Entry |
|
Symbol |
HLA-DQA1, CELIAC1, DQ-A1, DQA1, HLA-DQA, HLA-DQA1*, HLA-DQB1
|
Name |
(RefSeq) major histocompatibility complex, class II, DQ alpha 1
|
KO |
|
Organism |
|
Pathway |
hsa04612 | Antigen processing and presentation |
hsa04658 | Th1 and Th2 cell differentiation |
hsa04672 | Intestinal immune network for IgA production |
hsa05150 | Staphylococcus aureus infection |
hsa05166 | Human T-cell leukemia virus 1 infection |
hsa05168 | Herpes simplex virus 1 infection |
|
Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06168 Herpes simplex virus 1 (HSV-1) |
Element |
N00508 | HTLV-1 Tax to NFY-mediated transcription |
N00590 | Antigen processing and presentation by MHC class II molecules |
|
Disease |
H00080 | Systemic lupus erythematosus |
H00408 | Type 1 diabetes mellitus |
H01362 | Dermatitis herpetiformis |
|
Drug target |
Glatiramer acetate: | D04318<JP/US> |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
3117 (HLA-DQA1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
3117 (HLA-DQA1)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
3117 (HLA-DQA1)
04612 Antigen processing and presentation
3117 (HLA-DQA1)
04658 Th1 and Th2 cell differentiation
3117 (HLA-DQA1)
04659 Th17 cell differentiation
3117 (HLA-DQA1)
04672 Intestinal immune network for IgA production
3117 (HLA-DQA1)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
3117 (HLA-DQA1)
05164 Influenza A
3117 (HLA-DQA1)
05168 Herpes simplex virus 1 infection
3117 (HLA-DQA1)
05169 Epstein-Barr virus infection
3117 (HLA-DQA1)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
3117 (HLA-DQA1)
05152 Tuberculosis
3117 (HLA-DQA1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3117 (HLA-DQA1)
05140 Leishmaniasis
3117 (HLA-DQA1)
09163 Immune disease
05310 Asthma
3117 (HLA-DQA1)
05322 Systemic lupus erythematosus
3117 (HLA-DQA1)
05323 Rheumatoid arthritis
3117 (HLA-DQA1)
05320 Autoimmune thyroid disease
3117 (HLA-DQA1)
05321 Inflammatory bowel disease
3117 (HLA-DQA1)
05330 Allograft rejection
3117 (HLA-DQA1)
05332 Graft-versus-host disease
3117 (HLA-DQA1)
09166 Cardiovascular disease
05416 Viral myocarditis
3117 (HLA-DQA1)
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
3117 (HLA-DQA1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
3117 (HLA-DQA1)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
3117 (HLA-DQA1)
Exosomal proteins of epithelial cells
3117 (HLA-DQA1)
Exosomal proteins of breast milk
3117 (HLA-DQA1)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
|
Position |
6:32637406..32655272
|
AA seq |
255 aa
MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYV
DLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSK
SPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFL
PSADEIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFII
QGLRSVGASRHQGPL |
NT seq |
768 nt +upstreamnt +downstreamnt
atgatcctaaacaaagctctgctgctgggggccctcgctctgaccaccgtgatgagcccc
tgtggaggtgaagacattgtggctgaccacgttgcctcttgtggtgtaaacttgtaccag
ttttacggtccctctggccagtacacccatgaatttgatggagatgagcagttctacgtg
gacctggagaggaaggagactgcctggcggtggcctgagttcagcaaatttggaggtttt
gacccgcagggtgcactgagaaacatggctgtggcaaaacacaacttgaacatcatgatt
aaacgctacaactctaccgctgctaccaatgaggttcctgaggtcacagtgttttccaag
tctcccgtgacactgggtcagcccaacaccctcatttgtcttgtggacaacatctttcct
cctgtggtcaacatcacatggctgagcaatgggcagtcagtcacagaaggtgtttctgag
accagcttcctctccaagagtgatcattccttcttcaagatcagttacctcaccttcctc
ccttctgctgatgagatttatgactgcaaggtggagcactggggcctggaccagcctctt
ctgaaacactgggagcctgagattccagcccctatgtcagagctcacagagactgtggtc
tgtgccctggggttgtctgtgggcctcatgggcattgtggtgggcactgtcttcatcatc
caaggcctgcgttcagttggtgcttccagacaccaagggccattgtga |