KEGG   Homo sapiens (human): 374462
Entry
374462            CDS       T01001                                 
Symbol
PTPRQ, DFNA73, DFNB84, DFNB84A, PTPGMC1, R-PTP-Q
Name
(RefSeq) protein tyrosine phosphatase receptor type Q
  KO
K16910  receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Disease
H00604  Deafness, autosomal dominant
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    374462 (PTPRQ)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    374462 (PTPRQ)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     374462 (PTPRQ)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    374462 (PTPRQ)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   374462 (PTPRQ)
SSDB
Motif
Pfam: fn3 Y_phosphatase Pur_ac_phosph_N fn3_2 PTP_tm Y_phosphatase3 PTPlike_phytase DSPc
Other DBs
NCBI-GeneID: 374462
NCBI-ProteinID: NP_001138498
OMIM: 603317
HGNC: 9679
Ensembl: ENSG00000139304
UniProt: A0A087WZU1
Position
12:80444235..80680273
AA seq 2299 aa
MDFLIIFLLLFIGTSETQVDVSNVVPGTRYDITISSISTTYTSPVTRIVTTNVTKPGPPV
FLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSKPDSLEVLLTN
LNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLPRQ
PNGKITSFKISVKHARSGIVVKDVSIRVEDILTGKLPECNENSESFLWSTASPSPTLGRV
TPPSRTTHSSSTLTQNEISSVWKEPISFVVTHLRPYTTYLFEVSAATTEAGYIDSTIVRT
PESVPEGPPQNCVTGNITGKSFSILWDPPTIVTGKFSYRVELYGPSGRILDNSTKDLKFA
FTNLTPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLAEVESTQVRITWKKP
RQPNGIINQYRVKVLVPETGIILENTLLTGNNEYINDPMAPEIVNIVEPMVGLYEGSAEM
SSDLHSLATFIYNSHPDKNFPARNRAEDQTSPVVTTRNQYITDIAAEQLSYVIRRLVPFT
EHMISVSAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGKIT
HYTIYAMELDTNRAFQITTIDNSFLITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRT
SEDEPESSPQDVEVIDVTADEIRLKWSPPEKPNGIIIAYEVLYKNIDTLYMKNTSTTDII
LRNLRPHTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNISSGEIELSF
LPPSSPNGIIQKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGV
RSAPISILTEEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEPNGIILYYTVYVWNRSSLKT
INVTETSLELSDLDYNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYANL
SSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTI
FSYYTFWLTASTSVGNGNKSSDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQP
NGLVFYYVSLILQQTPRHVRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQ
LYIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFITS
DNYIILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVW
LKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSAFTK
VGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTVERN
STKVSPQDHMYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIAFSD
VQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEET
VYGLKKFRWYRFQVAASTNAGYGNASNWISTKTLPGPPDGPPENVHVVATSPFSISISWS
EPAVITGPTCYLIDVKSVDNDEFNISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGNIS
AAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQAL
VYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAGPKVPMRITM
DIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVTETGAQHD
GNVTKWYDAYFNKARPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKIC
NGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILL
GTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRLLSYRKSI
KPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYN
NNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVM
LTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMTVRQ
CNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALDHLTQHI
NDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICFVNYSALQKM
DSLDAMEGDVELEWEETTM
NT seq 6900 nt   +upstreamnt  +downstreamnt
atggattttcttatcatttttcttttactttttattgggacttcagagacacaggttgat
