| Entry |
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| Symbol |
IMPDH1, IMPD, IMPD1, IMPDH-I, LCA11, RP10, sWSS2608
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| Name |
(RefSeq) inosine monophosphate dehydrogenase 1
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| KO |
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| Organism |
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| Pathway |
| hsa00983 | Drug metabolism - other enzymes |
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| Module |
| hsa_M00050 | Guanine ribonucleotide biosynthesis, IMP => GDP,GTP |
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| Disease |
| H00837 | Leber congenital amaurosis |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
3614 (IMPDH1)
09111 Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
3614 (IMPDH1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
3614 (IMPDH1)
Enzymes [BR:hsa01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.205 IMP dehydrogenase
3614 (IMPDH1)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
3614 (IMPDH1)
Exosomal proteins of breast cancer cells
3614 (IMPDH1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
7:complement(128392277..128409982)
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| AA seq |
514 aa
MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT
LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV
LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT
PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS
QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI
GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP
IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM
EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR
SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY |
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| NT seq |
1545 nt +upstreamnt +downstreamnt
atggcggactacctgatcagcggcggcaccggctacgtgcccgaggatgggctcaccgcg
cagcagctcttcgccagcgccgacggcctcacctacaacgacttcctgattctcccagga
ttcatagacttcatagctgatgaggtggacctgacctcagccctgacccggaagatcacg
ctgaagacgccactgatctcctcccccatggacactgtgacagaggctgacatggccatt
gccatggctctgatgggaggtattggtttcattcaccacaactgcaccccagagttccag
gccaacgaggtgcggaaggtcaagaagtttgaacagggcttcatcacggaccctgtggtg
ctgagcccctcgcacactgtgggcgatgtgctggaggccaagatgcggcatggcttctct
ggcatccccatcactgagacgggcaccatgggcagcaagctggtgggcatcgtcacctcc
cgagacatcgactttcttgctgagaaggaccacaccaccctcctcagtgaggtgatgacg
ccaaggattgaactggtggtggctccagcaggtgtgacgttgaaagaggcaaatgagatc
ctgcagcgtagcaagaaagggaagctgcctatcgtcaatgattgcgatgagctggtggcc
atcatcgcccgcaccgacctgaagaagaaccgagactaccctctggcctccaaggattcc
cagaagcagctgctctgtggggcagctgtgggcacccgtgaggatgacaaataccgtctg
gacctgctcacccaggcgggcgtcgacgtcatagtcttggactcgtcccaagggaattcg
gtgtatcagatcgccatggtgcattacatcaaacagaagtacccccacctccaggtgatt
ggggggaacgtggtgacagcagcccaggccaagaacctgattgatgctggtgtggacggg
ctgcgcgtgggcatgggctgcggctccatctgcatcacccaggaagtgatggcctgtggt
cggccccagggcactgctgtgtacaaggtggctgagtatgcccggcgctttggtgtgccc
atcatagccgatggcggcatccagaccgtgggacacgtggtcaaggccctggcccttgga
gcctccacagtgatgatgggctccctgctggccgccactacggaggcccctggcgagtac
ttcttctcagacggggtgcggctcaagaagtaccggggcatgggctcactggatgccatg
gagaagagcagcagcagccagaaacgatacttcagcgagggggataaagtgaagatcgcg
cagggtgtctcgggctccatccaggacaaaggatccattcagaagttcgtgccctacctc
atagcaggcatccaacacggctgccaggatatcggggcccgcagcctgtctgtccttcgg
tccatgatgtactcaggagagctcaagtttgagaagcggaccatgtcggcccagattgag
ggtggtgtccatggcctgcactcttacgaaaagcggctgtactga |
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