KEGG   Homo sapiens (human): 4072
Entry
4072              CDS       T01001                                 
Symbol
EPCAM, Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1
Name
(RefSeq) epithelial cell adhesion molecule
  KO
K06737  epithelial cell adhesion molecule
Organism
hsa  Homo sapiens (human)
Disease
H01174  Congenital diarrhea
H02565  Hereditary nonpolyposis colorectal cancer
Drug target
Catumaxomab: D09207
Edrecolomab: D03958
Tucotuzumab celmoleukin: D09027
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    4072 (EPCAM)
   04090 CD molecules [BR:hsa04090]
    4072 (EPCAM)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   4072 (EPCAM)
  Exosomal proteins of colorectal cancer cells
   4072 (EPCAM)
CD molecules [BR:hsa04090]
 Proteins
  4072 (EPCAM)
SSDB
Motif
Pfam: EPCAM-Trop-2_C EpCAM_N Thyroglobulin_1 DAG1 BCLP Glycophorin_A Trp_oprn_chp Baculo_11_kDa
Other DBs
NCBI-GeneID: 4072
NCBI-ProteinID: NP_002345
OMIM: 185535
HGNC: 11529
Ensembl: ENSG00000119888
UniProt: P16422
Structure
Position
2:47369311..47387020
AA seq 314 aa
MAPPQVLAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICS
KLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSMCWCVN
TAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKF
ITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQL
DLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAVVAGIVVLVISRKKRMAKYEKA
EIKEMGEMHRELNA
NT seq 945 nt   +upstreamnt  +downstreamnt
atggcgcccccgcaggtcctcgcgttcgggcttctgcttgccgcggcgacggcgactttt
gccgcagctcaggaagaatgtgtctgtgaaaactacaagctggccgtaaactgctttgtg
aataataatcgtcaatgccagtgtacttcagttggtgcacaaaatactgtcatttgctca
aagctggctgccaaatgtttggtgatgaaggcagaaatgaatggctcaaaacttgggaga
agagcaaaacctgaaggggccctccagaacaatgatgggctttatgatcctgactgcgat
gagagcgggctctttaaggccaagcagtgcaacggcacctccatgtgctggtgtgtgaac
actgctggggtcagaagaacagacaaggacactgaaataacctgctctgagcgagtgaga
acctactggatcatcattgaactaaaacacaaagcaagagaaaaaccttatgatagtaaa
agtttgcggactgcacttcagaaggagatcacaacgcgttatcaactggatccaaaattt
atcacgagtattttgtatgagaataatgttatcactattgatctggttcaaaattcttct
caaaaaactcagaatgatgtggacatagctgatgtggcttattattttgaaaaagatgtt
aaaggtgaatccttgtttcattctaagaaaatggacctgacagtaaatggggaacaactg
gatctggatcctggtcaaactttaatttattatgttgatgaaaaagcacctgaattctca
atgcagggtctaaaagctggtgttattgctgttattgtggttgtggtgatagcagttgtt
gctggaattgttgtgctggttatttccagaaagaagagaatggcaaagtatgagaaggct
gagataaaggagatgggtgagatgcatagggaactcaatgcataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
3D Structure (2)   
   PDB (2)   
Protein domain (8)   
   Pfam (8)   
All databases (78)   

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