KEGG   Homo sapiens (human): 3590
Entry
3590              CDS       T01001                                 
Symbol
IL11RA, CRSDA
Name
(RefSeq) interleukin 11 receptor subunit alpha
  KO
K05056  interleukin 11 receptor alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Network
nt06518  JAK-STAT signaling
  Element
N01556  IL6 family to Jak-STAT signaling pathway
Disease
H02254  Craniosynostosis and dental anomalies
Drug target
Oprelvekin: D05266
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    3590 (IL11RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3590 (IL11RA)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    3590 (IL11RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    3590 (IL11RA)
Cytokine receptors [BR:hsa04050]
 Interleukin receptor families
  IL6/12 receptor family
   3590 (IL11RA)
SSDB
Motif
Pfam: Ig_3 ig Ig_2 EpoR_lig-bind I-set
Other DBs
NCBI-GeneID: 3590
NCBI-ProteinID: NP_001136256
OMIM: 600939
HGNC: 5967
Ensembl: ENSG00000137070
UniProt: Q14626 Q5VZ79
Structure
Position
9:34652185..34661902
AA seq 422 aa
MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWF
RDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC
QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARC
VVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASW
TYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD
AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHR
DSVEQVAVLASLGILSFLGLVAGALALGLWLRLRRGGKDGSPKPGFLASVIPVDRRPGAP
NL
NT seq 1269 nt   +upstreamnt  +downstreamnt
atgagcagcagctgctcagggctgagcagggtcctggtggccgtggctacagccctggtg
tctgcctcctccccctgcccccaggcctggggccccccaggggtccagtatgggcagcca
ggcaggtccgtgaagctgtgttgtcctggagtgactgccggggacccagtgtcctggttt
cgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaactggtc
ctggcccaggcagacagcactgatgagggcacctacatctgccagaccctggatggtgca
cttgggggcacagtgaccctgcagctgggctaccctccagcccgccctgttgtctcctgc
caagcagccgactatgagaacttctcttgcacttggagtcccagccagatcagcggttta
cccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagccagagg
aggagtccatccacagggccctggccatgcccacaggatcccctaggggctgcccgctgt
gttgtccacggggctgagttctggagccagtaccggattaatgtgactgaggtgaaccca
ctgggtgccagcacacgcctgctggatgtgagcttgcagagcatcttgcgccctgaccca
ccccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagccagctgg
acataccctgcctcctggccgtgccagccccacttcctgctcaagttccgtttgcagtac
cgtccggcgcagcatccagcctggtccacggtggagccagctggactggaggaggtgatc
acagatgctgtggctgggctgccccatgctgtacgagtcagtgcccgggactttctagat
gctggcacctggagcacctggagcccggaggcctggggaactccgagcactgggaccata
ccaaaggagataccagcatggggccagctacacacgcagccagaggtggagcctcaggtg
gacagccctgctcctccaaggccctccctccaaccacaccctcggctacttgatcacagg
gactctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggactg
gtggctggggccctggcactggggctctggctgaggctgagacggggtgggaaggatgga
tccccaaagcctgggttcttggcctcagtgattccagtggacaggcgtccaggagctcca
aacctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (26)   
   RefSeq(nuc) (4)   
   GenBank (11)   
   EMBL (11)   
3D Structure (4)   
   PDB (4)   
Protein domain (5)   
   Pfam (5)   
All databases (71)   

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