KEGG   Homo sapiens (human): 389840
Entry
389840            CDS       T01001                                 
Symbol
MAP3K15, ASK3, bA723P2.3
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 15
  KO
K13986  mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    389840 (MAP3K15)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     389840 (MAP3K15)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE11 family
   389840 (MAP3K15)
SSDB
Motif
Pfam: MAP3K_TRAF_bd Pkinase HisK-N-like PK_Tyr_Ser-Thr ASK_PH TPR-S DRHyd-ASK Kinase-like SAM_KSR1 Pkinase_fungal SLIDE
Other DBs
NCBI-GeneID: 389840
NCBI-ProteinID: NP_001001671
OMIM: 300820
HGNC: 31689
Ensembl: ENSG00000180815
UniProt: Q6ZN16
Structure
Position
X:complement(19360059..19515508)
AA seq 1313 aa
MESGGGNAPAGALGAASESPQCPPPPGVEGAAGPAEPDGAAEGAAGGSGEGESGGGPRRA
LRAVYVRSESSQGGAAGGPEAGARQCLLRACEAEGAHLTSVPFGELDFGETAVLDAFYDA
DVAVVDMSDVSRQPSLFYHLGVRESFDMANNVILYHDTDADTALSLKDMVTQKNTASSGN
YYFIPYIVTPCADYFCCESDAQRRASEYMQPNWDNILGPLCMPLVDRFISLLKDIHVTSC
VYYKETLLNDIRKAREKYQGEELAKELARIKLRMDNTEVLTSDIIINLLLSYRDIQDYDA
MVKLVETLEMLPTCDLADQHNIKFHYAFALNRRNSTGDREKALQIMLQVLQSCDHPGPDM
FCLCGRIYKDIFLDSDCKDDTSRDSAIEWYRKGFELQSSLYSGINLAVLLIVAGQQFETS
LELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFSVSMLAHDVGKAVQAAERLFKLKPPVW
YLRSLVQNLLLIRRFKKTIIEHSPRQERLNFWLDIIFEATNEVTNGLRFPVLVIEPTKVY
QPSYVSINNEAEERTVSLWHVSPTEMKQMHEWNFTASSIKGISLSKFDERCCFLYVHDNS
DDFQIYFSTEEQCSRFFSLVKEMITNTAGSTVELEGETDGDTLEYEYDHDANGERVVLGK
GTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENG
YIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVL
VNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCT
IIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTA
ELLREGFLRQVNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVSPDSDAQPD
ALFERTRAPRHHLGHLLSVPDESSALEDRGLASSPEDRDQGLFLLRKDSERRAILYKILW
EEQNQVASNLQECVAQSSEELHLSVGHIKQIIGILRDFIRSPEHRVMATTISKLKVDLDF
DSSSISQIHLVLFGFQDAVNKILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELRAHFE
PTCETEGVDKDMDEAEEGYPPATGPGQEAQPHQQHLSLQLGELRQETNRLLEHLVEKERE
YQNLLRQTLEQKTQELYHLQLKLKSNCITENPAGPYGQRTDKELIDWLRLQGADAKTIEK
IVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYRRAQEASETKDKA
NT seq 3942 nt   +upstreamnt  +downstreamnt
atggagagcggcggtgggaatgctccggccggggccctcggggcggcgagcgagtcccct
cagtgcccgccgccgccgggggtggagggcgcggccgggccggcggagcccgacggggcg
gcggagggcgcggcaggcggcagcggcgagggcgagagtgggggcgggccgcggcgggct
ctgcgggcagtatacgtgcgcagtgagagctcccagggcggcgcggccggcggcccggag
gctggggcgcggcagtgcctgctgcgggcctgcgaggccgagggcgctcacctcacctcc
gtgcccttcggggagctggacttcggggagacggccgtgctcgacgccttctacgacgca
gatgttgctgtggtagacatgagcgatgtctccagacagccttccctcttctaccatctt
ggagtccgagaaagctttgacatggccaataatgtgatcttgtaccatgacaccgatgcc
gacactgctctctctttgaaggacatggtaactcaaaaaaacacagcatccagtggaaat
tattatttcatcccatacatcgtgacaccgtgcgctgattatttttgctgcgagagtgat
gcccagagacgagcctccgagtacatgcagcccaactgggacaacatcctgggcccgctg
tgcatgcctttggtggacaggttcattagcctccttaaggacatccacgtgacctcatgt
gtttattacaaagaaaccttgttaaatgacatccggaaagccagagagaaataccaaggt
gaggaactggcgaaggagctagctcggatcaagctccgcatggataatactgaggttctg
acctcagacatcatcattaacttactcctgtcctaccgtgatatccaggactatgatgcg
atggtgaagctggtggaaacactggagatgctgcctacgtgtgatttggccgatcagcat
