KEGG   Homo sapiens (human): 3705
Entry
3705              CDS       T01001                                 
Symbol
ITPK1, ITRPK1
Name
(RefSeq) inositol-tetrakisphosphate 1-kinase
  KO
K00913  inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
Module
hsa_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    3705 (ITPK1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    3705 (ITPK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.134  inositol-tetrakisphosphate 1-kinase
     3705 (ITPK1)
    2.7.1.159  inositol-1,3,4-trisphosphate 5/6-kinase
     3705 (ITPK1)
SSDB
Motif
Pfam: Ins134_P3_kin Ins134_P3_kin_N RimK ATP-grasp_3
Other DBs
NCBI-GeneID: 3705
NCBI-ProteinID: NP_001136065
OMIM: 601838
HGNC: 6177
Ensembl: ENSG00000100605
UniProt: Q13572
Structure
Position
14:complement(92936914..93115925)
AA seq 414 aa
MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
GYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTCSASPG
CCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
NT seq 1245 nt   +upstreamnt  +downstreamnt
atgcagacctttctgaaagggaagagagttggctactggctgagcgagaagaaaatcaag
aagctgaatttccaggccttcgccgagctgtgcaggaagcgagggatggaggttgtgcag
ctgaaccttagccggccgatcgaggagcagggccccctggacgtcatcatccacaagctg
actgacgtcatccttgaagccgaccagaatgatagccagtccctggagctggtgcacagg
ttccaggagtacatcgatgcccaccctgagaccatcgtcctggacccgctccctgccatc
agaaccctgcttgaccgctccaagtcctatgagctcatccggaagattgaggcctacatg
gaagacgacaggatctgctcgccacccttcatggagctcacgagcctgtgcggggatgac
accatgcggctgctggagaagaacggcttgactttcccattcatttgcaaaaccagagtg
gctcatggcaccaactctcacgagatggctatcgtgttcaaccaggagggcctgaacgcc
atccagccaccctgcgtggtccagaatttcatcaaccacaacgccgtcctgtacaaggtg
ttcgtggttggcgagtcctacaccgtggtccagaggccctcactcaagaacttctccgca
ggcacatcagaccgtgagtccatcttcttcaacagccacaacgtgtcaaagccggagtcg
tcatcggtcctgacggagctggacaagatcgagggcgtgttcgagcggccgagcgacgag
gtcatccgggagctctcccgggccctgcggcaggcactgggcgtgtcactcttcggcatc
gacatcatcatcaacaaccagacagggcagcacgccgtcattgacatcaatgccttccca
ggctacgagggcgtgagcgagttcttcacagacctcctgaaccacatcgccactgtcctg
cagggccagagcacagccatggcagccacaggggacgtggccctgctgaggcacagcaag
cttctggccgagccggcgggcggcctggtgggcgagcggacatgcagcgccagccccggc
tgctgcggcagcatgatgggccaggacgcgccctggaaggctgaggccgacgcgggcggc
accgccaagctgccgcaccagagactcggctgcaacgccggcgtgtcgcccagcttccag
cagcattgtgtggcctccctggccaccaaggcctcctcccagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (36)   
   RefSeq(nuc) (10)   
   GenBank (13)   
   EMBL (13)   
3D Structure (3)   
   PDB (3)   
Protein domain (4)   
   Pfam (4)   
All databases (90)   

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