KEGG   Homo sapiens (human): 4140
Entry
4140              CDS       T01001                                 
Symbol
MARK3, CTAK1, KP78, PAR1A, Par-1a, VIPB
Name
(RefSeq) microtubule affinity regulating kinase 3
  KO
K08798  MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    4140 (MARK3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4140 (MARK3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     4140 (MARK3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   4140 (MARK3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Others
     4140 (MARK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr KA1 UBA Kinase-like MELK_UBA ABC1 RIO1 UBA_2 Kdo
Other DBs
NCBI-GeneID: 4140
NCBI-ProteinID: NP_001122390
OMIM: 602678
HGNC: 6897
Ensembl: ENSG00000075413
UniProt: P27448 Q86U11
Structure
Position
14:103385415..103503831
AA seq 753 aa
MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK
TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE
VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK
AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG
VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ
IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT
YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD
HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK
ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS
THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG
STNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRF
TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL
PRLSLNGVRFKRISGTSIAFKNIASKIANELKL
NT seq 2262 nt   +upstreamnt  +downstreamnt
atgtccactaggaccccattgccaacggtgaatgaacgagacactgaaaaccacacgtca
catggagatgggcgtcaagaagttacctctcgtaccagccgctcaggagctcggtgtaga
aactctatagcctcctgtgcagatgaacaacctcacatcggaaactacagactgttgaaa
acaatcggcaaggggaattttgcaaaagtaaaattggcaagacatatccttacaggcaga
gaggttgcaataaaaataattgacaaaactcagttgaatccaacaagtctacaaaagctc
ttcagagaagtaagaataatgaagattttaaatcatcccaatatagtgaagttattcgaa
gtcattgaaactgaaaaaacactctacctaatcatggaatatgcaagtggaggtgaagta
tttgactatttggttgcacatggcaggatgaaggaaaaagaagcaagatctaaatttaga
cagattgtgtctgcagttcaatactgccatcagaaacggatcgtacatcgagacctcaag
gctgaaaatctattgttagatgccgatatgaacattaaaatagcagatttcggttttagc
aatgaatttactgttggcggtaaactcgacacgttttgtggcagtcctccatacgcagca
cctgagctcttccagggcaagaaatatgacgggccagaagtggatgtgtggagtctgggg
gtcattttatacacactagtcagtggctcacttccctttgatgggcaaaacctaaaggaa
ctgagagagagagtattaagagggaaatacagaattcccttctacatgtctacagactgt
gaaaaccttctcaaacgtttcctggtgctaaatccaattaaacgcggcactctagagcaa
atcatgaaggacaggtggatcaatgcagggcatgaagaagatgaactcaaaccatttgtt
gaaccagagctagacatctcagaccaaaaaagaatagatattatggtgggaatgggatat
tcacaagaagaaattcaagaatctcttagtaagatgaaatacgatgaaatcacagctaca
tatttgttattggggagaaaatcttcagagctggatgctagtgattccagttctagcagc
aatctttcacttgctaaggttaggccgagcagtgatctcaacaacagtactggccagtct
cctcaccacaaagtgcagagaagtgtttcttcaagccaaaagcaaagacgctacagtgac
catgctggaccagctattccttctgttgtggcgtatccgaaaaggagtcagaccagcact
gcagatagtgacctcaaagaagatggaatttcctcccggaaatcaagtggcagtgctgtt
ggaggaaagggaattgctccagccagtcccatgcttgggaatgcaagtaatcctaataag
gcggatattcctgaacgcaagaaaagctccactgtccctagtagtaacacagcatctggt
ggaatgacacgacgaaatacttatgtttgcagtgagagaactacagctgatagacactca
gtgattcagaatggcaaagaaaacagcactattcctgatcagagaactccagttgcttca
acacacagtatcagtagtgcagccaccccagatcgaatccgcttcccaagaggcactgcc
agtcgtagcactttccacggccagccccgggaacggcgaaccgcaacatataatggccct
cctgcctctcccagcctgtcccatgaagccacaccattgtcccagactcgaagccgaggc
tccactaatctctttagtaaattaacttcaaaactcacaaggagaaacatgtcattcagg
tttatcaaaaggcttccaactgaatatgagaggaacgggagatatgagggctcaagtcgc
aatgtatctgctgagcaaaaagatgaaaacaaagaagcaaagcctcgatccctacgcttc
acctggagcatgaaaaccactagttcaatggatcccggggacatgatgcgggaaatccgc
aaagtgttggacgccaataactgcgactatgagcagagggagcgcttcttgctcttctgc
gtccacggagatgggcacgcggagaacctcgtgcagtgggaaatggaagtgtgcaagctg
ccaagactgtctctgaacggggtccggtttaagcggatatcggggacatccatagccttc
aaaaatattgcttccaaaattgccaatgagctaaagctgtaa

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Ontology (4)   
   KEGG BRITE (4)   
Disease (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (73)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (70)   
DNA sequence (102)   
   RefSeq(nuc) (70)   
   GenBank (16)   
   EMBL (16)   
3D Structure (3)   
   PDB (3)   
Protein domain (10)   
   Pfam (10)   
All databases (210)   

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