KEGG   Homo sapiens (human): 3482
Entry
3482              CDS       T01001                                 
Symbol
IGF2R, CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR_300, MPR1, MPR300, MPRI
Name
(RefSeq) insulin like growth factor 2 receptor
  KO
K06564  insulin-like growth factor 2 receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa03266  Virion - Herpesvirus
hsa04142  Lysosome
hsa04144  Endocytosis
Disease
H00048  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    3482 (IGF2R)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3482 (IGF2R)
   04142 Lysosome
    3482 (IGF2R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3482 (IGF2R)
   04090 CD molecules [BR:hsa04090]
    3482 (IGF2R)
   04091 Lectins [BR:hsa04091]
    3482 (IGF2R)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   3482 (IGF2R)
CD molecules [BR:hsa04090]
 Proteins
  3482 (IGF2R)
Lectins [BR:hsa04091]
 P-type lectins
  3482 (IGF2R)
SSDB
Motif
Pfam: CIMR ATG27 Man-6-P_recep fn2
Other DBs
NCBI-GeneID: 3482
NCBI-ProteinID: NP_000867
OMIM: 147280
HGNC: 5467
Ensembl: ENSG00000197081
UniProt: P11717
Structure
Position
6:159969082..160111504
AA seq 2491 aa
MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKN
NVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQ
GTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEE
LRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGH
QAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKL
TAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYL
FYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDEC
SSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDG
KKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAV
DKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTS
GEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFY
INVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERH
TPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDL
SSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGS
FTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNS
HPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSG
IGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFIT
LTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPS
PVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVG
SCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQ
LQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFR
VCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCH
KVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFD
LSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRV
RDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDCEYTFAW
PTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCP
PGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEARP
TNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESE
DDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEI
YLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVR
MDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSG
TKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIE
SRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFE
WKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCS
ERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTV
GRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRA
SGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDG
DLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPL
GVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLT
TCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALS
SLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKAR
KGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI
NT seq 7476 nt   +upstreamnt  +downstreamnt
atgggggccgccgccggccggagcccccacctggggcccgcgcccgcccgccgcccgcag
cgctctctgctcctgctgcagctgctgctgctcgtcgctgccccggggtccacgcaggcc
caggccgccccgttccccgagctgtgcagttatacatgggaagctgttgataccaaaaat