gtttccaatgtcgttcctggtactaggtacgatataaccatctcttcaatttctacaaca
tacacctcacctgttactagaatagtgacaacaaatgtaacaaaaccagggcctccagtc
ttcctagccggggaaagagtcggatctgctgggattcttctgtcttggaatacaccacct
aatccaaatggaaggattatatcttacattgtcaaatataaggaagtttgtccgtggatg
caaacagtatatacacaagtcagatcaaagccagacagtctggaagttcttcttactaat
cttaatcctggaacaacatatgaaattaaggttgctgctgaaaacagtgctggcattgga
gtgtttagtgatccatttctcttccaaactgcagaaagtgctccaggaaaagtggtgaat
ctcacagttgaggcctacaacgcttcagcagttaagctgatttggtatttacctcggcaa
ccaaatggcaaaattaccagcttcaagattagtgtcaagcatgccagaagtgggatagta
gtgaaagatgtctcaatcagagtagaggacattttgactgggaaattgccagaatgcaat
gagaatagtgaatcttttttatggagtacagccagcccttctccaacccttggtagagtt
acacctccatcgcgtaccacacattcatcaagcacgttgacacagaatgagatcagctct
gtgtggaaagagcctatcagttttgtagtgacacacttgagaccttatacaacatatctt
tttgaagtttcagctgctacaactgaagcaggttatattgatagtacgattgtcagaaca
ccagaatcagtgcctgaaggaccaccacaaaactgcgtaacaggcaacatcacaggaaag
tccttttcaattttatgggacccaccaactatagtaacagggaaatttagttatagagtt
gaattatatggaccatcaggtcgcattttggataacagcacaaaagacctcaagtttgca
ttcactaacctaacaccatttacaatgtatgatgtctatattgcggctgaaaccagtgca
gggactgggcccaagtcaaatatttcagtattcactccaccagatgttccaggggcagtg
tttgatttacaacttgcagaggtagaatccacgcaagtaagaattacttggaagaaacca
cgacaaccaaatggaattattaaccaataccgagtgaaagtgctagttccagagacagga
ataattttggaaaatactttgctcactggaaataatgagtatataaatgaccccatggct
ccagaaattgtgaacatagtagagccaatggtaggattatatgagggttcagcagagatg
tcgtctgaccttcactcacttgctacatttatatataacagccatccagataaaaacttt
cctgcaaggaatagagctgaagaccagacttcaccagttgtaactacaaggaatcagtat
attactgacattgcagctgaacagctgtcttatgttatcaggagacttgtacctttcact
gagcacatgattagtgtatctgctttcaccatcatgggagaaggaccaccaacagttctc
agtgttaggacacgtcagcaagtgccaagctccattaaaattataaactataaaaatatt
agttcttcatctattttgttatattgggatcctccagaatatcccaatggaaaaataact
cactatacgatttatgcaatggaattggatacaaacagagcattccagataactaccata
gataacagctttctcataacagggttaaagaaatacacaaaatacaaaatgagagtggca
gcctcaacccacgttggagaaagttctttgtctgaagaaaatgacatctttgtgagaact
tcagaagatgaaccggaatcatcacctcaagatgtcgaagtaattgatgttaccgcagat
gaaataaggttgaagtggtcaccacccgaaaagcccaatgggatcattattgcttatgaa
gtgctatataaaaatatagatactttatatatgaagaacacatcaacaacagacataata
ttaaggaacttaagacctcacaccctctataacatttctgtaaggtcttacaccagattt
ggtcatggcaatcaggtatcttctttactctctgtaaggacttcggagactgtgcctgat
agtgcaccagaaaatatcacttacaaaaatatttcttctggagagattgagctatcattc
cttcccccaagtagtcccaatggaatcatacaaaaatatacaatttatctcaagagaagt
aatggaaatgaggaaagaactataaatacaacctctttaacccaaaacattaaagtactg
aagaaatatacccaatatatcattgaggtgtctgctagtacactcaaaggtgaaggagtt
cggagtgctcccataagtatactgacggaggaagatgctcctgattctccccctcaagac
ttctctgtaaaacagttgtctggtgtcacggtgaagttgtcatggcaaccacccctggag
ccaaatggaattatcctttattacacagtttatgtctggaatagatcatcattaaaaact
attaatgtcactgaaacatcattggagttatcagatttggattataatgttgaatacagt
gcttatgtaacagctagcaccagatttggtgatgggaaaacaagaagcaatatcattagc
tttcaaacaccagagggagcaccaagcgatcctcccaaagatgtttattatgcaaacctc
agttcttcatcaataattcttttctggacacctccttcaaaacctaatgggattatacaa
tattactctgtttattacagaaatacttcaggtacttttatgcagaattttacactccat
gaagtaaccaatgactttgacaatatgactgtatccacaattatagataaactgacaata
ttcagctactatacattttggttaacagcaagtacttcagttggaaatgggaataaaagc
agtgacatcattgaagtatacacagatcaagacatacctgaagggtttgttggaaacctg
acttacgaatccatttcgtcaactgcaataaatgtaagctgggtcccaccggctcaacca
aacggtctagtcttctactatgtttcactgatcttacagcagactcctcgccatgtgaga
ccacctcttgttacatatgagagaagcatatattttgataatctggaaaaatacactgat
tatatattaaaaattactccatcaacagaaaagggattctctgatacctatactgcccag
ctatacatcaagactgaagaagatgtcccagaaacttcaccaataatcaacacttttaaa
aacctttcctctacctcagttctcttatcatgggatcccccagtaaagccaaatggtgca
