KEGG   Homo sapiens (human): 3751
Entry
3751              CDS       T01001                                 
Symbol
KCND2, KV4.2, RK5
Name
(RefSeq) potassium voltage-gated channel subfamily D member 2
  KO
K04892  potassium voltage-gated channel Shal-related subfamily D member 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04726  Serotonergic synapse
Network
nt06462  Spinocerebellar ataxia
  Element
N00974  Transport of potassium
Drug target
Amifampridine: D10228 D10689<US>
Butamben (DG02875): D00730
Clofilium phosphate: D03547
Fampridine: D04127<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3751 (KCND2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3751 (KCND2)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, voltage-gated (Kv)
   3751 (KCND2)
SSDB
Motif
Pfam: Ion_trans DUF3399 BTB_2 Ion_trans_2 Shal-type BTB_3 PKD_channel
Other DBs
NCBI-GeneID: 3751
NCBI-ProteinID: NP_036413
OMIM: 605410
HGNC: 6238
Ensembl: ENSG00000184408
UniProt: Q9NZV8 A4D0V9
Structure
Position
7:120272908..120750337
AA seq 630 aa
MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQSSEDEQAFVSKSGSSFETQHHH
LLHCLEKTTNHEFVDEQVFEESCMEVATVNRPSSHSPSLSSQQGVTSTCCSRRHKKTFRI
PNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKMEECVKLNCEQPYVTTAIISI
PTPPVTTPEGDDRPESPEYSGGNIVRVSAL
NT seq 1893 nt   +upstreamnt  +downstreamnt
atggcggcgggggtggcagcgtggctgccttttgcaagggcagcggctatcgggtggatg
cctgtggcctcggggcctatgccggctcccccgaggcaggagaggaaaaggacccaagat
gctctcattgtgctgaatgtgagtggcacccgcttccagacgtggcaggacaccctggaa
cgttacccagacactctactgggcagttctgagagggactttttctaccacccagaaact
cagcagtatttctttgaccgtgacccagacatcttccgccacatcctgaatttctaccgc
actgggaagctccactatcctcgccacgagtgcatctctgcttacgatgaagaactggcc
ttctttggcctcatcccggaaatcatcggcgactgctgttatgaggagtacaaggatcgc
aggcgagagaacgccgagcgcctgcaggacgacgcggataccgacaccgctggggagagc
gccttgcccaccatgactgcaaggcagagggtctggagggccttcgagaacccccacacc
agcacgatggccctggtgttctactatgtcacggggtttttcattgccgtctctgtcatc
gcgaatgtggtggaaacagtgccgtgcggatcaagcccaggtcacattaaagaactgccc
tgtggagagcggtatgctgtggccttcttctgcttggacacggcctgcgtcatgatcttc
acagttgagtatttgcttcgcctggctgcagcgcctagtcgttaccgttttgtgcgtagt
gtcatgagtatcatcgacgtggtggccatcctgccttattacattgggctggtgatgaca
gacaatgaggacgtcagcggagcctttgtcacactccgagtcttccgggtcttcaggatc
tttaagttttcccgccactctcaaggcctgcgcatcctggggtacacactgaagagttgt
gcctcagaattgggcttcttgcttttctcgctcaccatggctatcatcatcttcgctaca
gttatgttctacgcagagaaggggtcttcggctagcaagttcaccagcatccctgcagcc
ttctggtataccatcgtcaccatgacaacactagggtatggtgacatggtgccaaaaacc
atagcagggaagatttttggttctatctgttcgctgagtggggtcttggtcattgctcta
cctgttccggtgattgtatccaacttcagtcgcatctaccaccagaatcaacgagcagac
aaacgaagggcacaaaagaaagctagactggccaggatccgggcagccaaaagcggaagc
gcaaatgcttacatgcagagcaaacggaatggtttactcagtaatcagctgcagtcctca
gaggatgagcaggcttttgttagcaaatccggctccagctttgaaacccagcaccaccac
ctgcttcactgcctggaaaaaaccacgaatcacgagtttgtggacgaacaagtctttgaa
gaaagctgcatggaagttgcaactgttaatcgtccttcaagtcacagtccttcactgtct
tcacaacaaggagtcaccagcacctgctgttcacgacgacacaaaaaaacttttcgcatc
ccaaatgccaatgtatcaggaagccatcaaggtagtatacaagaactcagcacgattcag
atcagatgtgtggagagaacacctctgtctaacagccgatccagtttaaatgccaaaatg
gaagagtgtgttaaactaaactgtgaacaaccttatgtgactacagcaataataagcatc
ccaacacctccagtaaccacaccagaaggagacgataggccagaatcccctgagtactca
ggaggaaatattgtcagagtttctgctttgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Drug (5)   
   KEGG DRUG (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (15)   
   RefSeq(nuc) (3)   
   GenBank (6)   
   EMBL (6)   
3D Structure (16)   
   PDB (16)   
Protein domain (7)   
   Pfam (7)   
All databases (67)   

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