KEGG   Homo sapiens (human): 4168
Entry
4168              CDS       T01001                                 
Symbol
MCF2, ARHGEF21, DBL
Name
(RefSeq) MCF.2 cell line derived transforming sequence
  KO
K20685  guanine nucleotide exchange factor MCF2
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4168 (MCF2)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    4168 (MCF2)
SSDB
Motif
Pfam: RhoGEF CRAL_TRIO_2 PH SPG48
Other DBs
NCBI-GeneID: 4168
NCBI-ProteinID: NP_005360
OMIM: 311030
HGNC: 6940
Ensembl: ENSG00000101977
UniProt: P10911 B2R9S6
Position
X:complement(139581770..139708167)
AA seq 925 aa
MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVM
LSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELA
ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR
QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ
QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC
NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ
KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG
FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQGKKTWRQNQSNLKIEVVPDCQEKRSS
GPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRN
KKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSET
IWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKK
ALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFK
PMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWY
GEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQND
EKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYF
YPTYDENEEENRPLMRPVSEMALLY
NT seq 2778 nt   +upstreamnt  +downstreamnt
atggcagaagcaaatccccggagaggcaagatgaggttcagaaggaatgcggcttccttc
cctgggaacttgcacttggttttggttttacgtcctaccagctttcttcaacgaacgttc
acagacattggattttggtttagtcaggaggattttatgcttaaattaccagttgttatg
ctgagctcagttagtgatttgctgacatacattgatgacaagcaattaacccctgagtta
ggcggcaccttgcagtactgccacagtgaatggatcatcttcagaaatgctatagaaaat
tttgccctcacagtgaaagaaatggctcagatgttacagtcctttggaactgaactggct
gagacagaactaccagatgatattccctcaatagaagaaattctggcaattcgtgctgaa
aggtatcatctgttgaagaatgatattacagctgtaaccaaagaaggaaaaattctgcta
acaaatctggaagtgcctgacactgaaggagctgtcagttcaagactagaatgtcatcgg
caaataagtggtgactggcaaactattaataagttgctgactcaagtacatgatatggaa
acagcttttgatggattttgggaaaaacatcaattaaaaatggagcagtatctgcaacta
tggaagtttgagcaggattttcaacagcttgtgactgaagttgaatttctattaaaccaa
caagcagaactggctgatgtaacagggactatagctcaagtaaaacaaaaaataaaaaaa
ttggaaaacttagatgaaaattctcaggagctattatcaaaggcccagtttgtgatatta
catggacacaagcttgcagcaaatcaccattatgcacttgatttaatctgccagaggtgc
aatgagctacgttacctttctgatattttggttaatgagataaaagcaaaacggatacaa
ctcagcaggaccttcaaaatgcataaactcctacagcaggctcgtcaatgctgtgatgaa
ggggaatgtcttctagctaatcaggaaatagataagtttcagtctaaagaagatgctcag
aaagctctccaagacattgaaaattttcttgaaatggctctaccctttataaattatgaa
cctgaaacactgcagtatgaatttgatgtaatattatctcctgagcttaaggttcaaatg
aagactatacaactcaagcttgaaaacattcgaagtatatttgagaaccagcaggctggt
ttcaggaacctggcagataagcatgtgaggccaatccaatttgtggtacccacacctgaa
aatttggtcacatctgggacaccatttttttcatctaaacaagggaagaagacttggaga
caaaatcagagcaacttaaaaattgaagtggtgcctgattgtcaggagaagagaagttct
ggtccatcctccagtttggacaatggcaatagcttggatgttttaaagaaccacgtacta
aatgaactgatacagactgagagagtttatgttcgagaactgtatactgttttgttgggt
tatagagcggagatggataatccagagatgtttgatcttatgccacctctcctgagaaat
aaaaaggacattctctttggaaacatggcagaaatatatgaattccataacgacattttc
ttgagcagcctggaaaattgtgctcatgctccagaaagagtgggaccttgtttcctggaa
aggaaggatgattttcagatgtatgcaaaatattgtcagaataagcccagatcagaaaca
atttggaggaagtattcagaatgcgcatttttccaggaatgtcaaagaaagttaaaacac
agacttagactggattcctatttactcaaaccagtgcaacgaatcactaaatatcagtta
ttgttgaaggagctattaaaatatagcaaagactgtgaaggatctgctctgttgaagaag
gcactcgatgcaatgctggatttactgaagtcagttaatgattctatgcatcagattgca
ataaatggctatattggaaacttaaatgaactgggcaagatgataatgcaaggtggattc
agcgtttggatagggcacaagaaaggtgctacaaaaatgaaggatttggctagattcaaa
ccaatgcagcgacaccttttcttgtatgaaaaagccattgttttttgcaaaaggcgtgtt
gaaagtggagaaggctctgacagatacccgtcatacagttttaaacactgttggaaaatg
gatgaagttggaatcactgaatatgtaaaaggtgataaccgcaagtttgaaatctggtat
ggtgaaaaggaagaagtttatattgtccaggcttctaatgtagatgtgaagatgacgtgg
ctaaaagaaataagaaatattttgttgaagcagcaggaacttttgacagttaaaaaaaga
aagcaacaggatcaattaacagaacgggataagtttcagatttctcttcagcagaatgat
gaaaagcaacagggagcttttataagtactgaggaaactgaattggaacacaccagcact
gtggtggaggtctgtgaggcaattgcgtcagttcaggcagaagcaaatacagtttggact
gaggcatcacaatctgcagaaatctctgaagaacctgcggaatggtcaagcaactatttc
taccctacttatgatgaaaatgaagaagaaaataggcccctcatgagacctgtgtcggag
atggctctcctatattga

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Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (27)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (54)   
   RefSeq(nuc) (24)   
   GenBank (15)   
   EMBL (15)   
Protein domain (4)   
   Pfam (4)   
All databases (104)   

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