KEGG   Homo sapiens (human): 343450
Entry
343450            CDS       T01001                                 
Symbol
KCNT2, DEE57, EIEE57, KCa4.2, SLICK, SLO2.1
Name
(RefSeq) potassium sodium-activated channel subfamily T member 2
  KO
K04947  potassium channel subfamily T member 2
Organism
hsa  Homo sapiens (human)
Disease
H00606  Early infantile epileptic encephalopathy
Drug target
Clofilium phosphate: D03547
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    343450 (KCNT2)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   343450 (KCNT2)
SSDB
Motif
Pfam: BK_channel_a Ion_trans_2 Ion_trans Anophelin
Other DBs
NCBI-GeneID: 343450
NCBI-ProteinID: NP_940905
OMIM: 610044
HGNC: 18866
Ensembl: ENSG00000162687
UniProt: Q6UVM3 A9LNM6
Position
1:complement(196225779..196608440)
AA seq 1135 aa
MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSL
RIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVSVALISLFETI
LLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENM
INDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTF
STVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEK
HVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYL
QGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQIL
KPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKM
YGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRREDNKNILLNPGP
RYIMNSTDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAID
LQDTSCRSASGPTLSLPTEGSKEIRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEE
MSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKL
IIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGS
IDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELT
HPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQS
FVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVPIGIYR
TESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARR
LSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTL
SYILINPSPDTRIELNDVVYLIRPDPLAYLPNSEPSRRNSICNVTGQDSREETQL
NT seq 3408 nt   +upstreamnt  +downstreamnt
atggttgatttggagagcgaagtgccccctctgcctcccaggtacaggtttcgagatttg
ctgctaggggaccaaggatggcaaaacgacgacagggtacaagttgaattctatatgaat
gaaaatacatttaaagaaagactaaaattatttttcataaaaaaccagagatcaagtcta
aggatacgcctgttcaatttttctctcaaattactaagctgcttattatacataatccga
gtactactagaaaacccttcacaaggaaatgaatggtctcatatcttttgggtgaacaga
agtctacctttgtggggcttacaggtttcagtggcattgataagtctgtttgaaacaata
ttacttggttatcttagttataagggaaacatctgggaacagattttacgaatacccttc
atcttggaaataattaatgcagttcccttcattatctcaatattctggccttccttaagg
aatctatttgtcccagtctttctgaactgttggcttgccaaacatgccttggaaaatatg
attaatgatctacacagagccattcagcgtacacagtctgcaatgtttaatcaagttttg
attttaatatctacattactatgccttatcttcacctgcatttgtgggatccaacatctg
gaacgaataggaaagaagctgaatctctttgactccctttatttctgcattgtgacgttt
tctactgtgggcttcggggatgtcactcctgaaacatggtcctccaagctttttgtagtt
gctatgatttgtgttgctcttgtggttctacccatacagtttgaacagctggcttatttg
tggatggagagacaaaagtcaggaggaaactatagtcgacatagagctcaaactgaaaag
catgtcgtcctgtgtgtcagctcactgaagattgatttacttatggattttttaaatgaa
ttctatgctcatcctaggctccaggattattatgtggtgattttgtgtcctactgaaatg
gatgtacaggttcgaagggtactgcagattccaatgtggtcccaacgagttatctacctt
caaggttcagcccttaaagatcaagacctattgagagcaaagatggatgacgctgaggcc
tgttttattctcagtagccgttgtgaagtggataggacatcatctgatcaccaaacaatt
ttgagagcatgggctgtgaaagattttgctccaaattgtcctttgtatgtccagatatta
aagcctgaaaataaatttcacatcaaatttgctgatcatgttgtttgtgaagaagagttt
aaatacgccatgttagctttaaactgtatatgcccagcaacatctacacttattacacta
ctggttcatacctctagagggcaagaaggccagcaatcgccagaacaatggcagaagatg
tacggtagatgctccgggaatgaagtctaccacattgttttggaagaaagtacatttttt
gctgaatatgaaggaaagagttttacatatgcctctttccatgcacacaaaaagtttggc
gtctgcttgattggtgttaggagggaggataataaaaacattttgctgaatccaggtcct
cgatacattatgaattctacagacatatgcttttatattaatattaccaaagaagagaat
tcagcatttaaaaaccaagaccagcagagaaaaagcaatgtgtccaggtcgttttatcat
ggaccttccagattacctgtacatagcataattgccagcatgggtactgtggctatagac
ttgcaagatacaagctgtagatcagcaagtggccctaccctgtctcttcctacagaggga
agcaaagaaataagaagacctagcattgctcctgttttagaggttgcagatacatcatcg
attcaaacatgtgatcttctaagtgaccaatcagaagatgaaactacaccagatgaagaa
atgtcttcaaacttagagtatgctaaaggttacccaccttattctccatatataggaagt
tcacccactttttgtcatctccttcatgaaaaagtaccattttgctgcttaagattagac
aagagttgccaacataactactatgaggatgcaaaagcctatggattcaaaaataaacta
attatagttgcagctgaaacagctggaaatggattatataactttattgttcctctcagg
gcatattatagaccaaagaaagaacttaatcccatagtactgctattggataacccgcca
gatatgcattttctggatgcaatctgttggtttccaatggtttactacatggtgggctct
attgacaacctagatgacttactcaggtgtggagtgacttttgctgctaatatggtggtt
gtggataaagagagcaccatgagtgccgaggaagactacatggcagatgccaaaaccatt
gtgaacgtgcagacactcttcaggttgttttccagtctcagtattatcacagagctaact
caccccgccaacatgagattcatgcaattcagagccaaagactgttactctcttgctctt
tcaaaactggaaaagaaagaacgggagagaggctctaacttggcctttatgtttcgactg
ccttttgctgctgggagggtgtttagcatcagtatgttggacactctgctgtatcagtca
tttgtgaaggattatatgatttctatcacgagacttctgttgggactggacactacacca
ggatctgggtttctttgttctatgaaaatcactgcagatgacttatggatcagaacttat
gccagactttatcagaagttgtgttcttctactggagatgttcccattggaatctacagg
actgagtctcagaaacttactacatctgagtctcaaatatctatcagtgtagaagagtgg
gaagacaccaaagactccaaagaacaagggcaccaccgcagcaaccaccgcaactcaaca
tccagtgatcagtcggaccatcccttgctgcggagaaaaagcatgcagtgggcccgaaga
ctgagcagaaaaggcccaaaacactctggtaaaacagctgaaaaaataacccagcagcga
ctgaacctctacaggaggtcagaaagacaagagcttgctgaacttgtgaaaaatagaatg
aaacacttgggtctttctacagtgggatatgatgaaatgaatgatcatcaaagtaccctc
tcctacatcctgattaacccatctccagataccagaatagagctgaatgatgttgtatac
ttaattcgaccagatccactggcctaccttccaaacagtgagcccagtcgaagaaacagc
atctgcaatgtcactggtcaagattctcgggaggaaactcaactttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (30)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (59)   
   RefSeq(nuc) (35)   
   GenBank (12)   
   EMBL (12)   
Protein domain (4)   
   Pfam (4)   
All databases (118)   

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