aatgtactttataaaatcaacatctgtggaagtgtggatattgtccagtgcgggccatca
agtgctgtttgtatgcacgacttgaagacacgcacttatcattcagtgggtgactctgtt
ttgagaagtgcaaccagatctctcctggaattcaacacaacagtgagctgtgaccagcaa
ggcacaaatcacagagtccagagcagcattgccttcctgtgtgggaaaaccctgggaact
cctgaatttgtaactgcaacagaatgtgtgcactactttgagtggaggaccactgcagcc
tgcaagaaagacatatttaaagcaaataaggaggtgccatgctatgtgtttgatgaagag
ttgaggaagcatgatctcaatcctctgatcaagcttagtggtgcctacttggtggatgac
tccgatccggacacttctctattcatcaatgtttgtagagacatagacacactacgagac
ccaggttcacagctgcgggcctgtccccccggcactgccgcctgcctggtaagaggacac
caggcgtttgatgttggccagccccgggacggactgaagctggtgcgcaaggacaggctt
gtcctgagttacgtgagggaagaggcaggaaagctagacttttgtgatggtcacagccct
gcggtgactattacatttgtttgcccgtcggagcggagagagggcaccattcccaaactc
acagctaaatccaactgccgctatgaaattgagtggattactgagtatgcctgccacaga
gattacctggaaagtaaaacttgttctctgagcggcgagcagcaggatgtctccatagac
ctcacaccacttgcccagagcggaggttcatcctatatttcagatggaaaagaatatttg
ttttatttgaatgtctgtggagaaactgaaatacagttctgtaataaaaaacaagctgca
gtttgccaagtgaaaaagagcgatacctctcaagtcaaagcagcaggaagataccacaat
cagaccctccgatattcggatggagacctcaccttgatatattttggaggtgatgaatgc
agctcagggtttcagcggatgagcgtcataaactttgagtgcaataaaaccgcaggtaac
gatgggaaaggaactcctgtattcacaggggaggttgactgcacctacttcttcacatgg
gacacggaatacgcctgtgttaaggagaaggaagacctcctctgcggtgccaccgacggg
aagaagcgctatgacctgtccgcgctggtccgccatgcagaaccagagcagaattgggaa
gctgtggatggcagtcagacggaaacagagaagaagcattttttcattaatatttgtcac
agagtgctgcaggaaggcaaggcacgagggtgtcccgaggacgcggcagtgtgtgcagtg
gataaaaatggaagtaaaaatctgggaaaatttatttcctctcccatgaaagagaaagga
aacattcaactctcttattcagatggtgatgattgtggtcatggcaagaaaattaaaact
aatatcacacttgtatgcaagccaggtgatctggaaagtgcaccagtgttgagaacttct
ggggaaggcggttgcttttatgagtttgagtggcacacagctgcggcctgtgtgctgtct
aagacagaaggggagaactgcacggtctttgactcccaggcagggttttcttttgactta
tcacctctcacaaagaaaaatggtgcctataaagttgagacaaagaagtatgacttttat
ataaatgtgtgtggcccggtgtctgtgagcccctgtcagccagactcaggagcctgccag
gtggcaaaaagtgatgagaagacttggaacttgggtctgagtaatgcgaagctttcatat
tatgatgggatgatccaactgaactacagaggcggcacaccctataacaatgaaagacac
acaccgagagctacgctcatcacctttctctgtgatcgagacgcgggagtgggcttccct
gaatatcaggaagaggataactccacctacaacttccggtggtacaccagctatgcctgc
ccggaggagcccctggaatgcgtagtgaccgacccctccacgctggagcagtacgacctc
tccagtctggcaaaatctgaaggtggccttggaggaaactggtatgccatggacaactca
ggggaacatgtcacgtggaggaaatactacattaacgtgtgtcggcctctgaatccagtg
ccgggctgcaaccgatatgcatcggcttgccagatgaagtatgaaaaagatcagggctcc
ttcactgaagtggtttccatcagtaacttgggaatggcaaagaccggcccggtggttgag
gacagcggcagcctccttctggaatacgtgaatgggtcggcctgcaccaccagcgatggc
agacagaccacatataccacgaggatccatctcgtctgctccaggggcaggctgaacagc
caccccatcttttctctcaactgggagtgtgtggtcagtttcctgtggaacacagaggct
gcctgtcccattcagacaacgacggatacagaccaggcttgctctataagggatcccaac
agtggatttgtgtttaatcttaatccgctaaacagttcgcaaggatataacgtctctggc
attgggaagatttttatgtttaatgtctgcggcacaatgcctgtctgtgggaccatcctg
ggaaaacctgcttctggctgtgaggcagaaacccaaactgaagagctcaagaattggaag
ccagcaaggccagtcggaattgagaaaagcctccagctgtccacagagggcttcatcact
ctgacctacaaagggcctctctctgccaaaggtaccgctgatgcttttatcgtccgcttt
gtttgcaatgatgatgtttactcagggcccctcaaattcctgcatcaagatatcgactct
gggcaagggatccgaaacacttactttgagtttgaaaccgcgttggcctgtgttccttct
ccagtggactgccaagtcaccgacctggctggaaatgagtacgacctgactggcctaagc
acagtcaggaaaccttggacggctgttgacacctctgtcgatgggagaaagaggactttc
tatttgagcgtttgcaatcctctcccttacattcctggatgccagggcagcgcagtgggg
tcttgcttagtgtcagaaggcaatagctggaatctgggtgtggtgcagatgagtccccaa
gccgcggcgaatggatctttgagcatcatgtatgtcaacggtgacaagtgtgggaaccag
cgcttctccaccaggatcacgtttgagtgtgctcagatatcgggctcaccagcatttcag
cttcaggatggttgtgagtacgtgtttatctggagaactgtggaagcctgtcccgttgtc
agagtggaaggggacaactgtgaggtgaaagacccaaggcatggcaacttgtatgacctg
aagcccctgggcctcaacgacaccatcgtgagcgctggcgaatacacttattacttccgg
gtctgtgggaagctttcctcagacgtctgccccacaagtgacaagtccaaggtggtctcc
tcatgtcaggaaaagcgggaaccgcagggatttcacaaagtggcaggtctcctgactcag
aagctaacttatgaaaatggcttgttaaaaatgaacttcacggggggggacacttgccat
aaggtttatcagcgctccacagccatcttcttctactgtgaccgcggcacccagcggcca
