KEGG   Homo sapiens (human): 3786
Entry
3786              CDS       T01001                                 
Symbol
KCNQ3, BFNC2, EBN2, KV7.3
Name
(RefSeq) potassium voltage-gated channel subfamily Q member 3
  KO
K04928  potassium voltage-gated channel KQT-like subfamily member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04725  Cholinergic synapse
Disease
H00806  Benign familial neonatal seizure
Drug target
Flindokalner: D04192
Retigabine: D09569
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    3786 (KCNQ3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3786 (KCNQ3)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, voltage-gated (Kv)
   3786 (KCNQ3)
SSDB
Motif
Pfam: KCNQ_channel KCNQC3-Ank-G_bd Ion_trans Ion_trans_2 Lig_chan
Other DBs
NCBI-GeneID: 3786
NCBI-ProteinID: NP_004510
OMIM: 602232
HGNC: 6297
Ensembl: ENSG00000184156
UniProt: O43525
Structure
Position
8:complement(132120861..132481095)
AA seq 872 aa
MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR
NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT
KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL
PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR
SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT
DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI
NT seq 2619 nt   +upstreamnt  +downstreamnt
atggggctcaaggcgcgcagggcggcgggggcggctggcggcggcggcgacgggggcggc
ggaggcggcggggcggctaacccagccggaggggacgcggcggcggccggcgacgaggag
cggaaagtggggctggcgcccggcgacgtggagcaagtcaccttggcgctcggggccgga
gccgacaaagacgggaccctgctgctggagggcggcggccgcgacgaggggcagcggagg
accccgcagggcatcgggctcctggccaagaccccgctgagccgcccagtcaagagaaac
aacgccaagtaccggcgcatccaaactttgatctacgacgccctggagagaccgcggggc
tgggcgctgctttaccacgcgttggtgttcctgattgtcctggggtgcttgattctggct
gtcctgaccacattcaaggagtatgagactgtctcgggagactggcttctgttactggag
acatttgctattttcatctttggagccgagtttgctttgaggatctgggctgctggatgt
tgctgccgatacaaaggctggcggggccgactgaagtttgccaggaagcccctgtgcatg
ttggacatctttgtgctgattgcctctgtgccagtggttgctgtgggaaaccaaggcaat
gttctggccacctccctgcgaagcctgcgcttcctgcagatcctgcgcatgctgcggatg
gaccggagaggtggcacctggaagcttctgggctcagccatctgtgcccacagcaaagaa
ctcatcacggcctggtacatcggtttcctgacactcatcctttcttcatttcttgtctac
ctggttgagaaagacgtcccagaggtggatgcacaaggagaggagatgaaagaggagttt
gagacctatgcagatgccctgtggtggggcctgatcacactggccaccattggctatgga
gacaagacacccaaaacgtgggaaggccgtctgattgccgccaccttttccttaattggc
gtctccttttttgcccttccagcgggcatcctggggtccgggctggccctcaaggtgcag
gagcaacaccgtcagaagcactttgagaaaaggaggaagccagctgctgagctcattcag
gctgcctggaggtattatgctaccaaccccaacaggattgacctggtggcgacatggaga
ttttatgaatcagtcgtctcttttcctttcttcaggaaagaacagctggaggcagcatcc
agccaaaagctgggtctcttggatcgggttcgcctttctaatcctcgtggtagcaatact
aaaggaaagctatttacccctctgaatgtagatgccatagaagaaagtccttctaaagaa
ccaaagcctgttggcttaaacaataaagagcgtttccgcacggccttccgcatgaaagcc
tacgctttctggcagagttctgaagatgccgggacaggtgaccccatggcggaagacagg
ggctatgggaatgacttccccatcgaagacatgatccccaccctgaaggccgccatccga
gccgtcagaattctacaattccgtctctataaaaaaaaattcaaggagactttgaggcct
tacgatgtgaaggatgtgattgagcagtattctgccgggcatctcgacatgctttccagg
ataaagtaccttcagacgagaatagatatgattttcacccctggacctccctccacgcca
aaacacaagaagtctcagaaagggtcagcattcaccttcccatcccagcaatctcccagg
aatgaaccatatgtagccagaccatccacatcagaaatcgaagaccaaagcatgatgggg
aagtttgtaaaagttgaaagacaggttcaggacatggggaagaagctggacttcctcgtg
gatatgcacatgcaacacatggaacggttgcaggtgcaggtcacggagtattacccaacc
aagggcacctcctcgccagctgaagcagagaagaaggaggacaacaggtattccgatttg
aaaaccatcatctgcaactattctgagacaggccccccggaaccaccctacagcttccac
caggtgaccattgacaaagtcagcccctatgggttttttgcacatgaccctgtgaacctg
ccccgagggggacccagttctggaaaggttcaggcaactcctccttcctcagcaacaacg
tatgtggagaggcccacggtcctgcctatcttgactcttctcgactcccgagtgagctgc
cactcccaggctgacctgcagggcccctactcggaccgaatctccccccggcagagacgt
agcatcacgcgagacagtgacacacctctgtccctgatgtcggtcaaccacgaggagctg
gagaggtctccaagtggcttcagcatctcccaggacagagatgattatgtgttcggcccc
aatggggggtcgagctggatgagggagaagcggtacctcgccgagggtgagacggacaca
gacacggaccccttcacgcccagcggctccatgcctctgtcgtccacaggggatgggatt
tctgattcagtatggaccccttccaataagcccatttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (24)   
   RefSeq(nuc) (8)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (60)   

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