aacattaaattccactatgcgtttgcactgaataggagaaacagcacaggtgaccgtgag
aaggctctgcagatcatgctccaggttctgcagagctgtgatcacccgggccccgacatg
ttctgcctgtgtgggaggatctacaaggacatcttcttggattcagactgcaaagatgac
accagccgcgacagcgccattgagtggtatcgcaaagggtttgaactccagtcatccctc
tattcgggaattaatcttgcagttttgctgattgttgctggacaacaatttgaaacttcc
ttggaactaaggaaaataggtgtccggctgaacagtttgttgggaagaaaagggagcttg
gagaaaatgaacaattactgggatgtgggtcagttcttcagcgtcagcatgctggcccat
gatgtcgggaaagccgtccaggcagcagagaggttgttcaaactgaaacctccagtctgg
tacctgcgatcattagttcagaacttgttactaattcggcgcttcaagaaaaccattatt
gaacactcgcccaggcaagagcggctgaacttctggttagatataatttttgaggcaaca
aatgaagtcactaatggactcagatttccagttctggtcatagagccaaccaaagtgtac
cagccttcttatgtttccataaacaatgaagccgaggagagaacagtttctttatggcat
gtctcacccacagaaatgaaacagatgcacgaatggaattttacagcctcttccataaag
ggaataagcctatcaaagtttgatgaaaggtgttgttttctttatgtccatgataattct
gatgactttcaaatctacttttccaccgaagagcagtgcagtagatttttctctttggtc
aaagagatgataaccaatacagcaggcagtacggtggagctggagggagagaccgatgga
gacaccttggagtatgagtatgaccatgatgcaaatggtgagagagttgtcttggggaaa
ggcacgtatgggattgtgtatgctggccgagatctgagcaatcaagtgcgaatagccatc
aaagaaatcccggagagagatagcaggtattctcagcctctgcacgaggagatagccctg
cacaagtaccttaagcaccgcaatatcgttcagtacctgggctctgtttcagagaacggc
tacattaagatatttatggagcaggtgcctggaggaagcctttctgctcttctgcgatcc
aaatgggggccgatgaaggaaccgacaatcaagttttacaccaaacagatcctggagggc
cttaagtatcttcatgaaaaccagatcgtgcacagagacataaagggcgataatgttctg
gtgaacacctacagcggagtggtgaaaatctccgattttggaacctcgaaacgtcttgcg
ggtgtgaacccctgcacagagacttttactggcaccctgcagtacatggcacctgagata
attgaccaagggcctcgcggatatggtgccccagccgatatctggtccctgggctgcacc
atcattgagatggccaccagcaagcctccgttccatgagcttggtgagccgcaggcagcc
atgttcaaagtgggcatgtttaagatccaccctgagattccagaagccctttcagctgaa
gcccgagccttcattttatcctgtttcgagcctgacccccacaaacgtgccaccactgct
gagctactgagagagggtttcttaaggcaggtgaacaagggcaagaagaaccgaattgcc
ttcaagccctcagaaggtccccgcggtgtcgtcctggccctgcccacacagggagagccc
atggccaccagcagcagcgagcacggctctgtctccccagactccgacgcccagcctgac
gcactctttgagaggacccgggcgcccaggcaccaccttggccacctcctcagtgttcca
gacgagagctcagccttggaagaccggggcttggcctcgtccccggaggacagggaccag
ggcctcttcctgctacgcaaggacagtgagcgccgtgccatcctgtacaaaatcctctgg
gaggagcagaaccaggtggcttccaacctgcaggagtgtgtggcccagagttccgaagag
ttgcatctctcagttggacacatcaagcaaatcattgggatcctgagggacttcatccgc
tccccagagcaccgggtgatggcgaccacaatatcaaagctcaaggtggacctggacttt
gacagctcgtccatcagtcagattcacctggtgctgttcggatttcaggatgccgtaaat
aaaattttgaggaaccacttaattaggccccactggatgttcgcgatggacaacatcatc
cgccgagcggtgcaggccgcggtcaccattctcatcccagagctccgagcccactttgag
cctacctgtgagactgaaggggtagataaggacatggatgaagcggaagagggctatccc
ccagccaccggacctggccaggaggcccagccccaccagcagcacctgagcctccagctg
ggtgagctcagacaggagaccaacagacttttggaacacctagttgaaaaagagagagag
taccagaatcttctgcggcaaactctagaacagaaaactcaagaattgtatcaccttcag
ttaaaattaaaatcgaattgtattacagagaacccagcaggcccctacgggcagagaaca
gataaagagcttatagactggttgcggctgcaaggagctgatgcaaagacaattgaaaag
attgttgaagagggttatacactttcggatattcttaatgagatcactaaggaagatcta
agataccttcgactacggggtggtctcctctgcagactctggagtgcggtctcccagtac
agaagggctcaggaggcctcagaaaccaaagacaaggcttga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (23)   
   RefSeq(nuc) (13)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (94)   

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