KEGG   Homo sapiens (human): 3836
Entry
3836              CDS       T01001                                 
Symbol
KPNA1, IPOA5, NPI-1, RCH2, SRP1
Name
(RefSeq) karyopherin subunit alpha 1
  KO
K23940  importin subunit alpha-5
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa05132  Salmonella infection
hsa05164  Influenza A
hsa05207  Chemical carcinogenesis - receptor activation
Network
nt06181  Salmonella
nt06516  TNF signaling
  Element
N01118  Salmonella SpvD to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    3836 (KPNA1)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    3836 (KPNA1)
  09172 Infectious disease: viral
   05164 Influenza A
    3836 (KPNA1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    3836 (KPNA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    3836 (KPNA1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    3836 (KPNA1)
SSDB
Motif
Pfam: Arm IBB Arm_3 HEAT_EZ HEAT_2 HEAT V-ATPase_H_C CTNNBL
Other DBs
NCBI-GeneID: 3836
NCBI-ProteinID: NP_002255
OMIM: 600686
HGNC: 6394
Ensembl: ENSG00000114030
UniProt: P52294
Structure
Position
3:complement(122421902..122514939)
AA seq 538 aa
MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE
VMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE
VISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSS
EFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLC
RGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRR
LVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACW
TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLV
ELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDK
IEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQL
NT seq 1617 nt   +upstreamnt  +downstreamnt
atgaccaccccaggaaaagagaactttcgcctgaaaagttacaagaacaaatctctgaat
cccgatgagatgcgcaggaggagggaggaagaaggactgcagttacgaaagcagaaaaga
gaagagcagttattcaagcggagaaatgttgctacagcagaagaagaaacagaagaagaa
gttatgtcagatggaggctttcatgaggctcagattagtaacatggagatggcaccaggt
ggtgtcatcacttctgacatgattgaaatgatattttccaaaagcccagagcaacagctt
tcagcaacacagaaattcaggaagctgctttcaaaagaacctaaccctcctattgatgaa
gttatcagcacaccaggagtagtggccaggtttgtggagttcctcaaacgaaaagagaat
tgtacactgcagtttgaatcagcttgggtactgacaaatattgcttcaggaaattctctt
cagacccgaattgtgattcaggcaggagctgtgcccatcttcatagagttgctcagctca
gagtttgaagatgtccaggaacaggcagtctgggctcttggcaacattgctggagatagt
accatgtgcagggactatgtcttagactgcaatatccttccccctcttttgcagttattt
tcaaagcaaaaccgcctgaccatgacccggaatgcagtatgggctttgtctaatctctgt
agagggaaaagtccacctccagaatttgcaaaggtttctccatgtctgaatgtgctttcc
tggttgctgtttgtcagtgacactgatgtactggctgatgcctgctgggccctctcatat
ctatcagatggacccaatgataaaattcaagcggtcatcgatgcgggagtatgtaggaga
cttgtggaactgctgatgcataatgattataaagtggtttctcctgctttgcgagctgtg
ggaaacattgtcacaggggatgatattcagacacaggtaattctgaattgctcagctctg
cagagtttattgcatttgctgagtagcccaaaggaatctatcaaaaaggaagcatgttgg
acgatatctaatattacagctggaaatagggcacagatccagactgtgatagatgccaac
attttcccagccctcattagtattttacaaactgctgaatttcggacaagaaaagaagca
gcttgggccatcacaaatgcaacttctggaggatcagctgaacagatcaagtacctagta
gaactgggttgtatcaagccgctctgtgatctcctcacggtcatggactctaagattgta
caggttgccctaaatggcttggaaaatatcctgaggcttggagaacaggaagccaaaagg
aatggcactggcattaacccttactgtgctttgattgaagaagcttatggtctggataaa
attgagttcttacagagtcatgaaaaccaggagatctaccaaaaggcctttgatcttatt
gagcattacttcgggaccgaagatgaagacagcagcattgcaccccaggttgaccttaac
cagcagcagtacatcttccaacagtgtgaggctcctatggaaggtttccagctttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (48)   
   RefSeq(nuc) (6)   
   GenBank (21)   
   EMBL (21)   
3D Structure (4)   
   PDB (4)   
Protein domain (8)   
   Pfam (8)   
All databases (96)   

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