KEGG   Homo sapiens (human): 375449
Entry
375449            CDS       T01001                                 
Symbol
MAST4
Name
(RefSeq) microtubule associated serine/threonine kinase family member 4
  KO
K08789  MAST-subfamily protein kinase [EC:2.7.11.37]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    375449 (MAST4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.37  MAST-subfamily protein kinase
     375449 (MAST4)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  MAST family [OT]
   375449 (MAST4)
SSDB
Motif
Pfam: DUF1908 Pkinase PK_Tyr_Ser-Thr PDZ_6 PDZ PDZ_2 ABC1 APH Kinase-like Tricorn_PDZ
Other DBs
NCBI-GeneID: 375449
NCBI-ProteinID: NP_001158136
OMIM: 618002
HGNC: 19037
Ensembl: ENSG00000069020
UniProt: O15021
Structure
Position
5:66596393..67169593
AA seq 2623 aa
MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE
HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE
ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP
VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSFCRTSNRKSLIGNGQS
PALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPS
STVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESIATENRCRNTPMRPRSRSLSPGR
SPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDNVLPLADGVLSFTHHQIIE
LARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPA
RLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAHLGNYDS
GTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKK
INKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMK
NMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLM
SMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGC
VPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQH
RFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQ
FSSCSHRFSKVFSSIDRITQNSAEEKEDSVDKTKSTTLPSTETLSWSSEYSEMQQLSTSN
SSDTESNRHKLSSGLLPKLAISTEGEQDEAASCPGDPHEEPGKPALPPEECAQEEPEVTT
PASTISSSTLSVGSFSEHLDQINGRSECVDSTDNSSKPSSEPASHMARQRLESTEKKKIS
GKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSAASASPHQ
PIVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGE
PVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESL
ERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDF
PSGTNSSQSSSPSSSAPNSPAGSGHIRPSTLHGLAPKLGGQRYRSGRRKSAGNIPLSPLA
RTPSPTPQPTSPQRSPSPLLGHSLGNSKIAQAFPSKMHSPPTIVRHIVRPKSAEPPRSPL
LKRVQSEEKLSPSYGSDKKHLCSRKHSLEVTQEEVQREQSQREAPLQSLDENVCDVPPLS
RARPVEQGCLKRPVSRKVGRQESVDDLDRDKLKAKVVVKKADGFPEKQESHQKSHGPGSD
LENFALFKLEEREKKVYPKAVERSSTFENKASMQEAPPLGSLLKDALHKQASVRASEGAM
SDGRVPAEHRQGGGDFRRAPAPGTLQDGLCHSLDRGISGKGEGTEKSSQAKELLRCEKLD
SKLANIDYLRKKMSLEDKEDNLCPVLKPKMTAGSHECLPGNPVRPTGGQQEPPPASESRA
FVSSTHAAQMSAVSFVPLKALTGRVDSGTEKPGLVAPESPVRKSPSEYKLEGRSVSCLKP
IEGTLDIALLSGPQASKTELPSPESAQSPSPSGDVRASVPPVLPSSSGKKNDTTSARELS
PSSLKMNKSYLLEPWFLPPSRGLQNSPAVSLPDPEFKRDRKGPHPTARSPGTVMESNPQQ
REGSSPKHQDHTTDPKLLTCLGQNLHSPDLARPRCPLPPEASPSREKPGLRESSERGPPT
ARSERSAARADTCREPSMELCFPETAKTSDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGG
KTNHKDGPGEARPPPRDNSSLHSAGIPCEKELGKVRRGVEPKPEALLARRSLQPPGIESE
