KEGG   Homo sapiens (human): 3633
Entry
3633              CDS       T01001                                 
Symbol
INPP5B, 5PTase
Name
(RefSeq) inositol polyphosphate-5-phosphatase B
  KO
K01099  inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    3633 (INPP5B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    3633 (INPP5B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    3633 (INPP5B)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.36  phosphoinositide 5-phosphatase
     3633 (INPP5B)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    3633 (INPP5B)
 Endocytosis
  Clathrin-mediated endocytosis
   Inositol 5-phosphatases
    3633 (INPP5B)
  Rab GTPases and associated proteins
   Rab associated proteins
    3633 (INPP5B)
 Protein recycling
   Other Rab GTPase associated proteins
    3633 (INPP5B)
 Endosome - Golgi transport
   Rab associated proteins
    3633 (INPP5B)
SSDB
Motif
Pfam: INPP5B_PH OCRL-like_ASH RhoGAP
Other DBs
NCBI-GeneID: 3633
NCBI-ProteinID: NP_005531
OMIM: 147264
HGNC: 6077
Ensembl: ENSG00000204084
UniProt: P32019
Structure
Position
1:complement(37860697..37947057)
AA seq 913 aa
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRM
AITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRM
FLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGGS
NFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQK
FGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVG
FQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAY
ISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICS
RMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKI
QVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQS
HMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQ
NVKYMQLKVESFTIHNGQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLEL
FVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILD
LPLETISELTLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEF
EHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVI
STLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKLDMTEKKK
AQEFIHQFLCNPL
NT seq 2742 nt   +upstreamnt  +downstreamnt
atggaccagtctgtggcaatccaggagacgctggctgagggggaatactgcgtcatcgcg
gtgcaaggtgtgctgtgtgagggggacagccggcagagccgcctcctgggactcgtgcgc
taccgcctggagcacggcggccaggaacacgctctcttcctctatacgcaccggaggatg
gccattaccggggacgatgtctctctggaccagatagtgccagtctcgcgggattttacg
ctggaagaagtgtccccagatggtgaactctacatccttggctcagatgtgaccgtccag
ctggacacagcagagcttagcctcgtattccaactgccctttggttcacaaaccaggatg
ttcctccacgaagttgccagggcctgtccaggcttcgattctgcgacccgggatcctgaa
ttcctgtggctgtctcggtataggtgcgcagagctggagctggagatgccaacgccgcgc
ggttgtaactcggccctagttacctggccagggtacgcgacaattggcggaggtggttct
aactttgatggtttgagaccaaatgggaagggagtgcctatggaccaaagctccaggggt
caagataaaccagaaagcttgcaaccaagacagaataaatccaagtccgaaattactgac
atggttcgctcctccactatcacagtgtcggacaaggctcatattttatccatgcagaag
tttggactgcgagatacaattgtgaaatcacatctactacagaaagaagaggattacacc
tatatccagaacttcaggttttttgcgggaacatacaatgtaaatgggcagtcccccaaa
gaatgcctccggctgtggctgagcaatggtatccaggccccagatgtctattgtgtaggg
ttccaggagcttgatctgagtaaggaagcttttttctttcacgataccccaaaggaggaa
gagtggttcaaagctgtgtcagagggtcttcatccagatgccaaatatgcaaaggtgaag
cttatccgactggttgggattatgctgctgttatatgtcaaacaggagcatgcagcttat
atctcagaagtggaagccgagactgtggggacaggaatcatggggaggatgggcaacaag
ggaggcgtggcgatcaggttccagttccacaacaccagcatctgcgttgtgaattctcac
ttggcagcccacattgaagagtatgagaggaggaaccaggactataaggacatttgttct
cgaatgcagttttgtcagcctgacccaagccttccccctctcaccatcagcaaccatgat
gtgatcttgtggctgggggacctcaactacaggatagaagagctggatgtggaaaaagtg
aaaaagctcatcgaagagaaggactttcaaatgctgtatgcatatgatcagctgaaaatt
caggtggccgcaaagactgtctttgaaggcttcacagagggtgagctcacattccagcct
acttacaagtatgatacgggctctgacgactgggataccagtgagaagtgccgtgctcct
gcctggtgtgatcggattctctggaaagggaagaacatcactcagctgagttaccagagc
cacatggccctgaagaccagtgaccacaagcctgtcagctcagtgtttgacatcggggtg
agggtcgtaaatgacgagctttaccggaagacactggaggaaattgttcgctccctggat
aagatggaaaatgccaacattccttctgtgtccctgtccaagcgagagttctgttttcag
aatgtgaagtacatgcaattgaaagtagaatcctttacaattcataatggacaagtaccc
tgtcattttgaattcatcaacaagcctgatgaagagtcttactgtaagcagtggctgaat
gccaaccccagcagaggcttcctcctgccagattctgatgttgagattgacttggagctc
ttcgtaaataagatgacagctacaaagctcaactcgggtgaagacaaaattgaggacatt
ctggttctgcacttggacaggggaaaggattactttttgtctgtgtctgggaactacctg
cccagctgttttgggtctcccattcatacactgtgttacatgagagagccaatcttggac
ctaccacttgaaaccattagtgagctgactctgatgccagtatggactggagatgatggg
agccagttggatagccccatggaaatccccaaagagctctggatgatggttgattacctg
taccgaaatgctgtccagcaggaagatctgtttcagcaaccaggcctgaggtcagaattt
gaacatatcagggactgcttggatactggaatgattgataacctctctgccagcaatcat
tctgtagccgaagccctgctgcttttcctggagagccttccagagcctgtcatctgttac
agcacctaccataactgcttggagtgttctggcaactacacagcaagcaaacaggtcatt
tctactctccccatattccacaaaaatgtcttccactacttgatggcgtttttgcgagaa
ctgctgaaaaattcagcaaaaaatcatttggatgagaatattctagctagcatatttggc
agcttattgcttcgaaacccagctggtcaccaaaagcttgatatgacagagaagaagaag
gctcaagaatttattcaccagttcctctgcaacccactctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (50)   
   RefSeq(nuc) (28)   
   GenBank (11)   
   EMBL (11)   
3D Structure (5)   
   PDB (5)   
Protein domain (3)   
   Pfam (3)   
All databases (117)   

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