Entry |
|
Symbol |
HLA-DMA, D6S222E, DMA, HLADM, RING6
|
Name |
(RefSeq) major histocompatibility complex, class II, DM alpha
|
KO |
|
Organism |
|
Pathway |
hsa04612 | Antigen processing and presentation |
hsa04658 | Th1 and Th2 cell differentiation |
hsa04672 | Intestinal immune network for IgA production |
hsa05150 | Staphylococcus aureus infection |
hsa05166 | Human T-cell leukemia virus 1 infection |
hsa05168 | Herpes simplex virus 1 infection |
|
Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06168 Herpes simplex virus 1 (HSV-1) |
Element |
N00508 | HTLV-1 Tax to NFY-mediated transcription |
N00590 | Antigen processing and presentation by MHC class II molecules |
|
Disease |
|
Drug target |
Glatiramer acetate: | D04318<JP/US> |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
3108 (HLA-DMA)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
3108 (HLA-DMA)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
3108 (HLA-DMA)
04612 Antigen processing and presentation
3108 (HLA-DMA)
04658 Th1 and Th2 cell differentiation
3108 (HLA-DMA)
04659 Th17 cell differentiation
3108 (HLA-DMA)
04672 Intestinal immune network for IgA production
3108 (HLA-DMA)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
3108 (HLA-DMA)
05164 Influenza A
3108 (HLA-DMA)
05168 Herpes simplex virus 1 infection
3108 (HLA-DMA)
05169 Epstein-Barr virus infection
3108 (HLA-DMA)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
3108 (HLA-DMA)
05152 Tuberculosis
3108 (HLA-DMA)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3108 (HLA-DMA)
05140 Leishmaniasis
3108 (HLA-DMA)
09163 Immune disease
05310 Asthma
3108 (HLA-DMA)
05322 Systemic lupus erythematosus
3108 (HLA-DMA)
05323 Rheumatoid arthritis
3108 (HLA-DMA)
05320 Autoimmune thyroid disease
3108 (HLA-DMA)
05321 Inflammatory bowel disease
3108 (HLA-DMA)
05330 Allograft rejection
3108 (HLA-DMA)
05332 Graft-versus-host disease
3108 (HLA-DMA)
09166 Cardiovascular disease
05416 Viral myocarditis
3108 (HLA-DMA)
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
3108 (HLA-DMA)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
3108 (HLA-DMA)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
3108 (HLA-DMA)
Exosomal proteins of epithelial cells
3108 (HLA-DMA)
Exosomal proteins of breast milk
3108 (HLA-DMA)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
|
Position |
6:complement(32948618..32953097)
|
AA seq |
261 aa
MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLS
EAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKI
PVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVD
GLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLG
VLGIIVGIVLIIYFRKPCSGD |
NT seq |
786 nt +upstreamnt +downstreamnt
atgggtcatgaacagaaccaaggagctgcgctgctacagatgttaccacttctgtggctg
ctaccccactcctgggccgtccctgaagctcctactccaatgtggccagatgacctgcaa
aaccacacattcctgcacacagtgtactgccaggatgggagtcccagtgtgggactctct
gaggcctacgacgaggaccagcttttcttcttcgacttttcccagaacactcgggtgcct
cgcctgcccgaatttgctgactgggctcaggaacagggagatgctcctgccattttattt
gacaaagagttctgcgagtggatgatccagcaaatagggccaaaacttgatgggaaaatc
ccggtgtccagagggtttcctatcgctgaagtgttcacgctgaagcccctggagtttggc
aagcccaacactttggtctgttttgtcagtaatctcttcccacccatgctgacagtgaac
tggcagcatcattccgtccctgtggaaggatttgggcctacttttgtctcagctgtcgat
ggactcagcttccaggccttttcttacttaaacttcacaccagaaccttctgacattttc
tcctgcattgtgactcacgaaattgaccgctacacagcaattgcctattgggtaccccgg
aacgcactgccctcagatctgctggagaatgtgctgtgtggcgtggcctttggcctgggt
gtgctgggcatcatcgtgggcattgttctcatcatctacttccggaagccttgctcaggt
gactga |