gtatttctaaaggagacttcagattgttcctacttgtttgagtggcgaacgcagtatgcc
tgcccacctttcgatctgactgaatgttcattcaaagatggggctggcaactccttcgac
ctctcgtccctgtcaaggtacagtgacaactgggaagccatcactgggacgggggacccg
gagcactacctcatcaatgtctgcaagtctctggccccgcaggctggcactgagccgtgc
cctccagaagcagccgcgtgtctgctgggtggctccaagcccgtgaacctcggcagggta
agggacggacctcagtggagagatggcataattgtcctgaaatacgttgatggcgactta
tgtccagatgggattcggaaaaagtcaaccaccatccgattcacctgcagcgagagccaa
gtgaactccaggcccatgttcatcagcgccgtggaggactgtgagtacacctttgcctgg
cccacagccacagcctgtcccatgaagagcaacgagcatgatgactgccaggtcaccaac
ccaagcacaggacacctgtttgatctgagctccttaagtggcagggcgggattcacagct
gcttacagcgagaaggggttggtttacatgagcatctgtggggagaatgaaaactgccct
cctggcgtgggggcctgctttggacagaccaggattagcgtgggcaaggccaacaagagg
ctgagatacgtggaccaggtcctgcagctggtgtacaaggatgggtccccttgtccctcc
aaatccggcctgagctataagagtgtgatcagtttcgtgtgcaggcctgaggccaggcca
accaataggcccatgctcatctccctggacaagcagacatgcactctcttcttctcctgg
cacacgccgctggcctgcgagcaagcgaccgaatgttccgtgaggaatggaagctctatt
gttgacttgtctccccttattcatcgcactggtggttatgaggcttatgatgagagtgag
gatgatgcctccgataccaaccctgatttctacatcaatatttgtcagccactaaatccc
atgcacggagtgccctgtcctgccggagccgctgtgtgcaaagttcctattgatggtccc
cccatagatatcggccgggtagcaggaccaccaatactcaatccaatagcaaatgagatt
tacttgaattttgaaagcagtactccttgcttagcggacaagcatttcaactacacctcg
ctcatcgcgtttcactgtaagagaggtgtgagcatgggaacgcctaagctgttaaggacc
agcgagtgcgactttgtgttcgaatgggagactcctgtcgtctgtcctgatgaagtgagg
atggatggctgtaccctgacagatgagcagctcctctacagcttcaacttgtccagcctt
tccacgagcacctttaaggtgactcgcgactcgcgcacctacagcgttggggtgtgcacc
tttgcagtcgggccagaacaaggaggctgtaaggacggaggagtctgtctgctctcaggc
accaagggggcatcctttggacggctgcaatcaatgaaactggattacaggcaccaggat
gaagcggtcgttttaagttacgtgaatggtgatcgttgccctccagaaaccgatgacggc
gtcccctgtgtcttccccttcatattcaatgggaagagctacgaggagtgcatcatagag
agcagggcgaagctgtggtgtagcacaactgcggactacgacagagaccacgagtggggc
ttctgcagacactcaaacagctaccggacatccagcatcatatttaagtgtgatgaagat
gaggacattgggaggccacaagtcttcagtgaagtgcgtgggtgtgatgtgacatttgag
tggaaaacaaaagttgtctgccctccaaagaagttggagtgcaaattcgtccagaaacac
aaaacctacgacctgcggctgctctcctctctcaccgggtcctggtccctcgtccacaac
ggagtctcgtactatataaatctgtgccagaaaatatataaagggcccctgggctgctct
gaaagggccagcatttgcagaaggaccacaactggtgacgtccaggtcctgggactcgtt
cacacgcagaagctgggtgtcataggtgacaaagttgttgtcacgtactccaaaggttat
ccgtgtggtggaaataagaccgcatcctccgtgatagaattgacctgtacaaagacggtg
ggcagacctgcattcaagaggtttgatatcgacagctgcacttactacttcagctgggac
tcccgggctgcctgcgccgtgaagcctcaggaggtgcagatggtgaatgggaccatcacc
aaccctataaatggcaagagcttcagcctcggagatatttattttaagctgttcagagcc
tctggggacatgaggaccaatggggacaactacctgtatgagatccaactttcctccatc
acaagctccagaaacccggcgtgctctggagccaacatatgccaggtgaagcccaacgat
cagcacttcagtcggaaagttggaacctctgacaagaccaagtactaccttcaagacggc
gatctcgatgtcgtgtttgcctcttcctctaagtgcggaaaggataagaccaagtctgtt
tcttccaccatcttcttccactgtgaccctctggtggaggacgggatccccgagttcagt
cacgagactgccgactgccagtacctcttctcttggtacacctcagccgtgtgtcctctg
ggggtgggctttgacagcgagaatcccggggacgacgggcagatgcacaaggggctgtca
gaacggagccaggcagtcggcgcggtgctcagcctgctgctggtggcgctcacctgctgc
ctgctggccctgttgctctacaagaaggagaggagggaaacagtgataagtaagctgacc
acttgctgtaggagaagttccaacgtgtcctacaaatactcaaaggtgaataaggaagaa
gagacagatgagaatgaaacagagtggctgatggaagagatccagctgcctcctccacgg
cagggaaaggaagggcaggagaacggccatattaccaccaagtcagtgaaagccctcagc
tccctgcatggggatgaccaggacagtgaggatgaggttctgaccatcccagaggtgaaa
gttcactcgggcaggggagctggggcagagagctcccacccagtgagaaacgcacagagc
aatgcccttcaggagcgtgaggacgatagggtggggctggtcaggggtgagaaggcgagg
aaagggaagtccagctctgcacagcagaagacagtgagctccaccaagctggtgtccttc
catgacgacagcgacgaggacctcttacacatctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (77)   
   KEGG ORTHOLOGY (1)   
   RefGene (71)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (3)   
   GenBank (8)   
   EMBL (8)   
3D Structure (24)   
   PDB (24)   
Protein domain (4)   
   Pfam (4)   
All databases (138)   

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