KEGG   Homo sapiens (human): 353376
Entry
353376            CDS       T01001                                 
Symbol
TICAM2, MyD88-4, TICAM-2, TIRAP3, TIRP, TRAM
Name
(RefSeq) TIR domain containing adaptor molecule 2
  KO
K05409  TRIF-related adaptor molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa04064  NF-kappa B signaling pathway
hsa04217  Necroptosis
hsa04620  Toll-like receptor signaling pathway
hsa05133  Pertussis
hsa05161  Hepatitis B
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05417  Lipid and atherosclerosis
Network
nt06162  Hepatitis B virus (HBV)
nt06263  Hepatocellular carcinoma
nt06517  TLR signaling
nt06527  Necroptosis
  Element
N00553  TLR4-IRF3/7 signaling pathway
N00554  HBV HBe to TLR4-IRF3/7 signaling pathway
N01634  TLR4-RIPK3 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    353376 (TICAM2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    353376 (TICAM2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    353376 (TICAM2)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    353376 (TICAM2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    353376 (TICAM2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    353376 (TICAM2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    353376 (TICAM2)
SSDB
Motif
Pfam: TIR_2 TIR
Other DBs
NCBI-GeneID: 353376
NCBI-ProteinID: NP_067681
OMIM: 608321
HGNC: 21354
Ensembl: ENSG00000243414
UniProt: Q86XR7
Structure
Position
5:complement(115578496..115602479)
AA seq 235 aa
MGIGKSKINSCPLSLSWGKRHSVDTSPGYHESDSKKSEDLSLCNVAEHSNTTEGPTGKQE
GAQSVEEMFEEEAEEEVFLKFVILHAEDDTDEALRVQNLLQDDFGIKPGIIFAEMPCGRQ
HLQNLDDAVNGSAWTILLLTENFLRDTWCNFQFYTSLMNSVNRQHKYNSVIPMRPLNNPL
PRERTPFALQTINALEEESRGFPTQVERIFQESVYKTQQTIWKETRNMVQRQFIA
NT seq 708 nt   +upstreamnt  +downstreamnt
atgggtatcgggaagtctaaaataaattcctgccctctttctctctcttggggtaaaagg
cacagtgtggatacaagtccaggatatcatgagtcagattccaagaagtctgaagatcta
tccttgtgtaatgttgctgagcacagcaatacaacagaggggccaacaggaaagcaggag
ggagctcagagcgtggaagagatgtttgaagaagaagctgaagaagaggtgttcctcaaa
tttgtgatattgcatgcagaagatgacacagatgaagccctcagagtccagaatctgcta
caagatgactttggtatcaaacccggaataatctttgctgagatgccatgtggcagacag
catttacagaatttagatgatgctgtaaatgggtctgcatggacaatcttattactgact
gaaaactttttaagagatacttggtgtaatttccagttctatacgtccctaatgaactcc
gttaacaggcagcataaatacaactctgttatacccatgcggcccctgaacaatcccctt
ccccgagaaaggactccctttgccctccaaaccatcaatgccttagaggaagaaagtcgt
ggatttcctacacaagtagaaagaatttttcaggagtctgtgtataagacacaacaaact
atatggaaagagacaagaaatatggtacaaagacaatttattgcctga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (7)   
Network (7)   
   KEGG NETWORK (7)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (31)   
   RefSeq(nuc) (1)   
   GenBank (15)   
   EMBL (15)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (62)   

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