| Entry |
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| Symbol |
MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
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| Name |
(RefSeq) mannose binding lectin 2
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| KO |
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| Organism |
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| Pathway |
| hsa04610 | Complement and coagulation cascades |
| hsa05150 | Staphylococcus aureus infection |
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| Network |
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| Element |
| N01312 | SARS-CoV-2 S to lectin pathway of complement cascade |
| N01315 | Lectin pathway of coagulation cascade, prothrombin to thrombin |
| N01316 | SARS-CoV-2 S/N to lectin pathway of coagulation cascade |
| N01491 | Lectin pathway of complement cascade, C4/C2 to C3 convertase formation |
| N01502 | Lectin pathway of coagulation cascade, fibrinogen to fibrin |
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| Disease |
| H00105 | Mannose-binding lectin pathway component defects |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
4153 (MBL2)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
4153 (MBL2)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
4153 (MBL2)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
4153 (MBL2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
4153 (MBL2)
09183 Protein families: signaling and cellular processes
04091 Lectins [BR:hsa04091]
4153 (MBL2)
Membrane trafficking [BR:hsa04131]
Endocytosis
Phagocytosis
Opsonins
4153 (MBL2)
Lectins [BR:hsa04091]
C-Type lectins
Group 3: Collectins
4153 (MBL2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
10:complement(52765380..52772784)
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| AA seq |
248 aa
MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
LAVCEFPI |
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| NT seq |
747 nt +upstreamnt +downstreamnt
atgtccctgtttccatcactccctctccttctcctgagtatggtggcagcgtcttactca
gaaactgtgacctgtgaggatgcccaaaagacctgccctgcagtgattgcctgtagctct
ccaggcatcaacggcttcccaggcaaagatgggcgtgatggcaccaagggagaaaagggg
gaaccaggccaagggctcagaggcttacagggcccccctggaaagttggggcctccagga
aatccagggccttctgggtcaccaggaccaaagggccaaaaaggagaccctggaaaaagt
ccggatggtgatagtagcctggctgcctcagaaagaaaagctctgcaaacagaaatggca
cgtatcaaaaagtggctcaccttctctctgggcaaacaagttgggaacaagttcttcctg
accaatggtgaaataatgacctttgaaaaagtgaaggccttgtgtgtcaagttccaggcc
tctgtggccacccccaggaatgctgcagagaatggagccattcagaatctcatcaaggag
gaagccttcctgggcatcactgatgagaagacagaagggcagtttgtggatctgacagga
aatagactgacctacacaaactggaacgagggtgaacccaacaatgctggttctgatgaa
gattgtgtattgctactgaaaaatggccagtggaatgacgtcccctgctccacctcccat
ctggccgtctgtgagttccctatctga |
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