KEGG   Homo sapiens (human): 4298
Entry
4298              CDS       T01001                                 
Symbol
MLLT1, ENL, LTG19, YEATS1
Name
(RefSeq) MLLT1 super elongation complex subunit
  KO
K15187  YEATS domain-containing protein 1/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03250  Viral life cycle - HIV-1
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00119  MLL-AF4 fusion to transcriptional activation
N00120  MLL-ENL fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    4298 (MLLT1)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    4298 (MLLT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    4298 (MLLT1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    4298 (MLLT1)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Super elongation complex (SEC)
     4298 (MLLT1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    Dot1-containing complex
     4298 (MLLT1)
SSDB
Motif
Pfam: YEATS AHD pYEATS BET
Other DBs
NCBI-GeneID: 4298
NCBI-ProteinID: NP_005925
OMIM: 159556
HGNC: 7134
Ensembl: ENSG00000130382
UniProt: Q03111
Structure
Position
19:complement(6210381..6279975)
AA seq 559 aa
MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFP
KPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCE
KLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHG
SKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPK
EEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQ
KKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESN
SEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSS
SGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCS
KPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLF
SLDETTVRKLQSCLEAVAT
NT seq 1680 nt   +upstreamnt  +downstreamnt
atggacaatcagtgcaccgtccaggtgaggttagagctggggcatcgcgcccaactgcgc
aagaagcccaccacggaggggttcactcacgactggatggtgtttgtccgcggccccgag
caatgtgacatccagcacttcgtggagaaggtggtcttctggctgcacgacagcttcccc
aagcccagacgcgtgtgcaaggagcccccctacaaagtagaggagtcggggtacgctggc
ttcatcatgcccatcgaggtgcacttcaaaaacaaggaggagccgaggaaggtctgcttc
acctacgacctgttcctgaacctggaaggcaacccgcccgtgaaccacctgcgctgcgag
aagctcaccttcaacaaccccaccacggagttccggtacaagctcctgcgggccggcggg
gtgatggtaatgcccgaaggagcagacacggtgtccaggcccagtcccgactaccccatg
ttacccacaattccactctctgccttctctgaccccaagaagaccaaaccatcccacggc
tccaaggacgccaacaaggagagcagcaagacctccaagccacacaaggtgaccaaggag
caccgggagcggccccgcaaagactccgagagcaagagctcctccaaggagctggagcgt
gagcaggccaaaagctccaaggacacctcgcggaagctgggcgagggccggctgcccaag
gaggagaaggcgccaccgcccaaggctgccttcaaggaacccaagatggccctgaaagag
accaagctggaaagcacgtcccccaagggtgggcccccacccccacccccacccccaccc
cgggcttccagcaagcggccggccaccgccgactcgccaaagcccagcgccaagaagcag
aagaagagcagctcgaaggggtcccggagtgctccaggcacctcgccccgcacctcctcc
tcctcctccttctcggacaagaagccggccaaggacaagagcagcaccagaggggagaag
gtgaaggccgagagtgagccccgggaggccaaaaaggccctggaggtggaggagtccaac
tcagaggacgaggcctccttcaagtccgagtctgcccagtcaagcccgtccaactccagc
tccagctcagactccagctcagactcagacttcgagccatcccagaaccacagccaagga
cccctgcgctccatggtggaggacctgcagtccgaggagtccgacgaggacgactcttcg
tcaggcgaggaggctgccggcaagaccaacccggggagggactccaggttgagcttcagc
gacagcgagagtgacaacagcgccgactcctccctgcccagccgtgagcccccacccccc
cagaagccacccccgcccaacagcaaggtgtcaggccggaggagccccgagtcctgcagc
aagcctgagaagatcctcaagaagggcacctacgacaaggcctacacggatgagctggtg
gagctacaccggaggctgatggcgctgcgggagcgcaacgtgctgcagcagattgtgaat
ctgatcgaggagactggccacttcaatgtcaccaacaccaccttcgacttcgacctcttc
tccctggacgagaccaccgtgcgcaaactgcagagctgcctggaggccgtggccacatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (27)   
   RefSeq(nuc) (11)   
   GenBank (8)   
   EMBL (8)   
3D Structure (24)   
   PDB (24)   
Protein domain (4)   
   Pfam (4)   
All databases (109)   

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