KEGG   Homo sapiens (human): 4058
Entry
4058              CDS       T01001                                 
Symbol
LTK, TYK1
Name
(RefSeq) leukocyte receptor tyrosine kinase
  KO
K05118  leukocyte tyrosine kinase [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    4058 (LTK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     4058 (LTK)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  ALK family
   4058 (LTK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Gly_rich cEGF FXa_inhibition
Other DBs
NCBI-GeneID: 4058
NCBI-ProteinID: NP_002335
OMIM: 151520
HGNC: 6721
Ensembl: ENSG00000062524
UniProt: P29376
Structure
Position
15:complement(41503637..41513827)
AA seq 864 aa
MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLN
SPGTEGSWLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYL
ISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCL
GESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYL
RPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGC
SEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELF
LQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHK
PPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTA
PNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQ
VAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKS
FLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVA
KIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLG
YMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYC
TQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWL
SSGLKPLKSRGLQPQNLWNPTYRS
NT seq 2595 nt   +upstreamnt  +downstreamnt
atgggctgctggggacagctgctggtgtggttcggagccgcgggcgccattctctgctct
agcccggggtcccaggagacttttctgcggtcctcgcccctgccgctggcaagtcccagc
ccccgggacccgaaagtcagcgccccgcctagtatcttggagccagcctccccgctgaat
tctccgggcaccgaggggtcttggctgttttctacctgcggggccagcggccggcatggg
cccacacagacacaatgtgacggggcgtacgcggggaccagcgtggtggtgaccgtgggg
gccgccgggcagctgagaggcgtgcagctgtggcgcgtgccgggccctggccagtatctg
atctcagcctacggagccgcgggcggcaaaggcgccaagaaccacctgtcgcgggcgcat
ggcgtcttcgtctcagcaatcttctccctcggtctcggggagtcgctgtacatcctggtg
gggcagcagggagaggacgcctgtcccggaggtagcccggagagccagctcgtctgcctc
ggggagtctcgagccgttgaagagcacgcggcgatggatgggagcgaaggggtcccgggg
tcgcggcgctgggcgggaggtggcgggggtggcgggggcgccacctacgttttccgggtg
cgcgctggcgagctggaaccgttgctggtggcggccggaggcggcggtcgggcctacctg
aggccgcgggaccgaggccggactcaggcctcccccgagaaactggagaaccgctcggag
gcgcccgggagcggcgggagaggcggggcggcaggtggtgggggcggctggacgtcgcgg
gctccctctccgcaggccggccgctcactgcaggagggggcggagggcggccagggctgc
tccgaggcttgggcgacccttggctgggccgcggccggcggcttcgggggcggcggcggg
gcctgcactgcgggcggaggcggcggcggctacagggggggcgacgcttcagagactgac
aacctctgggctgatggggaagatggagtatccttcatacaccccagcagcgagctcttc
ctgcagcctctggcagtcaccgagaaccacggagaggtagagatccgaaggcacctcaac
tgcagtcactgccctttgagagactgccaatggcaggcagagctccagctggctgaatgc
ctgtgcccagaaggcatggagctagctgtggataacgtcacctgcatggacctgcacaag
cccccaggccctctggttctgatggtggctgtggtggcaacctcaacactgagcctcctt
atggtgtgtggggtcctgattctggtgaagcagaagaagtggcagggcctgcaggagatg
aggctgccgagccctgagcttgagctgagcaagcttcgaacctctgccatcaggacagcc
cccaatccctattattgccaggtggggcttggcccggcccagtcctggcctctgccacca
ggtgtcaccgaggtttccccagccaatgttactctgctcagagccctgggccatggtgcc
tttggggaggtgtatgagggactggtaattggccttcctggggactccagtcccctgcag
gtagctatcaagaccctgccagaactctgctcgcctcaggatgagctggatttcctcatg
gaggccctcatcatcagcaagtttcgccatcagaacattgtgcggtgtgtggggctcagc
ctcagggccacccctcgcctcattctgctggaactgatgtctggaggggacatgaagagt
ttcctgaggcacagtcggccacacctgggccagccatcacctctggtcatgcgggacctg
ctgcaactggcccaggacatagcccagggctgccactacctggaggaaaatcacttcatc
cacagggatattgccgcccggaactgcctgctgagctgcgctggacccagccgagtggcc
aagattggggactttgggatggcacgagatatctaccgggccagttattaccgcaggggg
gaccgggccttgctcccagtcaagtggatgcccccagaggccttcctggagggcatcttc
acatccaagacagattcctggtcttttggggtgctgctctgggagatcttctcactgggc
tacatgccctatcctgggcgcaccaaccaggaggtgctggacttcgtcgttggaggaggc
cggatggaccctcctaggggctgcccagggcctgtgtaccgcatcatgacccagtgttgg
cagcacgagcctgagctccgccctagctttgccagcatcttggagcgtctgcagtactgc
actcaggacccggatgtgctgaattcactcctgccaatggagctggggcccaccccagag
gaggaagggacttctgggctggggaacagatctttggagtgcctaagacccccacagccc
caggaactgagtccagagaagttgaaaagctggggaggtagccctcttggcccctggctg
tcctctggcctcaagcccctcaaatccaggggcctccaacctcagaacctttggaatccc
acttatcgctcctga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (47)   
   RefSeq(nuc) (25)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (110)   

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