KSEKLSSFPSLQKDGAKEPERKEQPLQRHPSSIPPPPLTAKDLSSPAARQHCSSPSHASG
REPGAKPSTAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVG
ATKGKEPATQSLGGSSREGKGHSKSGPDVFPATPGSQNKASDGIGQGEGGPSVPLHTDRA
PLDAKPQPTSGGRPLEVLEKPVHLPRPGHPGPSEPADQKLSAVGEKQTLSPKHPKPSTVK
DCPTLCKQTDNRQTDKSPSQPAANTDRRAEGKKCTEALYAPAEGDKLEAGLSFVHSENRL
KGAERPAAGVGKGFPEARGKGPGPQKPPTEADKPNGMKRSPSATGQSSFRSTALPEKSLS
CSSSFPETRAGVREASAASSDTSSAKAAGGMLELPAPSNRDHRKAQPAGEGRTHMTKSDS
LPSFRVSTLPLESHHPDPNTMGGASHRDRALSVTATVGETKGKDPAPAQPPPARKQNVGR
DVTKPSPAPNTDRPISLSNEKDFVVRQRRGKESLRSSPHKKAL
NT seq 7872 nt   +upstreamnt  +downstreamnt
atgggggagaaagtttcggaggcgccagagccggtgccccgcggctgcagtggccacggc
agccggactccagcctctgcgctggtcgccgcgtcctctccgggtgcttcctcggccgag
tcctcctcgggctcagaaactctgtcggaggaaggggagcccggcggcttctccagagag
catcagccgccgccgccgccgccgttgggaggcaccctgggcgcccgggcgcccgccgcg
tgggctccggcaagcgtgctgctggagcgcggagtccttgcgctgccgccgccgcttccc
ggaggagctgtgccgcccgcgccccggggcagcagcgcgtcccaggaggagcaggacgag
gagcttgaccacatattatcccctccacccatgccgtttcggaaatgcagcaacccagat
gtggcttctggccctggaaaatcactgaagtataaaagacagctgagtgaggatggaaga
cagctaaggcgagggagcctgggaggagccctgactgggaggtaccttcttccaaacccg
gtggcgggacaggcctggccggcctctgcagagacgtccaacctcgtgcgcatgcgcagc
caggccctgggccagtcggcgccctcgctcaccgccagcctgaaggagctgagtctcccc
agaagaggaagtttttgccgaacaagcaaccggaaaagcttaataggcaatgggcagtca
ccagcattgcctcgaccacactcacctctctctgctcatgcaggaaatagccctcaagat
agtccaagaaatttctcccccagtgcctcagcccatttttcatttgcacggaggactgat
ggacgccgctggtcgttggcttctctcccttcctctggctatgggacaaacacacccagc
tctacggtctcttcatcctgttcctcccaggagaagttgcatcagttaccataccaacca
acaccagacgagttacacttcttatcaaaacatttctgtaccaccgaaagcatcgccact
gagaacagatgcaggaacacgccgatgcgcccccgttcccgaagtctgagccctggacgt
tctcccgcctgctgtgaccatgaaataattatgatgaaccatgtctacaaagaaaggttc
ccaaaggctacagctcagatggaagaacgtctaaaggaaattatcaccagctactctcct
gacaacgttctacccttagcagatggagtgcttagtttcactcaccaccagattattgaa
ctggctcgagattgcttggataaatcccaccagggcctcatcacctcacgatacttcctt
gaattacagcacaaattagataagttgctacaggaggctcatgatcgttcagaaagtgga
gaattggcatttattaaacaactagttcgaaagatcctaattgttattgcccgccctgct
cggttattagagtgcctggaatttgatccggaagaattttactacctattggaagcagca
gaaggccatgccaaagaaggacagggtattaaaaccgacattcccaggtacatcattagc
caactgggactcaataaggatcccttggaagaaatggctcatttgggaaactacgatagt
gggacagcagaaacaccagaaacagatgaatcagtgagtagctctaatgcctccctgaaa
cttcgaaggaaacctcgggaaagtgattttgaaacgattaaattgattagcaatggagcc
tatggggcagtctactttgttcggcataaagaatcccggcagaggtttgccatgaagaag
attaataaacagaacctcatccttcgaaaccagatccagcaggcctttgtggagcgggat
atcctgacttttgcagaaaacccctttgttgtcagcatgtattgctcctttgaaacaagg
cgccacttgtgcatggtcatggaatatgtggaagggggagactgtgctactttaatgaaa
aacatgggtcctctccctgttgatatggccagaatgtactttgctgagacggtcttggcc
ttggaatatttacataattatggaattgtacacagggatttgaaaccagacaacttgttg
gttacctccatggggcacataaagctgacagattttggattatctaaggtgggactaatg
agcatgactaccaacctttacgagggtcatattgagaaggatgctagagagttcctggat
aaacaggtctgtggcacacctgaatacattgcaccagaagtgattctgaggcagggttat
ggaaagccggtggactggtgggccatggggattatcctctatgaatttctggttggatgc
gtgccattctttggggatactccagaggagctatttggacaagtcatcagtgatgagatc