ataataagttatgatttaactttacaaggaccaaatgaaaattattctttcattacttct
gataattacataatattggaagagctttcaccatttacattatatagcttttttgctgcc
gcaagaactagaaaaggacttggtccttccagtattcttttcttttacacagatgagtca
gtgccgttagcacctccacaaaatttgactttaatcaactgtacttcagactttgtatgg
ctgaaatggagcccaagtcctcttccaggtggtattgttaaagtatatagttttaaaatt
catgaacatgaaactgacactatatattataagaatatatcaggatttaaaactgaagcc
aaacttgttggactggaaccagtcagcacctactctatccgtgtatctgcgttcaccaaa
gttggaaatggcaatcaatttagtaatgtagtaaaattcacaacccaagaatcagttcca
gatgtcgtgcagaatatgcagtgcatggcaactagctggcagtcagttttagtgaaatgg
gatccacccaaaaaggcaaatggaataataacgcagtatatggtaacagttgaaaggaat
tctacaaaagtttctccccaagatcacatgtacactttcataaagcttcttgccaatacc
tcatatgtctttaaagtaagagcttcaacctcagctggtgaaggtgatgaaagcacatgc
catgtcagcacactacctgaaacagttcccagtgttcccacaaatattgctttttctgat
gttcagtcaactagtgcaacattgacatggataagacctgacactatccttggctacttt
caaaattacaaaattaccactcaacttcgtgctcaaaaatgcaaagaatgggaatccgaa
gaatgtgttgaatatcaaaaaattcaatacctctatgaagctcacttaactgaagagaca
gtatatggattaaagaaatttagatggtatagattccaagtggctgccagcaccaatgct
ggctatggcaatgcttcaaactggatttctacaaaaactctgcctggccctccagatggt
cctcctgaaaatgttcatgtagtagcaacatcaccttttagcatcagcataagctggagt
gaacctgctgtcattactggaccaacatgttatctgattgatgtcaaatcggtagataat
gatgaatttaatatatccttcatcaagtcaaatgaagaaaataaaaccatagaaattaaa
gatttagaaatattcacaaggtattctgtagtgatcactgcatttactgggaacattagt
gctgcatatgtagaagggaagtcaagtgctgaaatgattgttactactttagaatcagcc
ccaaaggacccacctaacaacatgacatttcagaagataccagatgaagttacaaaattt
caattaacgttccttcctccttctcaacctaatggaaatatccaagtatatcaagctctg
gtttaccgagaagatgatcctactgctgtccagattcacaacctcagtattatacagaaa
accaacacattcgtcattgcaatgctagaaggactaaaaggtggacatacatacaatatc
agtgtttacgcagtcaatagtgctggtgcaggtccaaaggttccgatgagaataaccatg
gatatcaaagctccagcacgaccaaaaaccaaaccaacccctatttatgatgccacagga
aaactgcttgtgacttcaacaacaattacaatcagaatgccaatatgttactacagtgat
gatcatggaccaataaaaaatgtacaagtgcttgtgacagaaacaggagctcagcatgat
ggaaatgtaacaaagtggtatgatgcatattttaataaagcaaggccatattttacaaat
gaaggctttcctaaccctccatgtacagaaggaaagacaaagtttagtggcaatgaagaa
atctacatcataggtgctgataatgcatgcatgattcctggcaatgaagacaaaatttgc
aatggaccactgaaaccaaaaaagcaatacttatttaaatttagagctacaaatattatg
ggacaatttactgactctgattattctgaccctgttaagactttaggggaaggactttca
gaaagaaccgtagagatcattctttccgtcactttgtgtatcctttcaataattctcctt
ggaacagctatttttgcatttgcaagaattcgacagaagcagaaagaaggtggcacatac
tctcctcaggatgcagaaattattgacactaaattgaagctggatcagctcatcacagtg
gcagacctggaactgaaggacgagagattaacgcggttacttagttatagaaaatccatc
aagccaataagcaagaaatccttcctgcaacatgttgaagagctttgcacaaacaacaac
ctaaagtttcaagaagaattttcggaattaccaaaatttcttcaggatctttcttcaact
gatgctgatctgccttggaatagagcaaaaaaccgcttcccaaacataaaaccatataat
aataacagagtaaagctgatagctgacgctagtgttccaggttcggattatattaatgcc
agctatatttctggttatttatgtccaaatgaatttattgctactcaaggtccactacca
ggaacagttggagatttttggagaatggtgtgggaaaccagagcaaaaacattagtaatg
ctaacacagtgttttgaaaaaggacggatcagatgccatcagtattggccagaggacaac
aagccagttactgtctttggagatatagtgattacaaagctaatggaggatgttcaaata
gattggactatcagggatctgaaaattgaaaggcatggggattgcatgactgttcgacag
tgtaactttactgcctggccagagcatggggttcctgagaacagcgcccctctaattcac
tttgtgaagttggttcgagcaagcagggcacatgacaccacacctatgattgttcactgc
agtgctggagttggaagaactggagtttttattgctctggaccatttaacacaacatata
aatgaccatgattttgtggatatatatggactagtagctgaactgagaagtgaaagaatg
tgcatggtgcagaatctggcacagtatatctttttacaccagtgcattctggatctctta
tcaaataagggaagtaatcagcccatctgttttgttaactattcagcacttcagaagatg
gactctttggacgccatggaaggtgatgttgagcttgaatgggaagaaaccactatgtaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
Protein domain (8)   
   Pfam (8)   
All databases (85)   

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