KEGG   Homo sapiens (human): 4145
Entry
4145              CDS       T01001                                 
Symbol
MATK, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk
Name
(RefSeq) megakaryocyte-associated tyrosine kinase
  KO
K08888  megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04722  Neurotrophin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    4145 (MATK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    4145 (MATK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     4145 (MATK)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  CSK family
   4145 (MATK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 Kinase-like RIO1 SH3_3
Other DBs
NCBI-GeneID: 4145
NCBI-ProteinID: NP_647612
OMIM: 600038
HGNC: 6906
Ensembl: ENSG00000007264
UniProt: P42679 F1T0G6
Structure
Position
19:complement(3777973..3801799)
AA seq 507 aa
MAGRGSLVSWRAFHGCDSAEELPRVSPRFLRAWHPPPVSARMPTRRWAPGTQCITKCEHT
RPKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLM
PWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI
DEAVFFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQ
IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILHQGL
YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILV
SEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSY
GRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLAR
ELRSAGAPASVSGQDADGSTSPRSQEP
NT seq 1524 nt   +upstreamnt  +downstreamnt
atggcggggcgaggctctctggtttcctggcgggcatttcacggctgtgattctgctgag
gaacttccccgggtgagcccccgcttcctccgagcctggcacccccctcccgtctcagcc
aggatgccaacgaggcgctgggccccgggcacccagtgtatcaccaaatgcgagcacacc
cgccccaagccaggggagctggccttccgcaagggcgacgtggtcaccatcctggaggcc
tgcgagaacaagagctggtaccgcgtcaagcaccacaccagtggacaggaggggctgctg
gcagctggggcgctgcgggagcgggaggccctctccgcagaccccaagctcagcctcatg
ccgtggttccacgggaagatctcgggccaggaggctgtccagcagctgcagcctcccgag
gatgggctgttcctggtgcgggagtccgcgcgccaccccggcgactacgtcctgtgcgtg
agctttggccgcgacgtcatccactaccgcgtgctgcaccgcgacggccacctcacaatc
gatgaggccgtgttcttctgcaacctcatggacatggtggagcattacagcaaggacaag
ggcgctatctgcaccaagctggtgagaccaaagcggaaacacgggaccaagtcggccgag
gaggagctggccagggcgggctggttactgaacctgcagcatttgacattgggagcacag
atcggagagggagagtttggagctgtcctgcagggtgagtacctggggcaaaaggtggcc
gtgaagaatatcaagtgtgatgtgacagcccaggccttcctggacgagacggccgtcatg
acgaagatgcaacacgagaacctggtgcgtctcctgggcgtgatcctgcaccaggggctg
tacattgtcatggagcacgtgagcaagggcaacctggtgaactttctgcggacccggggt
cgagccctcgtgaacaccgctcagctcctgcagttttctctgcacgtggccgagggcatg
gagtacctggagagcaagaagcttgtgcaccgcgacctggccgcccgcaacatcctggtc
tcagaggacctggtggccaaggtcagcgactttggcctggccaaagccgagcggaagggg
ctagactcaagccggctgcccgtcaagtggacggcgcccgaggctctcaaacacgggaag
ttcaccagcaagtcggatgtctggagttttggggtgctgctctgggaggtcttctcatat
ggacgggctccgtaccctaaaatgtcactgaaagaggtgtcggaggccgtggagaagggg
taccgcatggaaccccccgagggctgtccaggccccgtgcacgtcctcatgagcagctgc
tgggaggcagagcccgcccgccggccacccttccgcaaactggccgagaagctggcccgg
gagctacgcagtgcaggtgccccagcctccgtctcagggcaggacgccgacggctccacc
tcgccccgaagccaggagccctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (12)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (37)   
   RefSeq(nuc) (9)   
   GenBank (14)   
   EMBL (14)   
3D Structure (3)   
   PDB (3)   
Protein domain (9)   
   Pfam (9)   
All databases (88)   

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