KEGG   Homo sapiens (human): 2987
Entry
2987              CDS       T01001                                 
Symbol
GUK1, GMK
Name
(RefSeq) guanylate kinase 1
  KO
K00942  guanylate kinase [EC:2.7.4.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
Module
hsa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    2987 (GUK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.8  guanylate kinase
     2987 (GUK1)
SSDB
Motif
Pfam: Guanylate_kin AAA_18 AAA_33 AAA_16 AAA_22 MMR_HSR1 RsgA_GTPase ABC_tran NACHT cobW AAA_28 AAA_24 AAA_14 AAA_30 AAA_29 dNK ATPase_2 NTPase_1 AAA_17 nSTAND3 AAA_5 RNA_helicase Radical_SAM_2 Rad17 Viral_helicase1 YobI-ATPase AAA Methyltransf_12 Dynamin_N AAA_7 Roc
Other DBs
NCBI-GeneID: 2987
NCBI-ProteinID: NP_000849
OMIM: 139270
HGNC: 4693
Ensembl: ENSG00000143774
UniProt: Q16774 Q6IBG8
Structure
Position
1:228140084..228148955
AA seq 197 aa
MSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREV
MQRDIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYI
SVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAE
LKEALSEEIKKAQRTGA
NT seq 594 nt   +upstreamnt  +downstreamnt
atgtcgggccccaggcctgtggtgctgagcgggccttcgggagctgggaagagcaccctg
ctgaagaggctgctccaggagcacagcggcatctttggcttcagcgtgtcccataccacg
aggaacccgaggcccggcgaggagaacggcaaagattactactttgtaaccagggaggtg
atgcagcgtgacatagcagccggcgacttcatcgagcatgccgagttctcggggaacctg
tatggcacgagcaaggtggcggtgcaggccgtgcaggccatgaaccgcatctgtgtgctg
gacgtggacctgcagggtgtgcggaacatcaaggccaccgatctgcggcccatctacatc
tctgtgcagccgccttcactgcacgtgctggagcagcggctgcggcagcgcaacactgaa
accgaggagagcctggtgaagcggctggctgctgcccaggccgacatggagagcagcaag
gagcccggcctgtttgatgtggtcatcattaacgacagcctggaccaggcctacgcagag
ctgaaggaggcgctctctgaggaaatcaagaaagctcaaaggaccggcgcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (29)   
   OC (1)   
Protein sequence (25)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (22)   
DNA sequence (64)   
   RefSeq(nuc) (22)   
   GenBank (21)   
   EMBL (21)   
3D Structure (1)   
   PDB (1)   
Protein domain (31)   
   Pfam (31)   
All databases (183)   

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