KEGG   Homo sapiens (human): 30833
Entry
30833             CDS       T01001                                 
Symbol
NT5C, DNT, DNT1, HEL74, P5N2, PN-I, PN-II, UMPH2, cdN, dNT-1
Name
(RefSeq) 5', 3'-nucleotidase, cytosolic
  KO
K01081  5'-nucleotidase [EC:3.1.3.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00240  Pyrimidine metabolism
hsa00760  Nicotinate and nicotinamide metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
Module
hsa_M00958  Adenine ribonucleotide degradation, AMP => Urate
hsa_M00959  Guanine ribonucleotide degradation, GMP => Urate
Network
nt06027  Purine salvage pathway
  Element
N01418  Purine salvage pathway, adenine to AMP
N01421  Purine salvage pathway, hypoxanthine/guanine to IMP/GMP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    30833 (NT5C)
   00240 Pyrimidine metabolism
    30833 (NT5C)
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    30833 (NT5C)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.5  5'-nucleotidase
     30833 (NT5C)
SSDB
Motif
Pfam: NT5C Hydrolase
Other DBs
NCBI-GeneID: 30833
NCBI-ProteinID: NP_055410
OMIM: 191720
HGNC: 17144
Ensembl: ENSG00000125458
UniProt: Q8TCD5 V9HWF3
Structure
Position
17:complement(75130228..75131742)
AA seq 201 aa
MARSVRVLVDMDGVLADFEAGLLRGFRRRFPEEPHVPLEQRRGFLAREQYRALRPDLADK
VASVYEAPGFFLDLEPIPGALDAVREMNDLPDTQVFICTSPLLKYHHCVGEKYRWVEQHL
GPQFVERIILTRDKTVVLGDLLIDDKDTVRGQEETPSWEHILFTCCHNRHLVLPPTRRRL
LSWSDNWREILDSKRGAAQRE
NT seq 606 nt   +upstreamnt  +downstreamnt
atggcgcggagcgtgcgcgtgctggtggacatggacggcgtcctggccgacttcgaggcc
ggcctcctgcggggcttccgccgccgcttccctgaggagccgcacgtgccgctggagcaa
cgccgcggcttcctggcccgcgagcagtaccgcgccctgcggcccgacctggcggataaa
gtggccagtgtgtacgaagccccgggctttttcctggacctggagcccatcccgggagcc
ttggacgctgtgcgggagatgaacgacctaccggacacgcaggtcttcatctgcaccagc
cccctgctgaagtaccaccactgtgtgggtgagaagtaccgctgggtggagcagcacctg
gggccccagttcgtagaacgaattatcctgacaagggacaagacggtggtcttgggggac
ctgctcattgatgacaaggacacagttcgaggccaggaggagaccccaagctgggagcac
atcttgttcacctgctgccacaatcggcacctggtcctgcccccgacaaggagacggctg
ctctcctggagtgacaactggagggagatcttagatagcaagcgcggagctgcgcagcgg
gaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (30)   
   KEGG COMPOUND (30)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (120)   

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