KEGG   Homo sapiens (human): 3420
Entry
3420              CDS       T01001                                 
Symbol
IDH3B, RP46
Name
(RefSeq) isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
  KO
K00030  isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00020  Citrate cycle (TCA cycle)
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Module
hsa_M00009  Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Network
nt06031  Citrate cycle and pyruvate metabolism
  Element
N01604  Citrate cycle, first carbon oxidation
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    3420 (IDH3B)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.41  isocitrate dehydrogenase (NAD+)
     3420 (IDH3B)
SSDB
Motif
Pfam: Iso_dh AAA_3
Other DBs
NCBI-GeneID: 3420
NCBI-ProteinID: NP_008830
OMIM: 604526
HGNC: 5385
Ensembl: ENSG00000101365
UniProt: O43837
Structure
Position
20:complement(2658395..2664216)
AA seq 385 aa
MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
RDMGGYSTTTDFIKSVIGHLQTKGS
NT seq 1158 nt   +upstreamnt  +downstreamnt
atggcggcattgagcggagtccgctggctgacccgagcgctggtctccgccgggaaccct
ggggcatggagaggtctgagtacctcggccgcggcgcacgctgcatcgcggagccaggcc
gaggacgtgagggtggagggctcctttcccgtgaccatgcttccgggagacggtgtgggg
cctgagctgatgcacgccgtcaaggaggtgttcaaggctgccgctgtcccagtggagttc
caggagcaccacctgagtgaggtgcagaatatggcatctgaggagaagctggagcaggtg
ctgagttccatgaaggagaacaaagtggccatcattggaaagattcataccccgatggag
tataagggggagctagcctcctatgatatgcggctgaggcgtaagttggacttatttgcc
aacgtagtccatgtgaagtcacttcctgggtatatgactcggcacaacaatctagacctg
gtgatcattcgagagcagacagaaggggagtacagctctctggaacatgagagtgcaagg
ggtgtgattgagtgtttgaagattgtcacacgagccaagtctcagcggattgcaaagttc
gcctttgactatgccaccaagaaggggcggggcaaggtcactgctgtccacaaggccaac
atcatgaaacttggggatgggttgttcctgcagtgctgtgaggaagttgctgaactgtac
cccaaaatcaaatttgagacaatgatcatagacaactgctgcatgcagctggtgcagaat
ccttaccagtttgatgtgcttgtgatgcccaatctctatgggaacattattgacaatctg
gctgctggcctggttgggggagctggtgtggtccctggtgagagctatagtgcagaatac
gcagtctttgagacgggtgcccggcacccatttgcccaggcagtgggcaggaatatagcc
aatcccacggccatgctgctgtcggcttccaacatgctgcggcatcttaatcttgagtat
cactccagcatgatcgcagatgcggtgaagaaggtgatcaaagttggcaaggtgcggact
cgagacatgggcggctacagcaccacaaccgacttcatcaagtctgtcatcggtcacctg
cagactaaagggagctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (32)   
   RefSeq(nuc) (8)   
   GenBank (12)   
   EMBL (12)   
3D Structure (9)   
   PDB (9)   
Protein domain (2)   
   Pfam (2)   
All databases (89)   

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