP
NT seq 3327 nt   +upstreamnt  +downstreamnt
atgttcctgggactcgggcgcttttctcgccttgttctctggtttgcggctttcaggaaa
ctgctgggacaccatggccttgcatctgccaagttcctgtggtgcttgtgccttctgtct
gtcatgtcccttccgcagcaggtgtggacactcccctacaagataggggtggtgggccct
tgggcttgtgattcgctgttttcaaaggccctgcctgaggttgctgcgcgattagccatt
gagcgaatcaaccgggacccatcttttgacctgagttattcttttgaatacgtgattctc
aatgaagactgccagacttcgagggctctctccagtttcatttcccaccaccagatggcc
tcaggatttattggacctaccaaccctggctactgcgaggcagcctcgctcctgggaaac
agctgggacaaaggaattttctcttgggcttgtgtgaattatgaattagacaataaaatt
agctacccgaccttttctcggacactcccttctcccatccgggtgcttgtaactgtcatg
aaatatttccagtgggctcatgctggagtcatttcctcagatgaagacatttgggtgcat
acagccaatcgagtcgcaagtgctcttcggagccacggcttacctgtaggggtcgtcctg
accacaggacaagacagccaaagcatgcggaaagccctccagaggattcaccaggcagac
agaattcgcataatcatcatgtgtatgcattcagctttgattgggggagagactcagatg
catctcttggaatgtgctcatgatctgaaaatgactgatggaacctacgtctttgttcct
tatgatgccctgctctacagtttaccttataagcacaccccctaccgggtcctaaggaac
aacccaaagctccgggaagcctatgatgcagtgttgaccattacagtggagtcccaagaa
aagaccttctatcaagccttcacagaggcagcagcaagaggtgaaattcctgagaagctg
gagttcgatcaagtttcaccgttgtttggaaccatctacaattcaatttactttatcgca
caagccatgaataatgctatgaaagaaaatggacaggctggtgctgccagcctggttcag
cattccagaaacatgcagttccatggattcaaccagttgatgaggacagattcaaatgga
aatggaatttcagaatatgtaatcctggacaccaacttgaaagaatgggaactccatagc
acctacactgtggacatggaaatggagctgctacgtttcggagggacccctattcacttc
cctggtggcaggccccctagagcagatgcaaaatgctggtttgcagaagggaagatctgc
catggaggcatcgaccctgcctttgccatgatggtctgccttactttgcttatagccctg
ctgtctattaatggatttgcttactttataaggcgtcgtataaataaaatccagttgatc
aaaggacccaatagaattctactgactttggaggatgtaacgtttatcaatccccacttt
ggcagtaagagaggaagtcgtgccagtgtaagcttccagattacctcagaggtccaaagt
gggaggtccccaagactctccttttcttcagggagtctaactccagctacctatgaaaac
tccaacatagcgatttatgagggtgattgggtgtggctgaaaaagttctcccttggagat
tttggagaccttaagtccatcaaatcaagagcaagtgatgtgttcgaaatgatgaaggac
ttgcgtcatgagaatattaaccctttattgggtttcttctatgattcggggatgtttgcc
attgtgacagaattctgttcccgagggagcctagaagacatactgacaaatcaagatgtg
aaacttgactggatgtttaaatcatcactcttgctggatctcataaagggcatgaagtac
ttacaccacagagagtttgttcatgggaggctaaagtctcgaaactgtgtggtagatggg
cgttttgtactaaaagtgacagattatggctttaacgacatcttagaaatgctgagactc
tctgaagaggaatcttctatggaagagctgctgtggacggcccctgaactgttgagagct
ccaagaggcagcaggttaggttcttttgcaggagatgtctatagctttgccatcatcatg
caagaagtgatggtccggggtaccccattctgcatgatggatctgccagctcaagaaatc
ataaacagacttaagaagcctcctcctgtgtacagaccagtagttcctcctgagcatgcc
cctccagaatgtctccagctgatgaagcagtgctgggctgaggctgcagaacaacgacca
acttttgatgaaatatttaaccagtttaaaacttttaataaagggaagaagaccaatatt
attgattctatgcttcggatgttggagcaatattctagcaacttggaagatttgattcgg
gagcggactgaagagctggaaattgaaaaacagaaaacggaaaagcttctaacacagatg
ctaccaccatcagttgctgaatctctcaaaaagggctgcacagttgaacctgagggcttt
gacttggtcaccttgtacttcagcgacattgtgggcttcacaaccatttcagccatgagt
gagcccattgaggtcgtggatcttctgaatgacctgtacacactctttgatgcaataatt
ggcagtcatgatgtctacaaggtagagaccattggagatgcctacatggtggcttcaggc
ctcccaaagaggaatggcagtaggcatgcagctgagattgcaaacatgtccttagatatc
ctgagctctgtgggcactttcaagatgcggcacatgccagaagtgccggtccgaattcga
attggccttcactcagggccggttgttgctggagtggtgggcctcaccatgcccagatac
tgcttgtttggagacactgtgaacacagcttctcggatggaatctacaggcttaccttat
cgcattcatgtcagtctcagcactgttacaattcttcaaaatctgagtgagggctatgaa
gtggagcttcgaggaagaacagagctcaagggcaaaggcacagaggaaaccttctggctg
attgggaaaaaaggcttcatgaagccccttcctgtgcccccaccagtggacaaagatggg
caagtgggccatggcctgcaaccagtggagattgcagccttccaaagaagaaaagcagaa
aggcagttggtgagaaacaagccataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (8)   
   Pfam (8)   
All databases (38)   

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