KEGG   Homo sapiens (human): 4325
Entry
4325              CDS       T01001                                 
Symbol
MMP16, C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP
Name
(RefSeq) matrix metallopeptidase 16
  KO
K07996  matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04928  Parathyroid hormone synthesis, secretion and action
hsa05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    4325 (MMP16)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    4325 (MMP16)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    4325 (MMP16)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M10
   4325 (MMP16)
SSDB
Motif
Pfam: Peptidase_M10 Hemopexin DUF3377 PG_binding_1 Astacin Peptidase_M66 Peptidase_M54 Metallopep Reprolysin_3 Reprolysin_5 DUF4953
Other DBs
NCBI-GeneID: 4325
NCBI-ProteinID: NP_005932
OMIM: 602262
HGNC: 7162
Ensembl: ENSG00000156103
UniProt: P51512
Structure
Position
8:complement(88032011..88327483)
AA seq 607 aa
MILLTFSTGRRLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEVWLQKYGYLPPTDPRM
SVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRY
ALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKR
DVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDL
FLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPT
RPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNICDGNFNTLAILRREMFVF
KDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSDGNFVFFKGNKYWVFKDTTLQ
PGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVW
KGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCDGPTDRVK
EGHSPPDDVDIVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCK
RSMQEWV
NT seq 1824 nt   +upstreamnt  +downstreamnt
atgatcttactcacattcagcactggaagacggttggatttcgtgcatcattcgggggtg
tttttcttgcaaaccttgctttggattttatgtgctacagtctgcggaacggagcagtat
ttcaatgtggaggtttggttacaaaagtacggctaccttccaccgactgaccccagaatg
tcagtgctgcgctctgcagagaccatgcagtctgccctagctgccatgcagcagttctat
ggcattaacatgacaggaaaagtggacagaaacacaattgactggatgaagaagccccga
tgcggtgtacctgaccagacaagaggtagctccaaatttcatattcgtcgaaagcgatat
gcattgacaggacagaaatggcagcacaagcacatcacttacagtataaagaacgtaact
ccaaaagtaggagaccctgagactcgtaaagctattcgccgtgcctttgatgtgtggcag
aatgtaactcctctgacatttgaagaagttccctacagtgaattagaaaatggcaaacgt
gatgtggatataaccattatttttgcatctggtttccatggggacagctctccctttgat
ggagagggaggatttttggcacatgcctacttccctggaccaggaattggaggagatacc
cattttgactcagatgagccatggacactaggaaatcctaatcatgatggaaatgactta
tttcttgtagcagtccatgaactgggacatgctctgggattggagcattccaatgacccc
actgccatcatggctccattttaccagtacatggaaacagacaacttcaaactacctaat
gatgatttacagggcatccagaagatatatggtccacctgacaagattcctccacctaca
agacctctaccgacagtgcccccacaccgctctattcctccggctgacccaaggaaaaat
gacaggccaaaacctcctcggcctccaaccggcagaccctcctatcccggagccaaaccc
aacatctgtgatgggaactttaacactctagctattcttcgtcgtgagatgtttgttttc
aaggaccagtggttttggcgagtgagaaacaacagggtgatggatggatacccaatgcaa
attacttacttctggcggggcttgcctcctagtatcgatgcagtttatgaaaatagcgac
gggaattttgtgttctttaaaggtaacaaatattgggtgttcaaggatacaactcttcaa
cctggttaccctcatgacttgataacccttggaagtggaattccccctcatggtattgat
tcagccatttggtgggaggacgtcgggaaaacctatttcttcaagggagacagatattgg
agatatagtgaagaaatgaaaacaatggaccctggctatcccaagccaatcacagtctgg
aaagggatccctgaatctcctcagggagcatttgtacacaaagaaaatggctttacgtat
ttctacaaaggaaaggagtattggaaattcaacaaccagatactcaaggtagaacctgga
tatccaagatccatcctcaaggattttatgggctgtgatggaccaacagacagagttaaa
gaaggacacagcccaccagatgatgtagacattgtcatcaaactggacaacacagccagc
actgtgaaagccatagctattgtcattccctgcatcttggccttatgcctccttgtattg
gtttacactgtgttccagttcaagaggaaaggaacaccccgccacatactgtactgtaaa
cgctctatgcaagagtgggtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (31)   
   RefSeq(nuc) (5)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (65)   

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