KEGG   Homo sapiens (human): 3875
Entry
3875              CDS       T01001                                 
Symbol
KRT18, CK-18, CYK18, K18
Name
(RefSeq) keratin 18
  KO
K07604  type I keratin, acidic
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
hsa05150  Staphylococcus aureus infection
Disease
H02225  Familial cirrhosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3875 (KRT18)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    3875 (KRT18)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    3875 (KRT18)
   04147 Exosome [BR:hsa04147]
    3875 (KRT18)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Types I and II: Acidic and basic keratins
     3875 (KRT18)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   3875 (KRT18)
  Exosomal proteins of other body fluids (saliva and urine)
   3875 (KRT18)
  Exosomal proteins of colorectal cancer cells
   3875 (KRT18)
  Exosomal proteins of melanoma cells
   3875 (KRT18)
SSDB
Motif
Pfam: Filament TPR_MLP1_2
Other DBs
NCBI-GeneID: 3875
NCBI-ProteinID: NP_000215
OMIM: 148070
HGNC: 6430
Ensembl: ENSG00000111057
UniProt: P05783
Position
12:52948855..52952906
AA seq 430 aa
MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS
GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG
PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN
DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP
KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR
RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA
QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS
ETNDTKVLRH
NT seq 1293 nt   +upstreamnt  +downstreamnt
atgagcttcaccactcgctccaccttctccaccaactaccggtccctgggctctgtccag
gcgcccagctacggcgcccggccggtcagcagcgcggccagcgtctatgcaggcgctggg
ggctctggttcccggatctccgtgtcccgctccaccagcttcaggggcggcatggggtcc
gggggcctggccaccgggatagccgggggtctggcaggaatgggaggcatccagaacgag
aaggagaccatgcaaagcctgaacgaccgcctggcctcttacctggacagagtgaggagc
ctggagaccgagaaccggaggctggagagcaaaatccgggagcacttggagaagaaggga
ccccaggtcagagactggagccattacttcaagatcatcgaggacctgagggctcagatc
ttcgcaaatactgtggacaatgcccgcatcgttctgcagattgacaatgcccgtcttgct
gctgatgactttagagtcaagtatgagacagagctggccatgcgccagtctgtggagaac
gacatccatgggctccgcaaggtcattgatgacaccaatatcacacgactgcagctggag
acagagatcgaggctctcaaggaggagctgctcttcatgaagaagaaccacgaagaggaa
gtaaaaggcctacaagcccagattgccagctctgggttgaccgtggaggtagatgccccc
aaatctcaggacctcgccaagatcatggcagacatccgggcccaatatgacgagctggct
cggaagaaccgagaggagctagacaagtactggtctcagcagattgaggagagcaccaca
gtggtcaccacacagtctgctgaggttggagctgctgagacgacgctcacagagctgaga
cgtacagtccagtccttggagatcgacctggactccatgagaaatctgaaggccagcttg
gagaacagcctgagggaggtggaggcccgctacgccctacagatggagcagctcaacggg
atcctgctgcaccttgagtcagagctggcacagacccgggcagagggacagcgccaggcc
caggagtatgaggccctgctgaacatcaaggtcaagctggaggctgagatcgccacctac
cgccgcctgctggaagatggcgaggactttaatcttggtgatgccttggacagcagcaac
tccatgcaaaccatccaaaagaccaccacccgccggatagtggatggcaaagtggtgtct
gagaccaatgacaccaaagttctgaggcattaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (85)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (75)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (40)   
   RefSeq(nuc) (2)   
   GenBank (19)   
   EMBL (19)   
Protein domain (2)   
   Pfam (2)   
All databases (140)   

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