KEGG   Homo sapiens (human): 3663
Entry
3663              CDS       T01001                                 
Symbol
IRF5, SLEB10
Name
(RefSeq) interferon regulatory factor 5
  KO
K09446  interferon regulatory factor 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04620  Toll-like receptor signaling pathway
Network
nt06517  TLR signaling
  Element
N01543  TLR7/8/9-IRF5 signaling pathway
Disease
H00080  Systemic lupus erythematosus
H00630  Rheumatoid arthritis
H01227  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    3663 (IRF5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3663 (IRF5)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    3663 (IRF5)
SSDB
Motif
Pfam: IRF-3 IRF
Other DBs
NCBI-GeneID: 3663
NCBI-ProteinID: NP_001092097
OMIM: 607218
HGNC: 6120
Ensembl: ENSG00000128604
UniProt: Q13568
Structure
Position
7:128937032..128950038
AA seq 498 aa
MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD
NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV
CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQ
PPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLI
SPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFP
SPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNP
IQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVP
VAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPG
AGLGVGQGPWPMHPAGMQ
NT seq 1497 nt   +upstreamnt  +downstreamnt
atgaaccagtccatcccagtggctcccaccccaccccgccgcgtgcggctgaagccctgg
ctggtggcccaggtgaacagctgccagtacccagggcttcaatgggtcaacggggaaaag
aaattattctgcatcccctggaggcatgccacaaggcatggtcccagccaggacggagat
aacaccatcttcaaggcctgggccaaggagacagggaaatacaccgaaggcgtggatgaa
gccgatccggccaagtggaaggccaacctgcgctgtgcccttaacaagagccgggacttc
cgcctcatctacgacgggccccgggacatgccacctcagccctacaagatctacgaggtc
tgctccaatggccctgctcccacagactcccagccccctgaggattactcttttggtgca
ggagaggaggaggaagaagaggaagagctgcagaggatgttgccaagcctgagcctcaca
gaggatgtcaagtggccgcccactctgcagccgcccactctgcggccgcctactctgcag
ccgcccactctgcagccgcccgtggtgctgggtccccctgctccagaccccagccccctg
gctcctccccctggcaaccctgctggcttcagggagcttctctctgaggtcctggagcct
gggcccctgcctgccagcctgccccctgcaggcgaacagctcctgccagacctgctgatc
agcccccacatgctgcctctgaccgacctggagatcaagtttcagtaccgggggcggcca
ccccgggccctcaccatcagcaacccccatggctgccggctcttctacagccagctggag
gccacccaggagcaggtggaactcttcggccccataagcctggagcaagtgcgcttcccc
agccctgaggacatccccagtgacaagcagcgcttctacacgaaccagctgctggatgtc
ctggaccgcgggctcatcctccagctacagggccaggacctttatgccatccgcctgtgt
cagtgcaaggtgttctggagcgggccttgtgcctcagcccatgactcatgccccaacccc
atccagcgggaggtcaagaccaagcttttcagcctggagcattttctcaatgagctcatc
ctgttccaaaagggccagaccaacaccccaccacccttcgagatcttcttctgctttggg
gaagaatggcctgaccgcaaaccccgagagaagaagctcattactgtacaggtggtgcct
gtagcagctcgactgctgctggagatgttctcaggggagctatcttggtcagctgatagt
atccggctacagatctcaaacccagacctcaaagaccgcatggtggagcaattcaaggag
ctccatcacatctggcagtcccagcagcggttgcagcctgtggcccaggcccctcctgga
gcaggccttggtgttggccaggggccctggcctatgcacccagctggcatgcaataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (6)   
   KEGG DISEASE (3)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (120)   
   RefSeq(nuc) (16)   
   GenBank (52)   
   EMBL (52)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (177)   

Download RDF
DBGET integrated database retrieval system