aactggcctgagaaggatgaggcacccccacctgatgcccaggatctgattaccttactc
ctcaggcagaatcccctggagaggctgggaacaggtggtgcatatgaagtcaaacagcat
cgattcttccgttctttagactggaacagtttgctgagacagaaggcagaatttattccc
caactggaatctgaggatgacacaagttattttgatactcggtctgagaagtatcatcat
atggaaacggaggaagaagatgacacaaatgatgaagactttaatgtggaaataaggcag
ttttcttcatgttcacacaggttttcaaaagttttcagcagtatagatcgaatcactcag
aattcagcagaagagaaggaagactctgtggacaaaaccaaaagcaccaccttgccatcc
acagaaacactgagctggagttcagaatattctgaaatgcaacagctatcaacatccaac
tcttcagatactgaaagcaacagacataaactcagttctggcctacttcccaaactggct
atttcaacagagggagagcaagatgaagctgcctcctgccctggagacccccatgaggag
ccaggaaagccagcccttcctcctgaagagtgtgcccaggaggagcctgaggtcaccacc
ccagccagcaccatcagcagctccaccctgtcagttggcagtttttcagagcacttggat
cagataaatggacgaagcgagtgtgtggacagtacagataattcctcaaagccatccagt
gaacccgcttctcacatggctcggcagcgattagaaagcacagaaaaaaagaaaatctcg
gggaaagtcacaaagtccctctctgccagtgctctttccctcatgatcccaggagatatg
tttgctgtttcccctctgggaagtccaatgtctccccattccctgtcctcggacccttct
tcttcacgagattcctctcccagccgagattcctcagcagcttctgccagtccacatcag
ccgattgtgatccacagttcggggaagaactacggctttaccatccgagccatccgggtg
tatgtgggagacagtgacatctatacagtgcaccatatcgtctggaatgtagaagaagga
agtccggcatgccaggcaggactgaaggctggagatcttatcactcacatcaatggagaa
ccagtgcatggacttgtccacacagaagttatagaactcctactgaagagtgggaataag
gtgtcaatcactactaccccatttgaaaacacatcaatcaaaactggaccagccaggaga
aacagctataagagccggatggtgaggcggagcaagaaatccaagaagaaagaaagtctc
gaaaggaggagatctcttttcaaaaagctagccaagcagccttctcctttactccacacc
agccgaagtttctcctgcttgaacagatccctgtcatcgggtgagagcctcccaggttcc
cccactcatagcttgtctccccggtctccaacaccaagctaccgctccacccctgacttc
ccatctggtactaattcctcccagagcagctcccctagttctagtgcccccaattcccca
gcagggtccgggcacatccggcccagcactctccacggtcttgcacccaaactcggcggg
cagcggtaccggtccggaaggcgaaagtccgccggcaacatcccactgtccccgctggcc
cggacgccctctccaaccccgcaacccacctccccgcagcggtcaccatcccctcttctg
ggacactcactgggcaattccaagatcgcgcaagcctttcccagcaagatgcactccccg
cccaccatcgtcagacacatcgtgaggcccaagagtgcggagccccccaggtccccgctg
ctcaagcgcgtgcagtccgaggagaagctgtcgccctcttacggcagtgacaagaagcac
ctgtgctcccgcaagcacagcctggaggtgacccaagaggaggtgcagcgggagcagtcc
cagcgggaggcgccgctgcagagcctggatgagaacgtgtgcgacgtgccgccgctcagc
cgcgcccggccagtggagcaaggctgcctgaaacgcccagtctcccggaaggtgggccgc
caggagtctgtggacgacctggaccgcgacaagctgaaggccaaggtggtggtgaagaaa
gcagacggcttcccagagaaacaggaatcccaccagaaatcccatggacccgggagtgat
ttggaaaactttgctctgtttaagctggaagagagagagaagaaagtctatccgaaggct
gtggaaaggtcaagtacttttgaaaacaaagcgtctatgcaggaggcgccaccgctgggc
agcctgctgaaggatgctcttcacaagcaggccagcgtgcgcgccagcgagggtgcgatg
tcggatggccgggtgcctgcggagcaccgccagggtggcggggacttcagacgggccccc
gctcctggcaccctccaggatggtctctgccactccctcgacaggggcatctctgggaag
ggggaaggcacggagaagtcctcccaggccaaggagcttctccgatgtgaaaagttagac
agcaagctggccaacatcgattacctccgaaagaaaatgtcacttgaggacaaagaggac
aacctctgccctgtgctgaagcccaagatgacagctggctcccacgaatgcctgccaggg
aacccagtccgacccacgggtgggcagcaggagcccccgccggcttctgagagccgagct
tttgtcagcagcacccatgcagctcagatgagtgccgtctcttttgttcccctcaaggcc
ttaacaggccgggtggacagtggaacggagaagcctggcttggttgctcctgagtcccct
