KEGG   Homo sapiens (human): 3419
Entry
3419              CDS       T01001                                 
Symbol
IDH3A, RP90
Name
(RefSeq) isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
  KO
K00030  isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00020  Citrate cycle (TCA cycle)
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Module
hsa_M00009  Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Network
nt06031  Citrate cycle and pyruvate metabolism
  Element
N01604  Citrate cycle, first carbon oxidation
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    3419 (IDH3A)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.41  isocitrate dehydrogenase (NAD+)
     3419 (IDH3A)
SSDB
Motif
Pfam: Iso_dh
Other DBs
NCBI-GeneID: 3419
NCBI-ProteinID: NP_005521
OMIM: 601149
HGNC: 5384
Ensembl: ENSG00000166411
UniProt: P50213
Structure
Position
15:78149362..78171945
AA seq 366 aa
MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
RVKDLD
NT seq 1101 nt   +upstreamnt  +downstreamnt
atggctgggcccgcgtggatctctaaggtctctcggctgctgggggcattccacaaccca
aaacaggtgaccagaggttttactggtggtgttcagacagtaactttaattccaggagat
ggtattggcccagaaatttcagctgcagttatgaagatttttgatgctgccaaagcacct
attcagtgggaggagcggaacgtcactgccattcaaggacctggaggaaagtggatgatc
ccttcagaggctaaagagtccatggataagaacaagatgggcttgaaaggccctttgaag
accccaatagcagccggtcacccatctatgaatttactgctgcgcaaaacatttgacctt
tacgcgaatgtccgaccatgtgtctctatcgaaggctataaaaccccttacaccgatgta
aatattgtgaccattcgagagaacacagaaggagaatacagtggaattgagcatgtgatt
gttgatggagtcgtgcagagtatcaagctcatcaccgagggggcgagcaagcgcattgct
gagtttgcctttgagtatgcccggaacaaccaccggagcaacgtcacggcggtgcacaaa
gccaacatcatgcggatgtcagatgggctttttctacaaaaatgcagggaagttgcagaa
agctgtaaagatattaaatttaatgagatgtaccttgatacagtatgtttgaatatggta
caagatccttcccaatttgatgttcttgttatgccaaatttgtatggagacatccttagt
gacttgtgtgcaggattgatcggaggtctcggtgtgacaccaagtggcaacattggagcc
aatggggttgcaatttttgagtcggttcatgggacggctccagacattgcaggcaaggac
atggcgaatcccacagccctcctgctcagtgccgtgatgatgctgcgccacatgggactt
tttgaccatgctgcaagaattgaggctgcgtgttttgctacaattaaggacggaaagagc
ttgacaaaagatttgggaggcaatgcaaaatgctcagacttcacagaggaaatctgtcgc
cgagtaaaagatttagattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (34)   
   RefSeq(nuc) (8)   
   GenBank (13)   
   EMBL (13)   
3D Structure (19)   
   PDB (19)   
Protein domain (1)   
   Pfam (1)   
All databases (96)   

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