gttaggaagagcccctccgagtataagctggaaggtaggtctgtctcatgcctgaagccg
atcgagggcactctggacattgctctcctgtccggacctcaggcctccaagacagaactg
ccttccccagagtctgcacagagccccagcccaagtggtgacgtgagggcctctgtgcca
ccagttctccccagcagcagtgggaaaaagaacgataccaccagtgcaagagagctttct
ccttccagcttaaagatgaataaatcctacctgctggagccttggttcctgccccccagc
cgaggtctccagaattcaccagcagtttccctgcctgacccagagttcaagagggacagg
aaaggtccccatcctactgccaggagccctggaacagtcatggaaagcaatccccaacag
agagagggcagctcccctaaacaccaagaccacaccactgaccccaagcttctgacctgc
ctggggcagaacctccacagccctgacctggccaggccacgctgcccgctcccacctgaa
gcttccccctcaagggagaagccaggcctgagggaatcgtctgaaagaggccctcccaca
gccagaagcgagcgctctgctgcgagggctgacacatgcagagagccctccatggaactg
tgctttccagaaactgcgaaaaccagtgacaactccaaaaatctcctctctgtgggaagg
acccacccagatttctatacacagacccaggccatggagaaagcatgggcgccgggtggg
aaaacgaaccacaaagatggcccaggtgaggcgaggcccccgcccagagacaactcctct
ctgcactcagctggaattccctgtgagaaggagctgggcaaggtgaggcgtggcgtggaa
cccaagcccgaagcgcttcttgccaggcggtctctgcagccacctggaattgagagtgag
aagagtgaaaagctctccagtttcccatctttgcagaaagatggtgccaaggaacctgaa
aggaaggagcagcctctacaaaggcatcccagcagcatccctccgccccctctgacggcc
aaagacctgtccagcccggctgccaggcagcattgcagttccccaagccacgcttctggc
agagagccgggggccaagcccagcactgcagagcccagctcgagcccccaggaccctccc
aagcctgttgctgcgcacagtgaaagcagcagccacaagccccggcctggccctgacccg
ggccctccaaagactaagcaccccgaccggtccctctcctctcagaaaccaagtgtcggg
gccacaaagggcaaagagcctgccactcagtccctcggtggctctagcagagaggggaag
ggccacagtaagagtgggccggatgtgtttcctgctaccccaggctcccagaacaaagcc
agcgatgggattggccagggagaaggtgggccctctgtcccactgcacactgacagggct
cctctagacgccaagccacaacccaccagtggtgggcggcccctggaggtgctggagaag
cctgtgcatttgccaaggccgggacacccagggcctagtgagccagcggaccagaaactg
tccgctgttggtgaaaagcaaaccctgtctccaaagcaccccaaaccatccactgtgaaa
gattgccccaccctgtgcaaacagacagacaacagacagacagacaaaagcccgagtcag
ccggccgccaacaccgacagaagggcggaagggaagaaatgcactgaagcactttatgct
ccagcagagggcgacaagctcgaggccggcctttcctttgtgcatagcgagaaccggttg
aaaggcgcggagcggccagccgcgggggtggggaagggcttccctgaggccagagggaaa
gggcccggtccccagaagccaccgacggaggcagacaagcccaatggcatgaaacggtcc
ccctcagccactgggcagagttctttccgatccacggccctcccggaaaagtctctgagc
tgctcctccagcttccctgaaaccagggccggagttagagaggcctctgcagccagcagc
gacacctcttctgccaaggccgccgggggcatgctggagcttccagcccccagcaacagg
gaccataggaaggctcagcctgccggggagggccgaacccacatgacaaagagtgactcc
ctgccctccttccgggtctccaccctgcctctggagtcacaccaccccgacccaaacacc
atgggcggggccagccaccgggacagggctctctcggtgactgccaccgtaggggaaacc
aaagggaaggaccctgccccagcccagcctcccccagctaggaaacagaacgtgggcaga
gacgtgaccaagccatccccagccccaaacactgaccgccccatctctctttctaatgag
aaggactttgtggtacggcagaggcgggggaaagagagtttgcgtagcagccctcacaaa
aaggccttgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (76)   
   KEGG ORTHOLOGY (1)   
   RefGene (60)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (53)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (51)   
DNA sequence (89)   
   RefSeq(nuc) (51)   
   GenBank (19)   
   EMBL (19)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (235)   

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